Last updated on 2020-08-07 01:50:03 CEST.
| Flavor | Version | Tinstall | Tcheck | Ttotal | Status | Flags |
|---|---|---|---|---|---|---|
| r-devel-linux-x86_64-debian-clang | 0.12.0 | 8.25 | 248.59 | 256.84 | OK | |
| r-devel-linux-x86_64-debian-gcc | 0.12.0 | 7.70 | 176.05 | 183.75 | OK | |
| r-devel-linux-x86_64-fedora-clang | 0.12.0 | 296.08 | OK | |||
| r-devel-linux-x86_64-fedora-gcc | 0.12.0 | 300.58 | OK | |||
| r-devel-windows-ix86+x86_64 | 0.12.0 | 30.00 | 266.00 | 296.00 | OK | |
| r-patched-linux-x86_64 | 0.12.0 | 9.95 | 231.72 | 241.67 | OK | |
| r-patched-solaris-x86 | 0.12.0 | 369.40 | OK | |||
| r-release-linux-x86_64 | 0.12.0 | 9.76 | 231.80 | 241.56 | OK | |
| r-release-macos-x86_64 | 0.12.0 | OK | ||||
| r-release-windows-ix86+x86_64 | 0.12.0 | 31.00 | 345.00 | 376.00 | OK | |
| r-oldrel-macos-x86_64 | 0.12.0 | ERROR | ||||
| r-oldrel-windows-ix86+x86_64 | 0.12.0 | 18.00 | 268.00 | 286.00 | ERROR |
Version: 0.12.0
Check: tests
Result: ERROR
Running ‘test-all.R’ [86s/86s]
Running the tests in ‘tests/test-all.R’ failed.
Last 13 lines of output:
══ testthat results ═══════════════════════════════════════════════════════════
[ OK: 542 | SKIPPED: 0 | WARNINGS: 135 | FAILED: 17 ]
1. Failure: ModuleFormatPValues: alignes output vertically (@test-modules-print.R#343)
2. Failure: ModuleConvertNormal: returns a column of numeric mean and a formatted column of character (SD) (@test-modules-print.R#447)
3. Failure: ModuleConvertNormal: returns a column of numeric mean and a formatted column of character (SD) (@test-modules-print.R#451)
4. Failure: ModuleConvertNormal: returns a column of numeric mean and a formatted column of character (SD) (@test-modules-print.R#455)
5. Failure: ModuleConvertNormal: returns a column of numeric mean and a formatted column of character (SD) (@test-modules-print.R#459)
6. Failure: ModuleConvertNormal: respects formatOptions (@test-modules-print.R#466)
7. Failure: ModuleConvertNormal: respects formatOptions (@test-modules-print.R#471)
8. Failure: ModuleConvertNormal: respects formatOptions (@test-modules-print.R#476)
9. Failure: ModuleConvertNormal: respects formatOptions (@test-modules-print.R#481)
1. ...
Error: testthat unit tests failed
Execution halted
Flavor: r-oldrel-macos-x86_64
Version: 0.12.0
Check: tests
Result: ERROR
Running 'test-all.R' [118s]
Running the tests in 'tests/test-all.R' failed.
Complete output:
> ################################################################################
> ### Unit tests for the package
> ## Reference: http://adv-r.had.co.nz/Testing.html
> ## See the testthat subdirectory for actual test code
> ## Created on: 2014-06-01
> ## Author: Kazuki Yoshida
> ################################################################################
>
>
> ### Run all tests
> ################################################################################
> library(testthat)
> test_check("tableone")
Loading required package: tableone
Overall Missing
n 418
time (mean (SD)) 1917.78 (1104.67) 0.0
status (%) 0.0
0 232 (55.5)
1 25 ( 6.0)
2 161 (38.5)
age (mean (SD)) 50.74 (10.45) 0.0
sex = f (%) 374 (89.5) 0.0
ascites = 1 (%) 24 ( 7.7) 25.4
hepato = 1 (%) 160 (51.3) 25.4
spiders = 1 (%) 90 (28.8) 25.4
edema (%) 0.0
0 354 (84.7)
0.5 44 (10.5)
1 20 ( 4.8)
bili (mean (SD)) 3.22 (4.41) 0.0
chol (mean (SD)) 369.51 (231.94) 32.1
albumin (mean (SD)) 3.50 (0.42) 0.0
copper (mean (SD)) 97.65 (85.61) 25.8
alk.phos (mean (SD)) 1982.66 (2140.39) 25.4
ast (mean (SD)) 122.56 (56.70) 25.4
trig (mean (SD)) 124.70 (65.15) 32.5
platelet (mean (SD)) 257.02 (98.33) 2.6
protime (mean (SD)) 10.73 (1.02) 0.5
stage (%) 1.4
1 21 ( 5.1)
2 92 (22.3)
3 155 (37.6)
4 144 (35.0)
Overall Missing
n 418
time (mean (SD)) 1917.78 (1104.67) 0.0
status (%) 0.0
0 232 (55.5)
1 25 ( 6.0)
2 161 (38.5)
age (mean (SD)) 50.74 (10.45) 0.0
sex = f (%) 374 (89.5) 0.0
ascites (%) 25.4
0 288 (68.9)
1 24 ( 5.7)
NA 106 (25.4)
hepato (%) 25.4
0 152 (36.4)
1 160 (38.3)
NA 106 (25.4)
spiders (%) 25.4
0 222 (53.1)
1 90 (21.5)
NA 106 (25.4)
edema (%) 0.0
0 354 (84.7)
0.5 44 (10.5)
1 20 ( 4.8)
bili (mean (SD)) 3.22 (4.41) 0.0
chol (mean (SD)) 369.51 (231.94) 32.1
albumin (mean (SD)) 3.50 (0.42) 0.0
copper (mean (SD)) 97.65 (85.61) 25.8
alk.phos (mean (SD)) 1982.66 (2140.39) 25.4
ast (mean (SD)) 122.56 (56.70) 25.4
trig (mean (SD)) 124.70 (65.15) 32.5
platelet (mean (SD)) 257.02 (98.33) 2.6
protime (mean (SD)) 10.73 (1.02) 0.5
stage (%) 1.4
1 21 ( 5.0)
2 92 (22.0)
3 155 (37.1)
4 144 (34.4)
NA 6 ( 1.4)
Stratified by trt
1 2 p test Missing
n 158 154
time (mean (SD)) 2015.62 (1094.12) 1996.86 (1155.93) 0.883 0.0
status (%) 0.894 0.0
0 83 (52.5) 85 (55.2)
1 10 ( 6.3) 9 ( 5.8)
2 65 (41.1) 60 (39.0)
age (mean (SD)) 51.42 (11.01) 48.58 (9.96) 0.018 0.0
sex = f (%) 137 (86.7) 139 (90.3) 0.421 0.0
ascites = 1 (%) 14 ( 8.9) 10 ( 6.5) 0.567 25.4
hepato = 1 (%) 73 (46.2) 87 (56.5) 0.088 25.4
spiders = 1 (%) 45 (28.5) 45 (29.2) 0.985 25.4
edema (%) 0.877 0.0
0 132 (83.5) 131 (85.1)
0.5 16 (10.1) 13 ( 8.4)
1 10 ( 6.3) 10 ( 6.5)
bili (mean (SD)) 2.87 (3.63) 3.65 (5.28) 0.131 0.0
chol (mean (SD)) 365.01 (209.54) 373.88 (252.48) 0.748 32.1
albumin (mean (SD)) 3.52 (0.44) 3.52 (0.40) 0.874 0.0
copper (mean (SD)) 97.64 (90.59) 97.65 (80.49) 0.999 25.8
alk.phos (mean (SD)) 2021.30 (2183.44) 1943.01 (2101.69) 0.747 25.4
ast (mean (SD)) 120.21 (54.52) 124.97 (58.93) 0.460 25.4
trig (mean (SD)) 124.14 (71.54) 125.25 (58.52) 0.886 32.5
platelet (mean (SD)) 258.75 (100.32) 265.20 (90.73) 0.555 2.6
protime (mean (SD)) 10.65 (0.85) 10.80 (1.14) 0.197 0.5
stage (%) 0.201 1.4
1 12 ( 7.6) 4 ( 2.6)
2 35 (22.2) 32 (20.8)
3 56 (35.4) 64 (41.6)
4 55 (34.8) 54 (35.1)
Stratified by trt:sex
1:m 2:m 1:f
n 21 15 137
time (mean (SD)) 1793.48 (1244.70) 2156.33 (1428.56) 2049.67 (1070.20)
