Rank-based tests for enrichment of KOG (euKaryotic Orthologous Groups) classes with up- or down-regulated genes based on a continuous measure. The meta-analysis is based on correlation of KOG delta-ranks across datasets (delta-rank is the difference between mean rank of genes belonging to a KOG class and mean rank of all other genes). With binary measure (1 or 0 to indicate significant and non-significant genes), one-tailed Fisher's exact test for over-representation of each KOG class among significant genes will be performed.
Version: | 1.2 |
Depends: | R (≥ 2.10), pheatmap |
Published: | 2019-02-19 |
Author: | Mikhail V. Matz |
Maintainer: | Mikhail V. Matz <matz at utexas.edu> |
License: | GPL-3 |
NeedsCompilation: | no |
CRAN checks: | KOGMWU results |
Reference manual: | KOGMWU.pdf |
Package source: | KOGMWU_1.2.tar.gz |
Windows binaries: | r-devel: KOGMWU_1.2.zip, r-release: KOGMWU_1.2.zip, r-oldrel: KOGMWU_1.2.zip |
macOS binaries: | r-release: KOGMWU_1.2.tgz, r-oldrel: KOGMWU_1.2.tgz |
Old sources: | KOGMWU archive |
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