trialr: Clinical Trial Designs in 'rstan'

A collection of clinical trial designs and methods, implemented in 'rstan' and R, including: the Continual Reassessment Method by O'Quigley et al. (1990) <doi:10.2307/2531628>; EffTox by Thall & Cook (2004) <doi:10.1111/j.0006-341X.2004.00218.x>; and the Augmented Binary method by Wason & Seaman (2013) <doi:10.1002/sim.5867>; and more. We provide functions to aid model-fitting and analysis. The 'rstan' implementations may also serve as a cookbook to anyone looking to extend or embellish these models. We hope that this package encourages the use of Bayesian methods in clinical trials. There is a preponderance of early phase trial designs because this is where Bayesian methods are used most. If there is a method you would like implemented, please get in touch.

Version:	0.1.4
Depends:	R (≥ 3.5.0), methods, Rcpp (≥ 1.0.1)
Imports:	rstan (≥ 2.18.2), rstantools (≥ 1.5.1), rlang (≥ 0.4.5), dplyr, tidyr, purrr, magrittr, stringr, ggplot2, gtools, coda, tidybayes (≥ 2.0.3), tibble (≥ 3.0.0), binom, MASS
LinkingTo:	StanHeaders (≥ 2.18.1), rstan (≥ 2.18.2), BH (≥ 1.69.0-1), Rcpp (≥ 1.0.1), RcppEigen (≥ 0.3.3.5.0)
Suggests:	testthat, knitr, rmarkdown, ggridges, covr, DiagrammeR
Published:	2020-04-06
Author:	Kristian Brock [aut, cre], Trustees of Columbia University [cph]
Maintainer:	Kristian Brock <kristian.brock at gmail.com>
BugReports:	https://github.com/brockk/trialr/issues
License:	GPL (≥ 3)
URL:	https://github.com/brockk/trialr
NeedsCompilation:	yes
SystemRequirements:	GNU make
Materials:	README NEWS
CRAN checks:	trialr results

Downloads:

Linking:

Please use the canonical form https://CRAN.R-project.org/package=trialr to link to this page.