status (%)
0 4 (19.0) 7 (46.7) 79 ( 57.7)
1 3 (14.3) 0 ( 0.0) 7 ( 5.1)
2 14 (66.7) 8 (53.3) 51 ( 37.2)
age (mean (SD)) 55.57 (12.61) 57.09 (10.07) 50.78 (10.65)
sex = f (%) 0 ( 0.0) 0 ( 0.0) 137 (100.0)
ascites = 1 (%) 1 ( 4.8) 2 (13.3) 13 ( 9.5)
hepato = 1 (%) 12 (57.1) 9 (60.0) 61 ( 44.5)
spiders = 1 (%) 3 (14.3) 1 ( 6.7) 42 ( 30.7)
edema (%)
0 17 (81.0) 12 (80.0) 115 ( 83.9)
0.5 3 (14.3) 1 ( 6.7) 13 ( 9.5)
1 1 ( 4.8) 2 (13.3) 9 ( 6.6)
bili (mean (SD)) 2.98 (2.11) 2.72 (2.46) 2.86 (3.81)
chol (mean (SD)) 403.43 (204.95) 301.00 (111.32) 358.24 (210.46)
albumin (mean (SD)) 3.63 (0.43) 3.50 (0.49) 3.50 (0.44)
copper (mean (SD)) 174.90 (105.33) 125.40 (89.18) 85.71 (82.27)
alk.phos (mean (SD)) 2486.16 (2385.32) 1734.45 (2478.07) 1950.04 (2151.35)
ast (mean (SD)) 128.71 (48.74) 112.58 (44.38) 118.91 (55.40)
trig (mean (SD)) 145.81 (56.62) 114.86 (39.59) 120.28 (73.41)
platelet (mean (SD)) 232.65 (97.38) 240.13 (73.93) 262.59 (100.53)
protime (mean (SD)) 10.84 (0.94) 11.23 (0.97) 10.62 (0.84)
stage (%)
1 2 ( 9.5) 1 ( 6.7) 10 ( 7.3)
2 4 (19.0) 2 (13.3) 31 ( 22.6)
3 7 (33.3) 5 (33.3) 49 ( 35.8)
4 8 (38.1) 7 (46.7) 47 ( 34.3)
Stratified by trt:sex
2:f p test Missing
n 139
time (mean (SD)) 1979.65 (1127.52) 0.730 0.0
status (%) 0.033 0.0
0 78 ( 56.1)
1 9 ( 6.5)
2 52 ( 37.4)
age (mean (SD)) 47.66 (9.54) <0.001 0.0
sex = f (%) 139 (100.0) <0.001 0.0
ascites = 1 (%) 8 ( 5.8) 0.516 25.4
hepato = 1 (%) 78 ( 56.1) 0.208 25.4
spiders = 1 (%) 44 ( 31.7) 0.089 25.4
edema (%) 0.906 0.0
0 119 ( 85.6)
0.5 12 ( 8.6)
1 8 ( 5.8)
bili (mean (SD)) 3.75 (5.50) 0.394 0.0
chol (mean (SD)) 381.73 (262.26) 0.512 32.1
albumin (mean (SD)) 3.53 (0.39) 0.585 0.0
copper (mean (SD)) 94.64 (79.25) <0.001 25.8
alk.phos (mean (SD)) 1965.52 (2066.15) 0.706 25.4
ast (mean (SD)) 126.30 (60.27) 0.598 25.4
trig (mean (SD)) 126.38 (60.22) 0.370 32.5
platelet (mean (SD)) 267.95 (92.20) 0.362 2.6
protime (mean (SD)) 10.75 (1.15) 0.137 0.5
stage (%) 0.646 1.4
1 3 ( 2.2)
2 30 ( 21.6)
3 59 ( 42.4)
4 47 ( 33.8)
Stratified by trt
Overall 1 2
n 418 158 154
time (mean (SD)) 1917.78 (1104.67) 2015.62 (1094.12) 1996.86 (1155.93)
status (%)
0 232 (55.5) 83 (52.5) 85 (55.2)
1 25 ( 6.0) 10 ( 6.3) 9 ( 5.8)
2 161 (38.5) 65 (41.1) 60 (39.0)
age (mean (SD)) 50.74 (10.45) 51.42 (11.01) 48.58 (9.96)
sex = f (%) 374 (89.5) 137 (86.7) 139 (90.3)
ascites = 1 (%) 24 ( 7.7) 14 ( 8.9) 10 ( 6.5)
hepato = 1 (%) 160 (51.3) 73 (46.2) 87 (56.5)
spiders = 1 (%) 90 (28.8) 45 (28.5) 45 (29.2)
edema (%)
0 354 (84.7) 132 (83.5) 131 (85.1)
0.5 44 (10.5) 16 (10.1) 13 ( 8.4)
1 20 ( 4.8) 10 ( 6.3) 10 ( 6.5)
bili (mean (SD)) 3.22 (4.41) 2.87 (3.63) 3.65 (5.28)
chol (mean (SD)) 369.51 (231.94) 365.01 (209.54) 373.88 (252.48)
albumin (mean (SD)) 3.50 (0.42) 3.52 (0.44) 3.52 (0.40)
copper (mean (SD)) 97.65 (85.61) 97.64 (90.59) 97.65 (80.49)
alk.phos (mean (SD)) 1982.66 (2140.39) 2021.30 (2183.44) 1943.01 (2101.69)
ast (mean (SD)) 122.56 (56.70) 120.21 (54.52) 124.97 (58.93)
trig (mean (SD)) 124.70 (65.15) 124.14 (71.54) 125.25 (58.52)
platelet (mean (SD)) 257.02 (98.33) 258.75 (100.32) 265.20 (90.73)
protime (mean (SD)) 10.73 (1.02) 10.65 (0.85) 10.80 (1.14)
stage (%)
1 21 ( 5.1) 12 ( 7.6) 4 ( 2.6)
2 92 (22.3) 35 (22.2) 32 (20.8)
3 155 (37.6) 56 (35.4) 64 (41.6)
4 144 (35.0) 55 (34.8) 54 (35.1)
Stratified by trt
p test Missing
n
time (mean (SD)) 0.883 0.0
status (%) 0.894 0.0
0
1
2
age (mean (SD)) 0.018 0.0
sex = f (%) 0.421 0.0
ascites = 1 (%) 0.567 25.4
hepato = 1 (%) 0.088 25.4
spiders = 1 (%) 0.985 25.4
edema (%) 0.877 0.0
0
0.5
1
bili (mean (SD)) 0.131 0.0
chol (mean (SD)) 0.748 32.1
albumin (mean (SD)) 0.874 0.0
copper (mean (SD)) 0.999 25.8
alk.phos (mean (SD)) 0.747 25.4
ast (mean (SD)) 0.460 25.4
trig (mean (SD)) 0.886 32.5
platelet (mean (SD)) 0.555 2.6
protime (mean (SD)) 0.197 0.5
stage (%) 0.201 1.4
1
2
3
4
Stratified by trt:sex
Overall 1:m 2:m
n 418 21 15
time (mean (SD)) 1917.78 (1104.67) 1793.48 (1244.70) 2156.33 (1428.56)
status (%)
0 232 (55.5) 4 (19.0) 7 (46.7)
1 25 ( 6.0) 3 (14.3) 0 ( 0.0)
2 161 (38.5) 14 (66.7) 8 (53.3)
age (mean (SD)) 50.74 (10.45) 55.57 (12.61) 57.09 (10.07)
sex = f (%) 374 (89.5) 0 ( 0.0) 0 ( 0.0)
ascites = 1 (%) 24 ( 7.7) 1 ( 4.8) 2 (13.3)
hepato = 1 (%) 160 (51.3) 12 (57.1) 9 (60.0)
spiders = 1 (%) 90 (28.8) 3 (14.3) 1 ( 6.7)
edema (%)
0 354 (84.7) 17 (81.0) 12 (80.0)
0.5 44 (10.5) 3 (14.3) 1 ( 6.7)
1 20 ( 4.8) 1 ( 4.8) 2 (13.3)
bili (mean (SD)) 3.22 (4.41) 2.98 (2.11) 2.72 (2.46)
chol (mean (SD)) 369.51 (231.94) 403.43 (204.95) 301.00 (111.32)
albumin (mean (SD)) 3.50 (0.42) 3.63 (0.43) 3.50 (0.49)
copper (mean (SD)) 97.65 (85.61) 174.90 (105.33) 125.40 (89.18)
alk.phos (mean (SD)) 1982.66 (2140.39) 2486.16 (2385.32) 1734.45 (2478.07)
ast (mean (SD)) 122.56 (56.70) 128.71 (48.74) 112.58 (44.38)
trig (mean (SD)) 124.70 (65.15) 145.81 (56.62) 114.86 (39.59)
platelet (mean (SD)) 257.02 (98.33) 232.65 (97.38) 240.13 (73.93)
protime (mean (SD)) 10.73 (1.02) 10.84 (0.94) 11.23 (0.97)
stage (%)
1 21 ( 5.1) 2 ( 9.5) 1 ( 6.7)
2 92 (22.3) 4 (19.0) 2 (13.3)
3 155 (37.6) 7 (33.3) 5 (33.3)
4 144 (35.0) 8 (38.1) 7 (46.7)
Stratified by trt:sex
1:f 2:f p test Missing
n 137 139
time (mean (SD)) 2049.67 (1070.20) 1979.65 (1127.52) 0.730 0.0
status (%) 0.033 0.0
0 79 ( 57.7) 78 ( 56.1)
1 7 ( 5.1) 9 ( 6.5)
2 51 ( 37.2) 52 ( 37.4)
age (mean (SD)) 50.78 (10.65) 47.66 (9.54) <0.001 0.0
sex = f (%) 137 (100.0) 139 (100.0) <0.001 0.0
ascites = 1 (%) 13 ( 9.5) 8 ( 5.8) 0.516 25.4
hepato = 1 (%) 61 ( 44.5) 78 ( 56.1) 0.208 25.4
spiders = 1 (%) 42 ( 30.7) 44 ( 31.7) 0.089 25.4
edema (%) 0.906 0.0
0 115 ( 83.9) 119 ( 85.6)
0.5 13 ( 9.5) 12 ( 8.6)
1 9 ( 6.6) 8 ( 5.8)
bili (mean (SD)) 2.86 (3.81) 3.75 (5.50) 0.394 0.0
chol (mean (SD)) 358.24 (210.46) 381.73 (262.26) 0.512 32.1
