Provides methods for high-throughput adaptive immune receptor repertoire sequencing (AIRR-Seq; Rep-Seq) analysis. In particular, immunoglobulin (Ig) sequence lineage reconstruction, lineage topology analysis, diversity profiling, amino acid property analysis and gene usage. Citations: Gupta and Vander Heiden, et al (2017) <doi:10.1093/bioinformatics/btv359>, Stern, Yaari and Vander Heiden, et al (2014) <doi:10.1126/scitranslmed.3008879>.
| Version: | 1.0.2 |
| Depends: | R (≥ 3.5.0), ggplot2 (≥ 3.2.0) |
| Imports: | ape, dplyr (≥ 0.8.3), graphics, grid, igraph (≥ 1.0.0), lazyeval, Matrix, methods, progress, Rcpp (≥ 0.12.12), readr, rlang, scales, seqinr, stats, stringi, tibble, tidyr (≥ 1.0.0), utils |
| LinkingTo: | Rcpp |
| Suggests: | knitr, rmarkdown, testthat |
| Published: | 2020-07-19 |
| Author: | Namita Gupta [aut], Susanna Marquez [aut], Nima Nouri [aut], Ruoyi Jiang [aut], Julian Zhou [aut], Kenneth Hoehn [aut], Daniel Gadala-Maria [ctb], Jason Vander Heiden [cre, aut], Steven Kleinstein [aut, cph] |
| Maintainer: | Jason Vander Heiden <jason.vanderheiden at gmail.com> |
| BugReports: | https://bitbucket.org/kleinstein/alakazam/issues |
| License: | AGPL-3 |
| URL: | http://alakazam.readthedocs.org |
| NeedsCompilation: | yes |
| SystemRequirements: | C++11 |
| Citation: | alakazam citation info |
| Materials: | README NEWS |
| CRAN checks: | alakazam results |
| Reference manual: | alakazam.pdf |
| Vignettes: |
Amino acid property analysis Diversity analysis Gene usage analysis Lineage reconstruction Topology analysis |
| Package source: | alakazam_1.0.2.tar.gz |
| Windows binaries: | r-devel: alakazam_1.0.2.zip, r-release: alakazam_1.0.2.zip, r-oldrel: alakazam_1.0.2.zip |
| macOS binaries: | r-release: alakazam_1.0.2.tgz, r-oldrel: alakazam_1.0.2.tgz |
| Old sources: | alakazam archive |
| Reverse imports: | rabhit, scoper, shazam, tigger, UniprotR |
Please use the canonical form https://CRAN.R-project.org/package=alakazam to link to this page.