Programs to find the sample size or power of studies using the Sequential Parallel Comparison Design (SPCD) and programs to analyze such studies. This is a clinical trial design where patients initially on placebo who did not respond are re-randomized between placebo and active drug in a second phase and the results of the two phases are pooled. The method of analyzing binary data with this design is described in Fava,Evins, Dorer and Schoenfeld(2003) <doi:10.1159/000069738>, and the method of analyzing continuous data is described in Chen, Yang, Hung and Wang (2011) <doi:10.1016/j.cct.2011.04.006>.
Version: | 0.1.0 |
Depends: | nlme, lme4, plyr |
Published: | 2019-03-12 |
Author: | David A. Schoenfeld |
Maintainer: | David A. Schoenfeld <dschoenfeld at mgh.harvard.edu> |
License: | Unlimited |
NeedsCompilation: | no |
CRAN checks: | SPCDAnalyze results |
Reference manual: | SPCDAnalyze.pdf |
Package source: | SPCDAnalyze_0.1.0.tar.gz |
Windows binaries: | r-devel: SPCDAnalyze_0.1.0.zip, r-release: SPCDAnalyze_0.1.0.zip, r-oldrel: SPCDAnalyze_0.1.0.zip |
macOS binaries: | r-release: SPCDAnalyze_0.1.0.tgz, r-oldrel: SPCDAnalyze_0.1.0.tgz |
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