1.5.2 (2020-07-24) o fix issue with smooth monotherapy plot when dotted line was not shown due to numeric inaccuracies 1.5.1 (2020-07-02) o show smooth prediction curve on the marginal fit plot o show warning for agonist/antagonist combination when using generalized Loewe model 1.4.3 (2020-01-30) o fixes for special case of 2 flat monotherapy profiles 1.4.2 (2020-01-17) o even better support for flat monotherapies, consistent calls/colors for all representations (contour plot, summary table and 3d plot) o added clarification to description of Bliss method in the "Methodology" vignette o fixed typos 1.4.1 (2019-06-20) o improve tests 1.4.0 (2019-06-18) o added Alternative Loewe independence null model 1.3.0 (2019-02-28) o added Bliss independence null model 1.2.3 (2018-11-21) o better support for flat monotherapies 1.2.2 (2018-09-07) o make sure if no replicates are there model/unequal method is not allowed 1.2.1 (2018-08-24) o fix regression bug to allow custom axis labels for the contour plot 1.2.0 (2018-06-13) o support heterogeneous variance with new argument 'method' for 'fitSurface' 1.1.3 (2018-05-14) o show EC50 in log10 terms for monotherapy summary o allow custom compound names for plotting 1.1.2 (2018-05-07) o fix monotherapy formula in the vignette 1.1.1 (2018-01-02) o added reference to the original article o fix DESCRIPTION file according to new R CMD check policy 1.1.0 (2017-09-22) o isobologram() plot is now available for ResponseSurface objects It is also now included in the shiny app. o summary.ResponseSurface does not fail if marginal fits have constraints o Change of package maintainer 1.0.3 (2017-08-18) o Contour plot for maxR now has correct p-value labels o Summary for marginal fits does not fail if Hessian computation failed 1.0.2 (2017-07-31) o extra arguments in fitMarginals are now passed to the optimizer functions 1.0.1 (2017-06-29) o `predict` method added for the MarginalFit objects 1.0 (2017-06-28) o Initial public release