albumin (mean (SD)) 3.50 (0.44) 3.53 (0.39) 0.585 0.0
copper (mean (SD)) 85.71 (82.27) 94.64 (79.25) <0.001 25.8
alk.phos (mean (SD)) 1950.04 (2151.35) 1965.52 (2066.15) 0.706 25.4
ast (mean (SD)) 118.91 (55.40) 126.30 (60.27) 0.598 25.4
trig (mean (SD)) 120.28 (73.41) 126.38 (60.22) 0.370 32.5
platelet (mean (SD)) 262.59 (100.53) 267.95 (92.20) 0.362 2.6
protime (mean (SD)) 10.62 (0.84) 10.75 (1.15) 0.137 0.5
stage (%) 0.646 1.4
1 10 ( 7.3) 3 ( 2.2)
2 31 ( 22.6) 30 ( 21.6)
3 49 ( 35.8) 59 ( 42.4)
4 47 ( 34.3) 47 ( 33.8)
Stratified by trt
1 2
n 158 154
time (mean (SD)) 2015.62 (1094.12) 1996.86 (1155.93)
status (%)
0 83 (52.5) 85 ( 55.2)
1 10 ( 6.3) 9 ( 5.8)
2 65 (41.1) 60 ( 39.0)
trt = 2 (%) 0 ( 0.0) 154 (100.0)
age (mean (SD)) 51.42 (11.01) 48.58 (9.96)
sex = f (%) 137 (86.7) 139 ( 90.3)
ascites = 1 (%) 14 ( 8.9) 10 ( 6.5)
hepato = 1 (%) 73 (46.2) 87 ( 56.5)
spiders = 1 (%) 45 (28.5) 45 ( 29.2)
edema (%)
0 132 (83.5) 131 ( 85.1)
0.5 16 (10.1) 13 ( 8.4)
1 10 ( 6.3) 10 ( 6.5)
bili (median [IQR]) 1.40 [0.80, 3.20] 1.30 [0.72, 3.60]
chol (median [IQR]) 315.50 [247.75, 417.00] 303.50 [254.25, 377.00]
albumin (mean (SD)) 3.52 (0.44) 3.52 (0.40)
copper (median [IQR]) 73.00 [40.00, 121.00] 73.00 [43.00, 139.00]
alk.phos (median [IQR]) 1214.50 [840.75, 2028.00] 1283.00 [922.50, 1949.75]
ast (mean (SD)) 120.21 (54.52) 124.97 (58.93)
trig (median [IQR]) 106.00 [84.50, 146.00] 113.00 [84.50, 155.00]
platelet (mean (SD)) 258.75 (100.32) 265.20 (90.73)
protime (mean (SD)) 10.65 (0.85) 10.80 (1.14)
stage (%)
1 12 ( 7.6) 4 ( 2.6)
2 35 (22.2) 32 ( 20.8)
3 56 (35.4) 64 ( 41.6)
4 55 (34.8) 54 ( 35.1)
Stratified by trt
SMD Missing
n
time (mean (SD)) 0.017 0.0
status (%) 0.054 0.0
0
1
2
trt = 2 (%) NaN 25.4
age (mean (SD)) 0.270 0.0
sex = f (%) 0.111 0.0
ascites = 1 (%) 0.089 25.4
hepato = 1 (%) 0.207 25.4
spiders = 1 (%) 0.016 25.4
edema (%) 0.058 0.0
0
0.5
1
bili (median [IQR]) 0.171 0.0
chol (median [IQR]) 0.038 32.1
albumin (mean (SD)) 0.018 0.0
copper (median [IQR]) <0.001 25.8
alk.phos (median [IQR]) 0.037 25.4
ast (mean (SD)) 0.084 25.4
trig (median [IQR]) 0.017 32.5
platelet (mean (SD)) 0.067 2.6
protime (mean (SD)) 0.146 0.5
stage (%) 0.246 1.4
1
2
3
4
Stratified by trt
1 2
n 158 154
time (mean (SD)) 2015.62 (1094.12) 1996.86 (1155.93)
status (%)
0 83 (52.5) 85 ( 55.2)
1 10 ( 6.3) 9 ( 5.8)
2 65 (41.1) 60 ( 39.0)
trt = 2 (%) 0 ( 0.0) 154 (100.0)
age (mean (SD)) 51.42 (11.01) 48.58 (9.96)
sex = f (%) 137 (86.7) 139 ( 90.3)
ascites = 1 (%) 14 ( 8.9) 10 ( 6.5)
hepato = 1 (%) 73 (46.2) 87 ( 56.5)
spiders = 1 (%) 45 (28.5) 45 ( 29.2)
edema (%)
0 132 (83.5) 131 ( 85.1)
0.5 16 (10.1) 13 ( 8.4)
1 10 ( 6.3) 10 ( 6.5)
bili (median [IQR]) 1.40 [0.80, 3.20] 1.30 [0.72, 3.60]
chol (median [IQR]) 315.50 [247.75, 417.00] 303.50 [254.25, 377.00]
albumin (mean (SD)) 3.52 (0.44) 3.52 (0.40)
copper (median [IQR]) 73.00 [40.00, 121.00] 73.00 [43.00, 139.00]
alk.phos (median [IQR]) 1214.50 [840.75, 2028.00] 1283.00 [922.50, 1949.75]
ast (mean (SD)) 120.21 (54.52) 124.97 (58.93)
trig (median [IQR]) 106.00 [84.50, 146.00] 113.00 [84.50, 155.00]
platelet (mean (SD)) 258.75 (100.32) 265.20 (90.73)
protime (mean (SD)) 10.65 (0.85) 10.80 (1.14)
stage (%)
1 12 ( 7.6) 4 ( 2.6)
2 35 (22.2) 32 ( 20.8)
3 56 (35.4) 64 ( 41.6)
4 55 (34.8) 54 ( 35.1)
Stratified by trt
SMD Missing
n
time (mean (SD)) 0.017 0.0
status (%) 0.054 0.0
0
1
2
trt = 2 (%) NaN 25.4
age (mean (SD)) 0.270 0.0
sex = f (%) 0.111 0.0
ascites = 1 (%) 0.089 25.4
hepato = 1 (%) 0.207 25.4
spiders = 1 (%) 0.016 25.4
edema (%) 0.058 0.0
0
0.5
1
bili (median [IQR]) 0.171 0.0
chol (median [IQR]) 0.038 32.1
albumin (mean (SD)) 0.018 0.0
copper (median [IQR]) <0.001 25.8
alk.phos (median [IQR]) 0.037 25.4
ast (mean (SD)) 0.084 25.4
trig (median [IQR]) 0.017 32.5
platelet (mean (SD)) 0.067 2.6
protime (mean (SD)) 0.146 0.5
stage (%) 0.246 1.4
1
2
3
4
Overall
n 418
time (mean (SD)) 1917.78 (1104.67)
status (%)
0 232 (55.5)
1 25 ( 6.0)
2 161 (38.5)
age (mean (SD)) 50.74 (10.45)
sex = f (%) 374 (89.5)
ascites = 1 (%) 24 ( 7.7)
hepato = 1 (%) 160 (51.3)
spiders = 1 (%) 90 (28.8)
edema (%)
0 354 (84.7)
0.5 44 (10.5)
1 20 ( 4.8)
bili (mean (SD)) 3.22 (4.41)
chol (mean (SD)) 369.51 (231.94)
albumin (mean (SD)) 3.50 (0.42)
copper (mean (SD)) 97.65 (85.61)
alk.phos (mean (SD)) 1982.66 (2140.39)
ast (mean (SD)) 122.56 (56.70)
trig (mean (SD)) 124.70 (65.15)
platelet (mean (SD)) 257.02 (98.33)
protime (mean (SD)) 10.73 (1.02)
stage (%)
1 21 ( 5.1)
2 92 (22.3)
3 155 (37.6)
4 144 (35.0)
Overall
n 418
time (mean (SD)) 1917.78 (1104.67)
status (%)
0 232 (55.5)
1 25 ( 6.0)
2 161 (38.5)
age (mean (SD)) 50.74 (10.45)
sex (%) 374 (89.5)
ascites (%) 24 ( 7.7)
hepato (%) 160 (51.3)
spiders (%) 90 (28.8)
edema (%)
0 354 (84.7)
0.5 44 (10.5)
1 20 ( 4.8)
bili (mean (SD)) 3.22 (4.41)
chol (mean (SD)) 369.51 (231.94)
albumin (mean (SD)) 3.50 (0.42)
copper (mean (SD)) 97.65 (85.61)
alk.phos (mean (SD)) 1982.66 (2140.39)
ast (mean (SD)) 122.56 (56.70)
trig (mean (SD)) 124.70 (65.15)
platelet (mean (SD)) 257.02 (98.33)
protime (mean (SD)) 10.73 (1.02)
stage (%)
1 21 ( 5.1)
2 92 (22.3)
3 155 (37.6)
4 144 (35.0)
Overall
n 418
time (mean (SD)) 1917.78 (1104.67)
status (%)
0 232 (55.5)
1 25 ( 6.0)
2 161 (38.5)
age (mean (SD)) 50.74 (10.45)
sex = f (%) 374 (89.5)
ascites = 1 (%) 24 ( 7.7)
hepato = 1 (%) 160 (51.3)
spiders = 1 (%) 90 (28.8)
edema (%)
0 354 (84.7)
0.5 44 (10.5)
1 20 ( 4.8)
bili (mean (SD)) 3.22 (4.41)
chol (mean (SD)) 369.51 (231.94)
albumin (mean (SD)) 3.50 (0.42)
copper (mean (SD)) 97.65 (85.61)
alk.phos (mean (SD)) 1982.66 (2140.39)
ast (mean (SD)) 122.56 (56.70)
trig (mean (SD)) 124.70 (65.15)
platelet (mean (SD)) 257.02 (98.33)
protime (mean (SD)) 10.73 (1.02)
stage (%)
1 21 ( 5.1)
2 92 (22.3)
3 155 (37.6)
4 144 (35.0)
