Package takes frequencies of mutations as reported by high throughput sequencing data from cancer and fits a theoretical neutral model of tumour evolution. Package outputs summary statistics and contains code for plotting the data and model fits. See Williams et al 2016 <doi:10.1038/ng.3489> and Williams et al 2017 <doi:10.1101/096305> for further details of the method.
Version: | 0.0.2 |
Depends: | R (≥ 3.4) |
Imports: | dplyr, ggplot2, scales, pracma, ggpmisc, cowplot |
Suggests: | knitr, rmarkdown, testthat |
Published: | 2018-05-21 |
Author: | Marc Williams [aut, cre] |
Maintainer: | Marc Williams <marcjwilliams1 at gmail.com> |
BugReports: | https://github.com/marcjwilliams1/neutralitytestr/issues |
License: | MIT + file LICENSE |
URL: | https://github.com/marcjwilliams1/neutralitytestr |
NeedsCompilation: | no |
Materials: | README NEWS |
CRAN checks: | neutralitytestr results |
Reference manual: | neutralitytestr.pdf |
Vignettes: |
neutralitytestr: Testing a neutral evolutionary model on cancer sequencing data |
Package source: | neutralitytestr_0.0.2.tar.gz |
Windows binaries: | r-devel: neutralitytestr_0.0.2.zip, r-release: neutralitytestr_0.0.2.zip, r-oldrel: neutralitytestr_0.0.2.zip |
macOS binaries: | r-release: neutralitytestr_0.0.2.tgz, r-oldrel: neutralitytestr_0.0.2.tgz |
Old sources: | neutralitytestr archive |
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