inbreedR
provides functions and workflows for the analysis of inbreeding and heterozygosity-fitness correlations (HFCs) based on molecular markers such as microsatellites and SNPs. It has four main application areas:
Quantifying variance in inbreeding through estimation of identitiy disequilibria (g2), heterozygosity-heterozygosity correlations (HHC) and variance in standardized multilocus heterozygosity (sMLH)
Calculating g2 for small and large SNP datasets. The use of data.table
and parallelization speed up bootstrapping and permutation tests
Estimating central parameters within HFC theory, such as the influence of inbreeding on heterozygosity and fitness, and their confidence intervals.
Exploring the sensitivity of these measures towards the number of genetic markers using simulations
You can install:
the latest released version from CRAN with
install.packages("inbreedR")
the latest development version from github with
if (packageVersion("devtools") < 1.6) {
install.packages("devtools")
}
devtools::install_github("mastoffel/inbreedR", build_vignettes = TRUE)
If you encounter bug or if you have any suggestions for improvement, just contact me: martin.adam.stoffel[at]gmail.com
To get started read the vignette:
vignette("inbreedR_step_by_step", package = "inbreedR")