Overall
n 418
time (mean (SD)) 1917.78 (1104.67)
status (%)
0 232 (55.5)
1 25 ( 6.0)
2 161 (38.5)
Age in Years (mean (SD)) 50.74 (10.45)
Female Sex = f (%) 374 (89.5)
ascites = 1 (%) 24 ( 7.7)
hepato = 1 (%) 160 (51.3)
spiders = 1 (%) 90 (28.8)
edema (%)
0 354 (84.7)
0.5 44 (10.5)
1 20 ( 4.8)
bili (mean (SD)) 3.22 (4.41)
chol (mean (SD)) 369.51 (231.94)
albumin (mean (SD)) 3.50 (0.42)
copper (mean (SD)) 97.65 (85.61)
alk.phos (mean (SD)) 1982.66 (2140.39)
ast (mean (SD)) 122.56 (56.70)
trig (mean (SD)) 124.70 (65.15)
platelet (mean (SD)) 257.02 (98.33)
protime (mean (SD)) 10.73 (1.02)
Stage of the Disease (%)
1 21 ( 5.1)
2 92 (22.3)
3 155 (37.6)
4 144 (35.0)
Stratified by trt
1 2 p test
n 158 154
time (mean (SD)) 2015.62 (1094.12) 1996.86 (1155.93) 0.883
status (%) 0.894
0 83 (52.5) 85 (55.2)
1 10 ( 6.3) 9 ( 5.8)
2 65 (41.1) 60 (39.0)
age (mean (SD)) 51.42 (11.01) 48.58 (9.96) 0.018
sex = f (%) 137 (86.7) 139 (90.3) 0.421
ascites = 1 (%) 14 ( 8.9) 10 ( 6.5) 0.567
hepato = 1 (%) 73 (46.2) 87 (56.5) 0.088
spiders = 1 (%) 45 (28.5) 45 (29.2) 0.985
edema (%) 0.877
0 132 (83.5) 131 (85.1)
0.5 16 (10.1) 13 ( 8.4)
1 10 ( 6.3) 10 ( 6.5)
bili (mean (SD)) 2.87 (3.63) 3.65 (5.28) 0.131
chol (mean (SD)) 365.01 (209.54) 373.88 (252.48) 0.748
albumin (mean (SD)) 3.52 (0.44) 3.52 (0.40) 0.874
copper (mean (SD)) 97.64 (90.59) 97.65 (80.49) 0.999
alk.phos (mean (SD)) 2021.30 (2183.44) 1943.01 (2101.69) 0.747
ast (mean (SD)) 120.21 (54.52) 124.97 (58.93) 0.460
trig (mean (SD)) 124.14 (71.54) 125.25 (58.52) 0.886
platelet (mean (SD)) 258.75 (100.32) 265.20 (90.73) 0.555
protime (mean (SD)) 10.65 (0.85) 10.80 (1.14) 0.197
stage (%) 0.201
1 12 ( 7.6) 4 ( 2.6)
2 35 (22.2) 32 (20.8)
3 56 (35.4) 64 (41.6)
4 55 (34.8) 54 (35.1)
Stratified by trt
1 2 p test
n 158 154
time (mean (SD)) 2015.62 (1094.12) 1996.86 (1155.93) 0.883
status (%) 0.894
0 83 (52.5) 85 (55.2)
1 10 ( 6.3) 9 ( 5.8)
2 65 (41.1) 60 (39.0)
age (mean (SD)) 51.42 (11.01) 48.58 (9.96) 0.018
sex = f (%) 137 (86.7) 139 (90.3) 0.421
ascites = 1 (%) 14 ( 8.9) 10 ( 6.5) 0.567
hepato = 1 (%) 73 (46.2) 87 (56.5) 0.088
spiders = 1 (%) 45 (28.5) 45 (29.2) 0.985
edema (%) 0.877
0 132 (83.5) 131 (85.1)
0.5 16 (10.1) 13 ( 8.4)
1 10 ( 6.3) 10 ( 6.5)
bili (mean (SD)) 2.87 (3.63) 3.65 (5.28) 0.131
chol (mean (SD)) 365.01 (209.54) 373.88 (252.48) 0.748
albumin (mean (SD)) 3.52 (0.44) 3.52 (0.40) 0.874
copper (mean (SD)) 97.64 (90.59) 97.65 (80.49) 0.999
alk.phos (mean (SD)) 2021.30 (2183.44) 1943.01 (2101.69) 0.747
ast (mean (SD)) 120.21 (54.52) 124.97 (58.93) 0.460
trig (mean (SD)) 124.14 (71.54) 125.25 (58.52) 0.886
platelet (mean (SD)) 258.75 (100.32) 265.20 (90.73) 0.555
protime (mean (SD)) 10.65 (0.85) 10.80 (1.14) 0.197
stage (%) 0.201
1 12 ( 7.6) 4 ( 2.6)
2 35 (22.2) 32 (20.8)
3 56 (35.4) 64 (41.6)
4 55 (34.8) 54 (35.1)
Overall
n 418
time (mean (SD)) 1917.78 (1104.67)
status (%)
0 232 (55.5)
1 25 ( 6.0)
2 161 (38.5)
age (mean (SD)) 50.74 (10.45)
sex = f (%) 374 (89.5)
ascites = 1 (%) 24 ( 7.7)
hepato = 1 (%) 160 (51.3)
spiders = 1 (%) 90 (28.8)
edema (%)
0 354 (84.7)
0.5 44 (10.5)
1 20 ( 4.8)
bili (mean (SD)) 3.22 (4.41)
chol (mean (SD)) 369.51 (231.94)
albumin (mean (SD)) 3.50 (0.42)
copper (mean (SD)) 97.65 (85.61)
alk.phos (mean (SD)) 1982.66 (2140.39)
ast (mean (SD)) 122.56 (56.70)
trig (mean (SD)) 124.70 (65.15)
platelet (mean (SD)) 257.02 (98.33)
protime (mean (SD)) 10.73 (1.02)
stage (%)
1 21 ( 5.1)
2 92 (22.3)
3 155 (37.6)
4 144 (35.0)
Overall
n 418
time (mean (SD)) 1917.78 (1104.67)
status (%)
0 232 (55.5)
1 25 ( 6.0)
2 161 (38.5)
age (mean (SD)) 50.74 (10.45)
sex = f (%) 374 (89.5)
ascites = 1 (%) 24 ( 7.7)
hepato = 1 (%) 160 (51.3)
spiders = 1 (%) 90 (28.8)
edema (%)
0 354 (84.7)
0.5 44 (10.5)
1 20 ( 4.8)
bili (mean (SD)) 3.22 (4.41)
chol (mean (SD)) 369.51 (231.94)
albumin (mean (SD)) 3.50 (0.42)
copper (mean (SD)) 97.65 (85.61)
alk.phos (mean (SD)) 1982.66 (2140.39)
ast (mean (SD)) 122.56 (56.70)
trig (mean (SD)) 124.70 (65.15)
platelet (mean (SD)) 257.02 (98.33)
protime (mean (SD)) 10.73 (1.02)
stage (%)
1 21 ( 5.1)
2 92 (22.3)
3 155 (37.6)
4 144 (35.0)
Overall
n 418
time (mean (SD)) 1917.78 (1104.67)
status (%)
0 232 (55.5)
1 25 ( 6.0)
2 161 (38.5)
age (mean (SD)) 50.74 (10.45)
sex = f (%) 374 (89.5)
ascites (%)
0 288 (68.9)
1 24 ( 5.7)
NA 106 (25.4)
hepato (%)
0 152 (36.4)
1 160 (38.3)
NA 106 (25.4)
spiders (%)
0 222 (53.1)
1 90 (21.5)
NA 106 (25.4)
edema (%)
0 354 (84.7)
0.5 44 (10.5)
1 20 ( 4.8)
bili (mean (SD)) 3.22 (4.41)
chol (mean (SD)) 369.51 (231.94)
albumin (mean (SD)) 3.50 (0.42)
copper (mean (SD)) 97.65 (85.61)
alk.phos (mean (SD)) 1982.66 (2140.39)
ast (mean (SD)) 122.56 (56.70)
trig (mean (SD)) 124.70 (65.15)
platelet (mean (SD)) 257.02 (98.33)
protime (mean (SD)) 10.73 (1.02)
stage (%)
1 21 ( 5.0)
2 92 (22.0)
3 155 (37.1)
4 144 (34.4)
NA 6 ( 1.4)
Overall
n 418
time (mean (SD)) 1917.78 (1104.67)
status (%)
0 232 (55.5)
1 25 ( 6.0)
2 161 (38.5)
age (mean (SD)) 50.74 (10.45)
sex = f (%) 374 (89.5)
ascites (%)
0 288 (68.9)
1 24 ( 5.7)
NA 106 (25.4)
hepato (%)
0 152 (36.4)
1 160 (38.3)
NA 106 (25.4)
spiders (%)
0 222 (53.1)
1 90 (21.5)
NA 106 (25.4)
edema (%)
0 354 (84.7)
0.5 44 (10.5)
1 20 ( 4.8)
bili (mean (SD)) 3.22 (4.41)
chol (mean (SD)) 369.51 (231.94)
albumin (mean (SD)) 3.50 (0.42)
copper (mean (SD)) 97.65 (85.61)
alk.phos (mean (SD)) 1982.66 (2140.39)
ast (mean (SD)) 122.56 (56.70)
trig (mean (SD)) 124.70 (65.15)
platelet (mean (SD)) 257.02 (98.33)
protime (mean (SD)) 10.73 (1.02)
stage (%)
1 21 ( 5.0)
2 92 (22.0)
3 155 (37.1)
4 144 (34.4)
NA 6 ( 1.4)
Stratified by trt:sex
1:m 2:m 1:f
n 21 15 137
time (mean (SD)) 1793.48 (1244.70) 2156.33 (1428.56) 2049.67 (1070.20)
status (%)
0 4 (19.0) 7 (46.7) 79 ( 57.7)
1 3 (14.3) 0 ( 0.0) 7 ( 5.1)
2 14 (66.7) 8 (53.3) 51 ( 37.2)
