Data sets and functions for chi-squared Hardy-Weinberg and case-control association tests of highly polymorphic genetic data [e.g., human leukocyte antigen (HLA) data]. Performs association tests at multiple levels of polymorphism (haplotype, locus and HLA amino-acids) as described in Pappas DJ, Marin W, Hollenbach JA, Mack SJ (2016) <doi:10.1016/j.humimm.2015.12.006>. Combines rare variants to a common class to account for sparse cells in tables as described by Hollenbach JA, Mack SJ, Thomson G, Gourraud PA (2012) <doi:10.1007/978-1-61779-842-9_14>.
| Version: | 2.3 |
| Depends: | R (≥ 3.5.0) |
| Imports: | XML, httr, haplo.stats, parallel, knitr |
| Published: | 2019-11-12 |
| Author: | Derek Pappas, Steve Mack, Jill Hollenbach |
| Maintainer: | Steve Mack <sjmack at chori.org> |
| BugReports: | https://github.com/IgDAWG/BIGDAWG/issues |
| License: | GPL (≥ 3) |
| URL: | http://tools.immunogenomics.org/, https://github.com/IgDAWG/BIGDAWG |
| NeedsCompilation: | no |
| Materials: | NEWS |
| CRAN checks: | BIGDAWG results |
| Reference manual: | BIGDAWG.pdf |
| Vignettes: |
BIGDAWG GLSconvert |
| Package source: | BIGDAWG_2.3.tar.gz |
| Windows binaries: | r-devel: BIGDAWG_2.3.zip, r-release: BIGDAWG_2.3.zip, r-oldrel: BIGDAWG_2.3.zip |
| macOS binaries: | r-release: BIGDAWG_2.3.tgz, r-oldrel: BIGDAWG_2.3.tgz |
| Old sources: | BIGDAWG archive |
| Reverse imports: | pould, SSHAARP |
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