Maximum likelihood estimates (MLE) of the proportions of 5-mC and 5-hmC in the DNA using information from BS-conversion, TAB-conversion, and oxBS-conversion methods. One can use information from all three methods or any combination of two of them. Estimates are based on Binomial model by Qu et al. (2013) <doi:10.1093/bioinformatics/btt459> and Kiihl et al. (2019) <doi:10.1515/sagmb-2018-0031>.
Version: | 0.3.3 |
Suggests: | minfi, microbenchmark, GEOquery, knitr, rmarkdown, IlluminaHumanMethylation450kmanifest |
Published: | 2019-10-17 |
Author: | Samara Kiihl [aut, cre], Maria Jose Martinez-Garrido [aut], Arce Domingo-Relloso [aut], Jose Bermudez [aut], Maria Tellez-Plaza [aut] |
Maintainer: | Samara Kiihl <samara at ime.unicamp.br> |
BugReports: | https://github.com/samarafk/MLML2R/issues |
License: | MIT + file LICENSE |
URL: | https://github.com/samarafk/MLML2R |
NeedsCompilation: | no |
Citation: | MLML2R citation info |
CRAN checks: | MLML2R results |
Reference manual: | MLML2R.pdf |
Vignettes: |
Using MLML2R |
Package source: | MLML2R_0.3.3.tar.gz |
Windows binaries: | r-devel: MLML2R_0.3.3.zip, r-release: MLML2R_0.3.3.zip, r-oldrel: MLML2R_0.3.3.zip |
macOS binaries: | r-release: MLML2R_0.3.3.tgz, r-oldrel: MLML2R_0.3.3.tgz |
Old sources: | MLML2R archive |
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