age (mean (SD)) 55.57 (12.61) 57.09 (10.07) 50.78 (10.65)
sex = f (%) 0 ( 0.0) 0 ( 0.0) 137 (100.0)
ascites = 1 (%) 1 ( 4.8) 2 (13.3) 13 ( 9.5)
hepato = 1 (%) 12 (57.1) 9 (60.0) 61 ( 44.5)
spiders = 1 (%) 3 (14.3) 1 ( 6.7) 42 ( 30.7)
edema (%)
0 17 (81.0) 12 (80.0) 115 ( 83.9)
0.5 3 (14.3) 1 ( 6.7) 13 ( 9.5)
1 1 ( 4.8) 2 (13.3) 9 ( 6.6)
bili (mean (SD)) 2.98 (2.11) 2.72 (2.46) 2.86 (3.81)
chol (mean (SD)) 403.43 (204.95) 301.00 (111.32) 358.24 (210.46)
albumin (mean (SD)) 3.63 (0.43) 3.50 (0.49) 3.50 (0.44)
copper (mean (SD)) 174.90 (105.33) 125.40 (89.18) 85.71 (82.27)
alk.phos (mean (SD)) 2486.16 (2385.32) 1734.45 (2478.07) 1950.04 (2151.35)
ast (mean (SD)) 128.71 (48.74) 112.58 (44.38) 118.91 (55.40)
trig (mean (SD)) 145.81 (56.62) 114.86 (39.59) 120.28 (73.41)
platelet (mean (SD)) 232.65 (97.38) 240.13 (73.93) 262.59 (100.53)
protime (mean (SD)) 10.84 (0.94) 11.23 (0.97) 10.62 (0.84)
stage (%)
1 2 ( 9.5) 1 ( 6.7) 10 ( 7.3)
2 4 (19.0) 2 (13.3) 31 ( 22.6)
3 7 (33.3) 5 (33.3) 49 ( 35.8)
4 8 (38.1) 7 (46.7) 47 ( 34.3)
Stratified by trt:sex
2:f p test
n 139
time (mean (SD)) 1979.65 (1127.52) 0.730
status (%) 0.033
0 78 ( 56.1)
1 9 ( 6.5)
2 52 ( 37.4)
age (mean (SD)) 47.66 (9.54) <0.001
sex = f (%) 139 (100.0) <0.001
ascites = 1 (%) 8 ( 5.8) 0.516
hepato = 1 (%) 78 ( 56.1) 0.208
spiders = 1 (%) 44 ( 31.7) 0.089
edema (%) 0.906
0 119 ( 85.6)
0.5 12 ( 8.6)
1 8 ( 5.8)
bili (mean (SD)) 3.75 (5.50) 0.394
chol (mean (SD)) 381.73 (262.26) 0.512
albumin (mean (SD)) 3.53 (0.39) 0.585
copper (mean (SD)) 94.64 (79.25) <0.001
alk.phos (mean (SD)) 1965.52 (2066.15) 0.706
ast (mean (SD)) 126.30 (60.27) 0.598
trig (mean (SD)) 126.38 (60.22) 0.370
platelet (mean (SD)) 267.95 (92.20) 0.362
protime (mean (SD)) 10.75 (1.15) 0.137
stage (%) 0.646
1 3 ( 2.2)
2 30 ( 21.6)
3 59 ( 42.4)
4 47 ( 33.8)
Stratified by trt:sex
1:m 2:m 1:f
n 21 15 137
time (mean (SD)) 1793.48 (1244.70) 2156.33 (1428.56) 2049.67 (1070.20)
status (%)
0 4 (19.0) 7 (46.7) 79 ( 57.7)
1 3 (14.3) 0 ( 0.0) 7 ( 5.1)
2 14 (66.7) 8 (53.3) 51 ( 37.2)
age (mean (SD)) 55.57 (12.61) 57.09 (10.07) 50.78 (10.65)
sex = f (%) 0 ( 0.0) 0 ( 0.0) 137 (100.0)
ascites = 1 (%) 1 ( 4.8) 2 (13.3) 13 ( 9.5)
hepato = 1 (%) 12 (57.1) 9 (60.0) 61 ( 44.5)
spiders = 1 (%) 3 (14.3) 1 ( 6.7) 42 ( 30.7)
edema (%)
0 17 (81.0) 12 (80.0) 115 ( 83.9)
0.5 3 (14.3) 1 ( 6.7) 13 ( 9.5)
1 1 ( 4.8) 2 (13.3) 9 ( 6.6)
bili (mean (SD)) 2.98 (2.11) 2.72 (2.46) 2.86 (3.81)
chol (mean (SD)) 403.43 (204.95) 301.00 (111.32) 358.24 (210.46)
albumin (mean (SD)) 3.63 (0.43) 3.50 (0.49) 3.50 (0.44)
copper (mean (SD)) 174.90 (105.33) 125.40 (89.18) 85.71 (82.27)
alk.phos (mean (SD)) 2486.16 (2385.32) 1734.45 (2478.07) 1950.04 (2151.35)
ast (mean (SD)) 128.71 (48.74) 112.58 (44.38) 118.91 (55.40)
trig (mean (SD)) 145.81 (56.62) 114.86 (39.59) 120.28 (73.41)
platelet (mean (SD)) 232.65 (97.38) 240.13 (73.93) 262.59 (100.53)
protime (mean (SD)) 10.84 (0.94) 11.23 (0.97) 10.62 (0.84)
stage (%)
1 2 ( 9.5) 1 ( 6.7) 10 ( 7.3)
2 4 (19.0) 2 (13.3) 31 ( 22.6)
3 7 (33.3) 5 (33.3) 49 ( 35.8)
4 8 (38.1) 7 (46.7) 47 ( 34.3)
Stratified by trt:sex
2:f p test
n 139
time (mean (SD)) 1979.65 (1127.52) 0.730
status (%) 0.033
0 78 ( 56.1)
1 9 ( 6.5)
2 52 ( 37.4)
age (mean (SD)) 47.66 (9.54) <0.001
sex = f (%) 139 (100.0) <0.001
ascites = 1 (%) 8 ( 5.8) 0.516
hepato = 1 (%) 78 ( 56.1) 0.208
spiders = 1 (%) 44 ( 31.7) 0.089
edema (%) 0.906
0 119 ( 85.6)
0.5 12 ( 8.6)
1 8 ( 5.8)
bili (mean (SD)) 3.75 (5.50) 0.394
chol (mean (SD)) 381.73 (262.26) 0.512
albumin (mean (SD)) 3.53 (0.39) 0.585
copper (mean (SD)) 94.64 (79.25) <0.001
alk.phos (mean (SD)) 1965.52 (2066.15) 0.706
ast (mean (SD)) 126.30 (60.27) 0.598
trig (mean (SD)) 126.38 (60.22) 0.370
platelet (mean (SD)) 267.95 (92.20) 0.362
protime (mean (SD)) 10.75 (1.15) 0.137
stage (%) 0.646
1 3 ( 2.2)
2 30 ( 21.6)
3 59 ( 42.4)
4 47 ( 33.8)
Stratified by trt
1 2 p
n 158 154
time (mean (SD)) 2015.6203 (1094.1233) 1996.8636 (1155.9289) 0.88305
status (%) 0.89351
0 83 (52.532) 85 (55.195)
1 10 ( 6.329) 9 ( 5.844)
2 65 (41.139) 60 (38.961)
age (mean (SD)) 51.4191 (11.0072) 48.5825 (9.9578) 0.01767
sex = f (%) 137 (86.709) 139 (90.260) 0.42123
ascites = 1 (%) 14 ( 8.861) 10 ( 6.494) 0.56729
hepato = 1 (%) 73 (46.203) 87 (56.494) 0.08821
spiders = 1 (%) 45 (28.481) 45 (29.221) 0.98466
edema (%) 0.87682
0 132 (83.544) 131 (85.065)
0.5 16 (10.127) 13 ( 8.442)
1 10 ( 6.329) 10 ( 6.494)
bili (mean (SD)) 2.8734 (3.6289) 3.6487 (5.2819) 0.13094
chol (mean (SD)) 365.0143 (209.5439) 373.8819 (252.4846) 0.74799
albumin (mean (SD)) 3.5163 (0.4433) 3.5238 (0.3958) 0.87388
copper (mean (SD)) 97.6433 (90.5901) 97.6536 (80.4865) 0.99916
alk.phos (mean (SD)) 2021.2975 (2183.4358) 1943.0104 (2101.6873) 0.74726
ast (mean (SD)) 120.2087 (54.5214) 124.9650 (58.9313) 0.45970
trig (mean (SD)) 124.1367 (71.5391) 125.2517 (58.5211) 0.88604
platelet (mean (SD)) 258.7500 (100.3247) 265.2039 (90.7294) 0.55451
protime (mean (SD)) 10.6532 (0.8514) 10.8000 (1.1382) 0.19714
stage (%) 0.20130
1 12 ( 7.595) 4 ( 2.597)
2 35 (22.152) 32 (20.779)
3 56 (35.443) 64 (41.558)
4 55 (34.810) 54 (35.065)
Stratified by trt
test
n
time (mean (SD))
status (%)
0
1
2
age (mean (SD))
sex = f (%)
ascites = 1 (%)
hepato = 1 (%)
spiders = 1 (%)
edema (%)
0
0.5
1
bili (mean (SD))
chol (mean (SD))
albumin (mean (SD))
copper (mean (SD))
alk.phos (mean (SD))
ast (mean (SD))
trig (mean (SD))
platelet (mean (SD))
protime (mean (SD))
stage (%)
1
2
3
4
Stratified by trt
1 2 p
n 158 154
time (mean (SD)) 2015.6203 (1094.1233) 1996.8636 (1155.9289) 0.88305
status (%) 0.89351
0 83 (52.532) 85 (55.195)
1 10 ( 6.329) 9 ( 5.844)
2 65 (41.139) 60 (38.961)
age (mean (SD)) 51.4191 (11.0072) 48.5825 (9.9578) 0.01767
sex = f (%) 137 (86.709) 139 (90.260) 0.42123
