A Bayesian Phase I cancer vaccine trial design is implemented in this package. The design allows simultaneous evaluation of safety and immunogenicity outcomes in the context of vaccine studies. See Wang (2019) <doi:10.1002/sim.8021> for the details of the Phase I cancer vaccine trial design.
| Version: | 2.1 |
| Depends: | methods, R (≥ 3.5.0), rstan (≥ 2.19.2), Rcpp (≥ 1.0.2) |
| Imports: | sqldf (≥ 0.4), parallel (≥ 3.2) |
| LinkingTo: | BH (≥ 1.69.0-1), Rcpp (≥ 1.0.2), rstan (≥ 2.14), RcppEigen (≥ 0.3.3.5.0), StanHeaders (≥ 2.18.1-10) |
| Suggests: | knitr, shiny, rmarkdown, pander, xtable |
| Published: | 2019-08-26 |
| Author: | Zilu Wang [aut, cre] Chenguang Wang [aut, cre] Gary L Rosner [aut] Richard BS Roden [aut] Trustees of Columbia University [cph] (tools/make_cpp.R, R/stanmodels.R) |
| Maintainer: | Chenguang Wang <cwang68 at jhmi.edu> |
| License: | GPL (≥ 3) |
| NeedsCompilation: | yes |
| SystemRequirements: | GNU make |
| CRAN checks: | visit results |
| Reference manual: | visit.pdf |
| Vignettes: |
visit: Vaccine Phase I Design with Simultaneous Evaluation of Immnunogeneicity and Toxicity |
| Package source: | visit_2.1.tar.gz |
| Windows binaries: | r-devel: visit_2.1.zip, r-release: visit_2.1.zip, r-oldrel: visit_2.1.zip |
| macOS binaries: | r-release: visit_2.1.tgz, r-oldrel: visit_2.1.tgz |
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