[aut, cre],
Brad Reisfeld [aut],
Weihsueh A. Chiu
[aut]Applying the global sensitivity analysis workflow to investigate the parameter uncertainty and sensitivity in physiologically based kinetic (PK) models, especially the physiologically based pharmacokinetic/toxicokinetic model with multivariate outputs. The package also provides some functions to check the convergence and sensitivity of model parameters (Hsieh et al., 2018 <doi:10.3389/fphar.2018.00588>).
| Version: | 1.2.0 |
| Depends: | R (≥ 3.6) |
| Imports: | ggplot2, data.table, deSolve, dplyr, getPass, magrittr, foreach, parallel, doParallel, reshape |
| Suggests: | knitr, rmarkdown, testthat |
| Published: | 2020-06-15 |
| Author: | Nan-Hung Hsieh
[aut, cre],
Brad Reisfeld [aut],
Weihsueh A. Chiu
[aut] |
| Maintainer: | Nan-Hung Hsieh <d99622005 at ntu.edu.tw> |
| BugReports: | https://github.com/nanhung/pksensi/issues |
| License: | GPL-3 | file LICENSE |
| URL: | https://github.com/nanhung/pksensi, https://nanhung.rbind.io/pksensi |
| NeedsCompilation: | no |
| Materials: | NEWS |
| CRAN checks: | pksensi results |
| Reference manual: | pksensi.pdf |
| Vignettes: |
Acetaminophen-PBPK model One-compartment PK model |
| Package source: | pksensi_1.2.0.tar.gz |
| Windows binaries: | r-devel: pksensi_1.2.0.zip, r-release: pksensi_1.2.0.zip, r-oldrel: pksensi_1.2.0.zip |
| macOS binaries: | r-release: pksensi_1.2.0.tgz, r-oldrel: pksensi_1.2.0.tgz |
| Old sources: | pksensi archive |
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