ascites = 1 (%) 14 ( 8.861) 10 ( 6.494) 0.56729
hepato = 1 (%) 73 (46.203) 87 (56.494) 0.08821
spiders = 1 (%) 45 (28.481) 45 (29.221) 0.98466
edema (%) 0.87682
0 132 (83.544) 131 (85.065)
0.5 16 (10.127) 13 ( 8.442)
1 10 ( 6.329) 10 ( 6.494)
bili (mean (SD)) 2.8734 (3.6289) 3.6487 (5.2819) 0.13094
chol (mean (SD)) 365.0143 (209.5439) 373.8819 (252.4846) 0.74799
albumin (mean (SD)) 3.5163 (0.4433) 3.5238 (0.3958) 0.87388
copper (mean (SD)) 97.6433 (90.5901) 97.6536 (80.4865) 0.99916
alk.phos (mean (SD)) 2021.2975 (2183.4358) 1943.0104 (2101.6873) 0.74726
ast (mean (SD)) 120.2087 (54.5214) 124.9650 (58.9313) 0.45970
trig (mean (SD)) 124.1367 (71.5391) 125.2517 (58.5211) 0.88604
platelet (mean (SD)) 258.7500 (100.3247) 265.2039 (90.7294) 0.55451
protime (mean (SD)) 10.6532 (0.8514) 10.8000 (1.1382) 0.19714
stage (%) 0.20130
1 12 ( 7.595) 4 ( 2.597)
2 35 (22.152) 32 (20.779)
3 56 (35.443) 64 (41.558)
4 55 (34.810) 54 (35.065)
Stratified by trt
test
n
time (mean (SD))
status (%)
0
1
2
age (mean (SD))
sex = f (%)
ascites = 1 (%)
hepato = 1 (%)
spiders = 1 (%)
edema (%)
0
0.5
1
bili (mean (SD))
chol (mean (SD))
albumin (mean (SD))
copper (mean (SD))
alk.phos (mean (SD))
ast (mean (SD))
trig (mean (SD))
platelet (mean (SD))
protime (mean (SD))
stage (%)
1
2
3
4
Stratified by trt
1 2
n 158 154
time (mean (SD)) 2015.62 (1094.12) 1996.86 (1155.93)
status (%)
0 83 (52.5) 85 (55.2)
1 10 ( 6.3) 9 ( 5.8)
2 65 (41.1) 60 (39.0)
age (mean (SD)) 51.42 (11.01) 48.58 (9.96)
sex = f (%) 137 (86.7) 139 (90.3)
ascites = 1 (%) 14 ( 8.9) 10 ( 6.5)
hepato = 1 (%) 73 (46.2) 87 (56.5)
spiders = 1 (%) 45 (28.5) 45 (29.2)
edema (%)
0 132 (83.5) 131 (85.1)
0.5 16 (10.1) 13 ( 8.4)
1 10 ( 6.3) 10 ( 6.5)
bili (mean (SD)) 2.87 (3.63) 3.65 (5.28)
chol (mean (SD)) 365.01 (209.54) 373.88 (252.48)
albumin (mean (SD)) 3.52 (0.44) 3.52 (0.40)
copper (mean (SD)) 97.64 (90.59) 97.65 (80.49)
alk.phos (mean (SD)) 2021.30 (2183.44) 1943.01 (2101.69)
ast (mean (SD)) 120.21 (54.52) 124.97 (58.93)
trig (mean (SD)) 124.14 (71.54) 125.25 (58.52)
platelet (mean (SD)) 258.75 (100.32) 265.20 (90.73)
protime (mean (SD)) 10.65 (0.85) 10.80 (1.14)
stage (%)
1 12 ( 7.6) 4 ( 2.6)
2 35 (22.2) 32 (20.8)
3 56 (35.4) 64 (41.6)
4 55 (34.8) 54 (35.1)
Stratified by trt
1 2
n 158 154
time (mean (SD)) 2015.62 (1094.12) 1996.86 (1155.93)
status (%)
0 83 (52.5) 85 (55.2)
1 10 ( 6.3) 9 ( 5.8)
2 65 (41.1) 60 (39.0)
age (mean (SD)) 51.42 (11.01) 48.58 (9.96)
sex = f (%) 137 (86.7) 139 (90.3)
ascites = 1 (%) 14 ( 8.9) 10 ( 6.5)
hepato = 1 (%) 73 (46.2) 87 (56.5)
spiders = 1 (%) 45 (28.5) 45 (29.2)
edema (%)
0 132 (83.5) 131 (85.1)
0.5 16 (10.1) 13 ( 8.4)
1 10 ( 6.3) 10 ( 6.5)
bili (mean (SD)) 2.87 (3.63) 3.65 (5.28)
chol (mean (SD)) 365.01 (209.54) 373.88 (252.48)
albumin (mean (SD)) 3.52 (0.44) 3.52 (0.40)
copper (mean (SD)) 97.64 (90.59) 97.65 (80.49)
alk.phos (mean (SD)) 2021.30 (2183.44) 1943.01 (2101.69)
ast (mean (SD)) 120.21 (54.52) 124.97 (58.93)
trig (mean (SD)) 124.14 (71.54) 125.25 (58.52)
platelet (mean (SD)) 258.75 (100.32) 265.20 (90.73)
protime (mean (SD)) 10.65 (0.85) 10.80 (1.14)
stage (%)
1 12 ( 7.6) 4 ( 2.6)
2 35 (22.2) 32 (20.8)
3 56 (35.4) 64 (41.6)
4 55 (34.8) 54 (35.1)
Stratified by trt
1 2
n 158 154
time (mean (SD)) 2015.62 (1094.12) 1996.86 (1155.93)
status (%)
0 83 (52.5) 85 (55.2)
1 10 ( 6.3) 9 ( 5.8)
2 65 (41.1) 60 (39.0)
age (mean (SD)) 51.42 (11.01) 48.58 (9.96)
sex = f (%) 137 (86.7) 139 (90.3)
ascites = 1 (%) 14 ( 8.9) 10 ( 6.5)
hepato = 1 (%) 73 (46.2) 87 (56.5)
spiders = 1 (%) 45 (28.5) 45 (29.2)
edema (%)
0 132 (83.5) 131 (85.1)
0.5 16 (10.1) 13 ( 8.4)
1 10 ( 6.3) 10 ( 6.5)
bili (median [IQR]) 1.40 [0.80, 3.20] 1.30 [0.72, 3.60]
chol (median [IQR]) 315.50 [247.75, 417.00] 303.50 [254.25, 377.00]
albumin (mean (SD)) 3.52 (0.44) 3.52 (0.40)
copper (median [IQR]) 73.00 [40.00, 121.00] 73.00 [43.00, 139.00]
alk.phos (median [IQR]) 1214.50 [840.75, 2028.00] 1283.00 [922.50, 1949.75]
ast (mean (SD)) 120.21 (54.52) 124.97 (58.93)
trig (median [IQR]) 106.00 [84.50, 146.00] 113.00 [84.50, 155.00]
platelet (mean (SD)) 258.75 (100.32) 265.20 (90.73)
protime (mean (SD)) 10.65 (0.85) 10.80 (1.14)
stage (%)
1 12 ( 7.6) 4 ( 2.6)
2 35 (22.2) 32 (20.8)
3 56 (35.4) 64 (41.6)
4 55 (34.8) 54 (35.1)
Stratified by trt
p test
n
time (mean (SD)) 0.883
status (%) 0.884 exact
0
1
2
age (mean (SD)) 0.018
sex = f (%) 0.421
ascites = 1 (%) 0.567
hepato = 1 (%) 0.088
spiders = 1 (%) 0.985
edema (%) 0.877
0
0.5
1
bili (median [IQR]) 0.842 nonnorm
chol (median [IQR]) 0.544 nonnorm
albumin (mean (SD)) 0.874
copper (median [IQR]) 0.717 nonnorm
alk.phos (median [IQR]) 0.812 nonnorm
ast (mean (SD)) 0.460
trig (median [IQR]) 0.370 nonnorm
platelet (mean (SD)) 0.555
protime (mean (SD)) 0.197
stage (%) 0.205 exact
1
2
3
4
Stratified by trt
1 2
n 158 154
time (mean (SD)) 2015.62 (1094.12) 1996.86 (1155.93)
status (%)
0 83 (52.5) 85 (55.2)
1 10 ( 6.3) 9 ( 5.8)
2 65 (41.1) 60 (39.0)
age (mean (SD)) 51.42 (11.01) 48.58 (9.96)
sex = f (%) 137 (86.7) 139 (90.3)
ascites = 1 (%) 14 ( 8.9) 10 ( 6.5)
hepato = 1 (%) 73 (46.2) 87 (56.5)
spiders = 1 (%) 45 (28.5) 45 (29.2)
edema (%)
0 132 (83.5) 131 (85.1)
0.5 16 (10.1) 13 ( 8.4)
1 10 ( 6.3) 10 ( 6.5)
bili (median [IQR]) 1.40 [0.80, 3.20] 1.30 [0.72, 3.60]
chol (median [IQR]) 315.50 [247.75, 417.00] 303.50 [254.25, 377.00]
albumin (mean (SD)) 3.52 (0.44) 3.52 (0.40)
copper (median [IQR]) 73.00 [40.00, 121.00] 73.00 [43.00, 139.00]
alk.phos (median [IQR]) 1214.50 [840.75, 2028.00] 1283.00 [922.50, 1949.75]
ast (mean (SD)) 120.21 (54.52) 124.97 (58.93)
trig (median [IQR]) 106.00 [84.50, 146.00] 113.00 [84.50, 155.00]
platelet (mean (SD)) 258.75 (100.32) 265.20 (90.73)
protime (mean (SD)) 10.65 (0.85) 10.80 (1.14)
stage (%)
1 12 ( 7.6) 4 ( 2.6)
2 35 (22.2) 32 (20.8)
