A modular and computationally efficient R package for parameterizing, simulating, and analyzing health-economic simulation models. The package supports cohort discrete time state transition models (Briggs et al. 1998) <doi:10.2165/00019053-199813040-00003>, N-state partitioned survival models (Glasziou et al. 1990) <doi:10.1002/sim.4780091106>, and individual-level continuous time state transition models (Siebert et al. 2012) <doi:10.1016/j.jval.2012.06.014>, encompassing both Markov (time-homogeneous and time-inhomogeneous) and semi-Markov processes. Decision uncertainty from a cost-effectiveness analysis is quantified with standard graphical and tabular summaries of a probabilistic sensitivity analysis (Claxton et al. 2005, Barton et al. 2008) <doi:10.1002/hec.985>, <doi:10.1111/j.1524-4733.2008.00358.x>. Use of C++ and data.table make individual-patient simulation, probabilistic sensitivity analysis, and incorporation of patient heterogeneity fast.
| Version: | 0.3.1 |
| Depends: | R (≥ 3.5.0) |
| Imports: | data.table, flexsurv, MASS, Rcpp (≥ 0.12.16), R6, stats, survival |
| LinkingTo: | Rcpp, RcppArmadillo |
| Suggests: | covr, ggplot2, kableExtra, knitr, mstate, msm, nnet, numDeriv, pracma, rmarkdown, scales, testthat, truncnorm |
| Published: | 2020-06-02 |
| Author: | Devin Incerti [aut, cre], Jeroen P. Jansen [aut], R Core Team [ctb] (hesim uses some slightly modified C functions from base R) |
| Maintainer: | Devin Incerti <devin.incerti at gmail.com> |
| BugReports: | https://github.com/hesim-dev/hesim/issues |
| License: | GPL-3 |
| URL: | https://github.com/hesim-dev/hesim |
| NeedsCompilation: | yes |
| SystemRequirements: | C++11 |
| Materials: | README |
| CRAN checks: | hesim results |
| Reference manual: | hesim.pdf |
| Vignettes: |
Simulating costs and QALYs Getting started with a Markov Cohort Model Individualized cost-effectiveness analysis (iCEA) Introduction to hesim Time inhomogeneous Markov cohort models Markov models with multinomial logistic regression Markov and semi-Markov multi-state models Partitioned survival models |
| Package source: | hesim_0.3.1.tar.gz |
| Windows binaries: | r-devel: hesim_0.3.1.zip, r-release: hesim_0.3.1.zip, r-oldrel: hesim_0.3.1.zip |
| macOS binaries: | r-release: hesim_0.3.1.tgz, r-oldrel: hesim_0.3.1.tgz |
| Old sources: | hesim archive |
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