Provides functions for the evaluation of surrogate endpoints when both the surrogate and the true endpoint are failure time variables. The approaches implemented are: (1) the two-step approach (Burzykowski et al, 2001) <doi:10.1111/1467-9876.00244> with a copula model (Clayton, Plackett, Hougaard) at the first step and either a linear regression of log-hazard ratios at the second step (either adjusted or not for measurement error); (2) mixed proportional hazard models estimated via mixed Poisson GLM (Rotolo et al, 2019 <doi:10.1177/0962280217718582>).
| Version: | 1.1.25 |
| Depends: | R (≥ 2.10), stats, optimx, grDevices |
| Imports: | copula, eha, lme4, MASS, Matrix, msm, mvmeta, optextras, parallel, parfm, survival, SurvCorr |
| Suggests: | R.rsp |
| Published: | 2019-01-18 |
| Author: | Federico Rotolo [aut], Xavier Paoletti [ctr], Marc Buyse [ctr], Tomasz Burzykowski [ctr], Stefan Michiels [ctr, cre] |
| Maintainer: | Stefan Michiels <stefan.michiels at gustaveroussy.fr> |
| License: | GPL-2 |
| NeedsCompilation: | no |
| Materials: | README NEWS |
| CRAN checks: | surrosurv results |
| Reference manual: | surrosurv.pdf |
| Vignettes: |
Validation of time-to-event surrogate endpoints using the surrosurv package Parameterization of copula functions |
| Package source: | surrosurv_1.1.25.tar.gz |
| Windows binaries: | r-devel: surrosurv_1.1.25.zip, r-release: surrosurv_1.1.25.zip, r-oldrel: surrosurv_1.1.25.zip |
| macOS binaries: | r-release: surrosurv_1.1.25.tgz, r-oldrel: surrosurv_1.1.25.tgz |
| Old sources: | surrosurv archive |
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