3 56 (35.4) 64 (41.6)
4 55 (34.8) 54 (35.1)
Stratified by trt
p test
n
time (mean (SD)) 0.883
status (%) 0.884 exact
0
1
2
age (mean (SD)) 0.018
sex = f (%) 0.421
ascites = 1 (%) 0.567
hepato = 1 (%) 0.088
spiders = 1 (%) 0.985
edema (%) 0.877
0
0.5
1
bili (median [IQR]) 0.842 nonnorm
chol (median [IQR]) 0.544 nonnorm
albumin (mean (SD)) 0.874
copper (median [IQR]) 0.717 nonnorm
alk.phos (median [IQR]) 0.812 nonnorm
ast (mean (SD)) 0.460
trig (median [IQR]) 0.370 nonnorm
platelet (mean (SD)) 0.555
protime (mean (SD)) 0.197
stage (%) 0.205 exact
1
2
3
4
Stratified by trt
1
n 158
time (mean (SD)) 2015.62 (1094.12)
status (%)
0 83 (52.5)
1 10 ( 6.3)
2 65 (41.1)
age (mean (SD)) 51.42 (11.01)
sex = f (%) 137 (86.7)
ascites = 1 (%) 14 ( 8.9)
hepato = 1 (%) 73 (46.2)
spiders = 1 (%) 45 (28.5)
edema (%)
0 132 (83.5)
0.5 16 (10.1)
1 10 ( 6.3)
bili (median [range]) 1.40 [0.30, 20.00]
chol (median [range]) 315.50 [127.00, 1712.00]
albumin (mean (SD)) 3.52 (0.44)
copper (median [range]) 73.00 [9.00, 588.00]
alk.phos (median [range]) 1214.50 [369.00, 11552.00]
ast (mean (SD)) 120.21 (54.52)
trig (median [range]) 106.00 [33.00, 598.00]
platelet (mean (SD)) 258.75 (100.32)
protime (mean (SD)) 10.65 (0.85)
stage (%)
1 12 ( 7.6)
2 35 (22.2)
3 56 (35.4)
4 55 (34.8)
Stratified by trt
2 p test
n 154
time (mean (SD)) 1996.86 (1155.93) 0.883
status (%) 0.894
0 85 (55.2)
1 9 ( 5.8)
2 60 (39.0)
age (mean (SD)) 48.58 (9.96) 0.018
sex = f (%) 139 (90.3) 0.421
ascites = 1 (%) 10 ( 6.5) 0.567
hepato = 1 (%) 87 (56.5) 0.088
spiders = 1 (%) 45 (29.2) 0.985
edema (%) 0.877
0 131 (85.1)
0.5 13 ( 8.4)
1 10 ( 6.5)
bili (median [range]) 1.30 [0.30, 28.00] 0.842 nonnorm
chol (median [range]) 303.50 [120.00, 1775.00] 0.544 nonnorm
albumin (mean (SD)) 3.52 (0.40) 0.874
copper (median [range]) 73.00 [4.00, 558.00] 0.717 nonnorm
alk.phos (median [range]) 1283.00 [289.00, 13862.40] 0.812 nonnorm
ast (mean (SD)) 124.97 (58.93) 0.460
trig (median [range]) 113.00 [44.00, 432.00] 0.370 nonnorm
platelet (mean (SD)) 265.20 (90.73) 0.555
protime (mean (SD)) 10.80 (1.14) 0.197
stage (%) 0.201
1 4 ( 2.6)
2 32 (20.8)
3 64 (41.6)
4 54 (35.1)
Stratified by trt
1
n 158
time (mean (SD)) 2015.62 (1094.12)
status (%)
0 83 (52.5)
1 10 ( 6.3)
2 65 (41.1)
age (mean (SD)) 51.42 (11.01)
sex = f (%) 137 (86.7)
ascites = 1 (%) 14 ( 8.9)
hepato = 1 (%) 73 (46.2)
spiders = 1 (%) 45 (28.5)
edema (%)
0 132 (83.5)
0.5 16 (10.1)
1 10 ( 6.3)
bili (median [range]) 1.40 [0.30, 20.00]
chol (median [range]) 315.50 [127.00, 1712.00]
albumin (mean (SD)) 3.52 (0.44)
copper (median [range]) 73.00 [9.00, 588.00]
alk.phos (median [range]) 1214.50 [369.00, 11552.00]
ast (mean (SD)) 120.21 (54.52)
trig (median [range]) 106.00 [33.00, 598.00]
platelet (mean (SD)) 258.75 (100.32)
protime (mean (SD)) 10.65 (0.85)
stage (%)
1 12 ( 7.6)
2 35 (22.2)
3 56 (35.4)
4 55 (34.8)
Stratified by trt
2 p test
n 154
time (mean (SD)) 1996.86 (1155.93) 0.883
status (%) 0.894
0 85 (55.2)
1 9 ( 5.8)
2 60 (39.0)
age (mean (SD)) 48.58 (9.96) 0.018
sex = f (%) 139 (90.3) 0.421
ascites = 1 (%) 10 ( 6.5) 0.567
hepato = 1 (%) 87 (56.5) 0.088
spiders = 1 (%) 45 (29.2) 0.985
edema (%) 0.877
0 131 (85.1)
0.5 13 ( 8.4)
1 10 ( 6.5)
bili (median [range]) 1.30 [0.30, 28.00] 0.842 nonnorm
chol (median [range]) 303.50 [120.00, 1775.00] 0.544 nonnorm
albumin (mean (SD)) 3.52 (0.40) 0.874
copper (median [range]) 73.00 [4.00, 558.00] 0.717 nonnorm
alk.phos (median [range]) 1283.00 [289.00, 13862.40] 0.812 nonnorm
ast (mean (SD)) 124.97 (58.93) 0.460
trig (median [range]) 113.00 [44.00, 432.00] 0.370 nonnorm
platelet (mean (SD)) 265.20 (90.73) 0.555
protime (mean (SD)) 10.80 (1.14) 0.197
stage (%) 0.201
1 4 ( 2.6)
2 32 (20.8)
3 64 (41.6)
4 54 (35.1)
Stratified by trt
1 2
n 158 154
time (mean (SD)) 2015.62 (1094.12) 1996.86 (1155.93)
status (%)
0 83 (52.5) 85 (55.2)
1 10 (6.3) 9 (5.8)
2 65 (41.1) 60 (39.0)
age (mean (SD)) 51.42 (11.01) 48.58 (9.96)
sex = f (%) 137 (86.7) 139 (90.3)
ascites = 1 (%) 14 (8.9) 10 (6.5)
hepato = 1 (%) 73 (46.2) 87 (56.5)
spiders = 1 (%) 45 (28.5) 45 (29.2)
edema (%)
0 132 (83.5) 131 (85.1)
0.5 16 (10.1) 13 (8.4)
1 10 (6.3) 10 (6.5)
bili (median [IQR]) 1.40 [0.80, 3.20] 1.30 [0.72, 3.60]
chol (median [IQR]) 315.50 [247.75, 417.00] 303.50 [254.25, 377.00]
albumin (mean (SD)) 3.52 (0.44) 3.52 (0.40)
copper (median [IQR]) 73.00 [40.00, 121.00] 73.00 [43.00, 139.00]
alk.phos (median [IQR]) 1214.50 [840.75, 2028.00] 1283.00 [922.50, 1949.75]
ast (mean (SD)) 120.21 (54.52) 124.97 (58.93)
trig (median [IQR]) 106.00 [84.50, 146.00] 113.00 [84.50, 155.00]
platelet (mean (SD)) 258.75 (100.32) 265.20 (90.73)
protime (mean (SD)) 10.65 (0.85) 10.80 (1.14)
stage (%)
1 12 (7.6) 4 (2.6)
2 35 (22.2) 32 (20.8)
3 56 (35.4) 64 (41.6)
4 55 (34.8) 54 (35.1)
Stratified by trt
p test
n
time (mean (SD)) 0.883
status (%) 0.884 exact
0
1
2
age (mean (SD)) 0.018
sex = f (%) 0.421
ascites = 1 (%) 0.567
hepato = 1 (%) 0.088
spiders = 1 (%) 0.985
edema (%) 0.877
0
0.5
1
bili (median [IQR]) 0.842 nonnorm
chol (median [IQR]) 0.544 nonnorm
albumin (mean (SD)) 0.874
copper (median [IQR]) 0.717 nonnorm
alk.phos (median [IQR]) 0.812 nonnorm
ast (mean (SD)) 0.460
trig (median [IQR]) 0.370 nonnorm
platelet (mean (SD)) 0.555
protime (mean (SD)) 0.197
stage (%) 0.205 exact
1
2
3
4
Stratified by trt
1 2
n 158 154
time (mean (SD)) 2015.62 (1094.12) 1996.86 (1155.93)
status (%)
0 83 (52.5) 85 (55.2)
1 10 (6.3) 9 (5.8)
2 65 (41.1) 60 (39.0)
age (mean (SD)) 51.42 (11.01) 48.58 (9.96)
sex = f (%) 137 (86.7) 139 (90.3)
ascites = 1 (%) 14 (8.9) 10 (6.5)
hepato = 1 (%) 73 (46.2) 87 (56.5)
spiders = 1 (%) 45 (28.5) 45 (29.2)
edema (%)
0 132 (83.5) 131 (85.1)
0.5 16 (10.1) 13 (8.4)
1 10 (6.3) 10 (6.5)
bili (median [IQR]) 1.40 [0.80, 3.20] 1.30 [0.72, 3.60]
