Performs comparative bioavailability calculations for Average Bioequivalence with Expanding Limits (ABEL). Implemented are 'Method A' and 'Method B' and the detection of outliers. If the design allows, assessment of the empiric Type I Error and iteratively adjusting alpha to control the consumer risk. Average Bioequivalence - optionally with a tighter (narrow therapeutic index drugs) or wider acceptance range (Gulf Cooperation Council, South Africa: Cmax) - is implemented as well.
Version: | 1.0.15 |
Depends: | R (≥ 3.5.0) |
Imports: | readxl (≥ 1.0.0), PowerTOST (≥ 1.3.3), lmerTest, nlme, pbkrtest, graphics, grDevices |
Suggests: | knitr, rmarkdown, testthat, devtools |
Published: | 2020-07-24 |
Author: | Helmut Schütz |
Maintainer: | Helmut Schütz <helmut.schuetz at bebac.at> |
BugReports: | https://github.com/Helmut01/replicateBE/issues |
License: | GPL (≥ 3) |
URL: | https://github.com/Helmut01/replicateBE |
NeedsCompilation: | no |
Materials: | README NEWS |
CRAN checks: | replicateBE results |
Reference manual: | replicateBE.pdf |
Vignettes: |
replicateBE |
Package source: | replicateBE_1.0.15.tar.gz |
Windows binaries: | r-devel: replicateBE_1.0.15.zip, r-release: replicateBE_1.0.15.zip, r-oldrel: replicateBE_1.0.15.zip |
macOS binaries: | r-release: replicateBE_1.0.15.tgz, r-oldrel: replicateBE_1.0.15.tgz |
Old sources: | replicateBE archive |
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