The DoseFinding package provides functions for the design and analysis
of dose-finding experiments (with focus on pharmaceutical Phase
II clinical trials). It provides functions for: multiple contrast
tests, fitting non-linear dose-response models (using Bayesian and
non-Bayesian estimation), calculating optimal designs and an
implementation of the MCPMod methodology (Pinheiro et al. (2014)
<doi:10.1002/sim.6052>).
Version: |
0.9-17 |
Depends: |
lattice, mvtnorm, R (≥ 2.15.0) |
Suggests: |
numDeriv, Rsolnp, quadprog, parallel, multcomp |
Published: |
2019-11-16 |
Author: |
Bjoern Bornkamp
[aut, cre],
Jose Pinheiro [ctb],
Frank Bretz [ctb] |
Maintainer: |
Bjoern Bornkamp <bbnkmp at gmail.com> |
License: |
GPL-3 |
NeedsCompilation: |
yes |
Materials: |
ChangeLog |
In views: |
ClinicalTrials, ExperimentalDesign |
CRAN checks: |
DoseFinding results |