Perform differential analysis for methylation array data. Detect differentially methylated regions (DMRs) from array M-values. The core is a Non-homogeneous Hidden Markov Model for estimating spatial correlation and a novel Constrained Gaussian Mixture Model for modeling the M-value pairs of each individual locus.
Version: | 1.1.1 |
Depends: | MCMCpack, mvtnorm, ellipse |
Published: | 2017-04-21 |
Author: | Linghao SHEN |
Maintainer: | Linghao SHEN <sl013 at ie.cuhk.edu.hk> |
License: | GPL-2 | GPL-3 [expanded from: GPL] |
NeedsCompilation: | no |
CRAN checks: | DMRMark results |
Reference manual: | DMRMark.pdf |
Package source: | DMRMark_1.1.1.tar.gz |
Windows binaries: | r-devel: DMRMark_1.1.1.zip, r-release: DMRMark_1.1.1.zip, r-oldrel: DMRMark_1.1.1.zip |
macOS binaries: | r-release: DMRMark_1.1.1.tgz, r-oldrel: DMRMark_1.1.1.tgz |
Old sources: | DMRMark archive |
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