This tool computes the probability of detection (POD) curve and the limit of detection (LOD), i.e. the number of copies of the target DNA sequence required to ensure a 95 % probability of detection (LOD95). Other quantiles of the LOD can be specified. This is a reimplementation of the mathematical-statistical modelling of the validation of qualitative polymerase chain reaction (PCR) methods within a single laboratory as provided by the commercial tool 'PROLab' <http://quodata.de/>. The modelling itself has been described by Uhlig et al. (2015) <doi:10.1007/s00769-015-1112-9>.
Version: | 1.2.0 |
Depends: | R (≥ 3.4.0) |
Published: | 2020-06-30 |
Author: | Markus Boenn (State Office for Consumer Protection Saxony-Anhalt, Germany) |
Maintainer: | Markus Boenn <markus.boenn.sf at gmail.com> |
License: | GPL-3 |
NeedsCompilation: | no |
Citation: | POD citation info |
Materials: | README NEWS ChangeLog |
CRAN checks: | POD results |
Reference manual: | POD.pdf |
Vignettes: |
excelmacro |
Package source: | POD_1.2.0.tar.gz |
Windows binaries: | r-devel: POD_1.2.0.zip, r-release: POD_1.2.0.zip, r-oldrel: POD_1.2.0.zip |
macOS binaries: | r-release: POD_1.2.0.tgz, r-oldrel: POD_1.2.0.tgz |
Old sources: | POD archive |
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