Melds genome-wide association tests with structural equation modeling (SEM) using 'OpenMx'. This package contains low-level C/C++ code to rapidly read genetic data encoded in U.K. Biobank or 'plink' formats. Prebuilt modeling options include one and two factor models. Alternately, analyses may utilize arbitrary, user-provided SEMs. See Verhulst, Maes, & Neale (2017) <doi:10.1007/s10519-017-9842-6> for details. An updated manuscript is in preparation.
| Version: | 2.0.5 |
| Depends: | R (≥ 3.5), OpenMx (≥ 2.15.5) |
| Imports: | data.table, methods, qqman, Rcpp, lifecycle |
| LinkingTo: | BH (≥ 1.69.0-1), Rcpp |
| Suggests: | testthat (≥ 2.1.0), MASS, covr, knitr, rmarkdown, curl |
| Published: | 2020-06-14 |
| Author: | Joshua N. Pritikin [aut, cre], Bradley Verhulst [cph], Gavin Band [cph], Yann Collet [cph], Facebook, Inc. [cph], Yuta Mori [cph], Shaun Purcell [cph], Christopher Chang [cph], Wojciech Mula [cph], Kim Walisch [cph] |
| Maintainer: | Joshua N. Pritikin <jpritikin at pobox.com> |
| BugReports: | https://github.com/jpritikin/gwsem/issues |
| License: | GPL (≥ 3) |
| URL: | https://github.com/jpritikin/gwsem |
| NeedsCompilation: | yes |
| SystemRequirements: | GNU make |
| Language: | en-US |
| Materials: | README NEWS |
| CRAN checks: | gwsem results |
| Reference manual: | gwsem.pdf |
| Vignettes: |
GxE GWAS Single Factor GWAS Post GWAS Single Factor Residuals GWAS Standard GWAS Two Factor GWAS Custom GWAS growth |
| Package source: | gwsem_2.0.5.tar.gz |
| Windows binaries: | r-devel: gwsem_2.0.5.zip, r-release: gwsem_2.0.5.zip, r-oldrel: gwsem_2.0.5.zip |
| macOS binaries: | r-release: gwsem_2.0.5.tgz, r-oldrel: gwsem_2.0.5.tgz |
| Old sources: | gwsem archive |
Please use the canonical form https://CRAN.R-project.org/package=gwsem to link to this page.