Enhances various R packages that support the design and simulation of phase 1 dose-escalation trials, adding diagnostics to examine the safety characteristics of these designs in light of expected inter-individual variation in pharmacokinetics and pharmacodynamics. See Norris (2020), "Retrospective analysis of a fatal dose-finding trial" <arXiv:2004.12755>.
| Version: | 0.1-2 |
| Depends: | magrittr, escalation, data.table |
| Imports: | methods, dplyr, rlang, stringr, knitr, kableExtra |
| Suggests: | rmarkdown, bookdown, tufte, testthat |
| Published: | 2020-08-01 |
| Author: | David C. Norris |
| Maintainer: | David C. Norris <david at precisionmethods.guru> |
| License: | MIT + file LICENSE |
| URL: | https://precisionmethods.guru/ |
| NeedsCompilation: | no |
| Materials: | NEWS |
| CRAN checks: | precautionary results |
| Reference manual: | precautionary.pdf |
| Vignettes: |
Introduction to package 'precautionary' |
| Package source: | precautionary_0.1-2.tar.gz |
| Windows binaries: | r-devel: precautionary_0.1-2.zip, r-release: precautionary_0.1-2.zip, r-oldrel: precautionary_0.1-2.zip |
| macOS binaries: | r-release: precautionary_0.1-2.tgz, r-oldrel: precautionary_0.1-2.tgz |
| Old sources: | precautionary archive |
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