The expression of X-chromosome undergoes three possible biological processes: X-chromosome inactivation (XCI), escape of the X-chromosome inactivation (XCI-E),and skewed X-chromosome inactivation (XCI-S). To analyze the X-linked genetic association for phenotype such as continuous, binary, and time-to-event outcomes with the actual process unknown, we propose a unified approach of maximizing the likelihood or partial likelihood over all of the potential biological processes. The methods are described in Wei Xu, Meiling Hao (2017) <doi:10.1002/gepi.22097>. And also see Dongxiao Han, Meiling Hao, Lianqiang Qu, Wei Xu (2019) <doi:10.1177/0962280219859037>.
| Version: | 1.0.1 |
| Depends: | R (≥ 3.1.0) |
| Imports: | survival (≥ 2.41.3) |
| Suggests: | knitr, rmarkdown, testthat |
| Published: | 2019-08-20 |
| Author: | Wei Xu [aut], Meiling Hao [aut], Yi Zhu [cre] |
| Maintainer: | Yi Zhu <yizhu87 at gmail.com> |
| BugReports: | https://github.com/qiuanzhu/xlink/issues |
| License: | GPL-2 |
| URL: | https://github.com/qiuanzhu/xlink |
| NeedsCompilation: | no |
| Materials: | NEWS |
| CRAN checks: | xlink results |
| Reference manual: | xlink.pdf |
| Vignettes: |
An Introduction to xlink |
| Package source: | xlink_1.0.1.tar.gz |
| Windows binaries: | r-devel: xlink_1.0.1.zip, r-release: xlink_1.0.1.zip, r-oldrel: xlink_1.0.1.zip |
| macOS binaries: | r-release: xlink_1.0.1.tgz, r-oldrel: xlink_1.0.1.tgz |
| Old sources: | xlink archive |
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