It provides a list of genes associated to diseases (g2d$clean and g2d$complete) based on the following 4 publications (GS2D, Fontaine (2016) <doi:10.18547/gcb.2016.vol2.iss1.e33>, DisGeNET, Pinero (2016) <doi:10.1093/nar/gkw943> Berto2016, Berto (2016) <doi:10.3389/fgene.2016.00031> and PsyGeNET, Sacristan (2015) <doi:10.1093/bioinformatics/btv301>). Those lists were combined and manually curated to have matching disease names. When provided a list of gene names, it calculates the disease enrichment of the gene set. The enrichment is calculated using proportion test and Fisher's exact test. Adjusted fdr p-values are returned alongside with p-values combined using the Fisher's method.
| Version: | 1.0.0 |
| Depends: | R (≥ 3.1) |
| Imports: | plyr, reshape2, magrittr, stats, metap |
| Published: | 2019-02-22 |
| Author: | Deisy Morselli Gysi and Katja Nowick |
| Maintainer: | Deisy Morselli Gysi <deisy at bioinf.uni-leipzig.de> |
| License: | GPL-2 |
| NeedsCompilation: | no |
| CRAN checks: | RichR results |
| Reference manual: | RichR.pdf |
| Package source: | RichR_1.0.0.tar.gz |
| Windows binaries: | r-devel: RichR_1.0.0.zip, r-release: RichR_1.0.0.zip, r-oldrel: RichR_1.0.0.zip |
| macOS binaries: | r-release: RichR_1.0.0.tgz, r-oldrel: RichR_1.0.0.tgz |
Please use the canonical form https://CRAN.R-project.org/package=RichR to link to this page.