chol (median [IQR]) 315.50 [247.75, 417.00] 303.50 [254.25, 377.00]
albumin (mean (SD)) 3.52 (0.44) 3.52 (0.40)
copper (median [IQR]) 73.00 [40.00, 121.00] 73.00 [43.00, 139.00]
alk.phos (median [IQR]) 1214.50 [840.75, 2028.00] 1283.00 [922.50, 1949.75]
ast (mean (SD)) 120.21 (54.52) 124.97 (58.93)
trig (median [IQR]) 106.00 [84.50, 146.00] 113.00 [84.50, 155.00]
platelet (mean (SD)) 258.75 (100.32) 265.20 (90.73)
protime (mean (SD)) 10.65 (0.85) 10.80 (1.14)
stage (%)
1 12 (7.6) 4 (2.6)
2 35 (22.2) 32 (20.8)
3 56 (35.4) 64 (41.6)
4 55 (34.8) 54 (35.1)
Stratified by trt
p test
n
time (mean (SD)) 0.883
status (%) 0.884 exact
0
1
2
age (mean (SD)) 0.018
sex = f (%) 0.421
ascites = 1 (%) 0.567
hepato = 1 (%) 0.088
spiders = 1 (%) 0.985
edema (%) 0.877
0
0.5
1
bili (median [IQR]) 0.842 nonnorm
chol (median [IQR]) 0.544 nonnorm
albumin (mean (SD)) 0.874
copper (median [IQR]) 0.717 nonnorm
alk.phos (median [IQR]) 0.812 nonnorm
ast (mean (SD)) 0.460
trig (median [IQR]) 0.370 nonnorm
platelet (mean (SD)) 0.555
protime (mean (SD)) 0.197
stage (%) 0.205 exact
1
2
3
4
Stratified by trt
level 1
n 158
time (mean (SD)) 2015.62 (1094.12)
status (%) 0 83 (52.5)
1 10 ( 6.3)
2 65 (41.1)
age (mean (SD)) 51.42 (11.01)
sex (%) m 21 (13.3)
f 137 (86.7)
ascites (%) 0 144 (91.1)
1 14 ( 8.9)
hepato (%) 0 85 (53.8)
1 73 (46.2)
spiders (%) 0 113 (71.5)
1 45 (28.5)
edema (%) 0 132 (83.5)
0.5 16 (10.1)
1 10 ( 6.3)
bili (median [IQR]) 1.40 [0.80, 3.20]
chol (median [IQR]) 315.50 [247.75, 417.00]
albumin (mean (SD)) 3.52 (0.44)
copper (median [IQR]) 73.00 [40.00, 121.00]
alk.phos (median [IQR]) 1214.50 [840.75, 2028.00]
ast (mean (SD)) 120.21 (54.52)
trig (median [IQR]) 106.00 [84.50, 146.00]
platelet (mean (SD)) 258.75 (100.32)
protime (mean (SD)) 10.65 (0.85)
stage (%) 1 12 ( 7.6)
2 35 (22.2)
3 56 (35.4)
4 55 (34.8)
Stratified by trt
2 p test
n 154
time (mean (SD)) 1996.86 (1155.93) 0.883
status (%) 85 (55.2) 0.884 exact
9 ( 5.8)
60 (39.0)
age (mean (SD)) 48.58 (9.96) 0.018
sex (%) 15 ( 9.7) 0.421
139 (90.3)
ascites (%) 144 (93.5) 0.567
10 ( 6.5)
hepato (%) 67 (43.5) 0.088
87 (56.5)
spiders (%) 109 (70.8) 0.985
45 (29.2)
edema (%) 131 (85.1) 0.877
13 ( 8.4)
10 ( 6.5)
bili (median [IQR]) 1.30 [0.72, 3.60] 0.842 nonnorm
chol (median [IQR]) 303.50 [254.25, 377.00] 0.544 nonnorm
albumin (mean (SD)) 3.52 (0.40) 0.874
copper (median [IQR]) 73.00 [43.00, 139.00] 0.717 nonnorm
alk.phos (median [IQR]) 1283.00 [922.50, 1949.75] 0.812 nonnorm
ast (mean (SD)) 124.97 (58.93) 0.460
trig (median [IQR]) 113.00 [84.50, 155.00] 0.370 nonnorm
platelet (mean (SD)) 265.20 (90.73) 0.555
protime (mean (SD)) 10.80 (1.14) 0.197
stage (%) 4 ( 2.6) 0.205 exact
32 (20.8)
64 (41.6)
54 (35.1)
Stratified by trt
level 1
n 158
time (mean (SD)) 2015.62 (1094.12)
status (%) 0 83 (52.5)
1 10 ( 6.3)
2 65 (41.1)
age (mean (SD)) 51.42 (11.01)
sex (%) m 21 (13.3)
f 137 (86.7)
ascites (%) 0 144 (91.1)
1 14 ( 8.9)
hepato (%) 0 85 (53.8)
1 73 (46.2)
spiders (%) 0 113 (71.5)
1 45 (28.5)
edema (%) 0 132 (83.5)
0.5 16 (10.1)
1 10 ( 6.3)
bili (median [IQR]) 1.40 [0.80, 3.20]
chol (median [IQR]) 315.50 [247.75, 417.00]
albumin (mean (SD)) 3.52 (0.44)
copper (median [IQR]) 73.00 [40.00, 121.00]
alk.phos (median [IQR]) 1214.50 [840.75, 2028.00]
ast (mean (SD)) 120.21 (54.52)
trig (median [IQR]) 106.00 [84.50, 146.00]
platelet (mean (SD)) 258.75 (100.32)
protime (mean (SD)) 10.65 (0.85)
stage (%) 1 12 ( 7.6)
2 35 (22.2)
3 56 (35.4)
4 55 (34.8)
Stratified by trt
2 p test
n 154
time (mean (SD)) 1996.86 (1155.93) 0.883
status (%) 85 (55.2) 0.884 exact
9 ( 5.8)
60 (39.0)
age (mean (SD)) 48.58 (9.96) 0.018
sex (%) 15 ( 9.7) 0.421
139 (90.3)
ascites (%) 144 (93.5) 0.567
10 ( 6.5)
hepato (%) 67 (43.5) 0.088
87 (56.5)
spiders (%) 109 (70.8) 0.985
45 (29.2)
edema (%) 131 (85.1) 0.877
13 ( 8.4)
10 ( 6.5)
bili (median [IQR]) 1.30 [0.72, 3.60] 0.842 nonnorm
chol (median [IQR]) 303.50 [254.25, 377.00] 0.544 nonnorm
albumin (mean (SD)) 3.52 (0.40) 0.874
copper (median [IQR]) 73.00 [43.00, 139.00] 0.717 nonnorm
alk.phos (median [IQR]) 1283.00 [922.50, 1949.75] 0.812 nonnorm
ast (mean (SD)) 124.97 (58.93) 0.460
trig (median [IQR]) 113.00 [84.50, 155.00] 0.370 nonnorm
platelet (mean (SD)) 265.20 (90.73) 0.555
protime (mean (SD)) 10.80 (1.14) 0.197
stage (%) 4 ( 2.6) 0.205 exact
32 (20.8)
64 (41.6)
54 (35.1)
"Stratified by trt"
"" "1"
"n" "158"
"time (mean (SD))" "2015.62 (1094.12)"
"status (%)" ""
" 0" "83 (52.5)"
" 1" "10 (6.3)"
" 2" "65 (41.1)"
"age (mean (SD))" "51.42 (11.01)"
"sex = f (%)" "137 (86.7)"
"ascites = 1 (%)" "14 (8.9)"
"hepato = 1 (%)" "73 (46.2)"
"spiders = 1 (%)" "45 (28.5)"
"edema (%)" ""
" 0" "132 (83.5)"
" 0.5" "16 (10.1)"
" 1" "10 (6.3)"
"bili (median [IQR])" "1.40 [0.80, 3.20]"
"chol (median [IQR])" "315.50 [247.75, 417.00]"
"albumin (mean (SD))" "3.52 (0.44)"
"copper (median [IQR])" "73.00 [40.00, 121.00]"
"alk.phos (median [IQR])" "1214.50 [840.75, 2028.00]"
"ast (mean (SD))" "120.21 (54.52)"
"trig (median [IQR])" "106.00 [84.50, 146.00]"
"platelet (mean (SD))" "258.75 (100.32)"
"protime (mean (SD))" "10.65 (0.85)"
"stage (%)" ""
" 1" "12 (7.6)"
" 2" "35 (22.2)"
" 3" "56 (35.4)"
" 4" "55 (34.8)"
"Stratified by trt"
"" "2" "p" "test"
"n" "154" "" ""
"time (mean (SD))" "1996.86 (1155.93)" "0.883" ""
"status (%)" "" "0.884" "exact"
" 0" "85 (55.2)" "" ""
" 1" "9 (5.8)" "" ""
" 2" "60 (39.0)" "" ""
"age (mean (SD))" "48.58 (9.96)" "0.018" ""
"sex = f (%)" "139 (90.3)" "0.421" ""
"ascites = 1 (%)" "10 (6.5)" "0.567" ""
"hepato = 1 (%)" "87 (56.5)" "0.088" ""
"spiders = 1 (%)" "45 (29.2)" "0.985" ""
"edema (%)" "" "0.877" ""
" 0" "131 (85.1)" "" ""
" 0.5" "13 (8.4)" "" ""
" 1" "10 (6.5)" "" ""
"bili (median [IQR])" "1.30 [0.72, 3.60]" "0.842" "nonnorm"
"chol (median [IQR])" "303.50 [254.25, 377.00]" "0.544" "nonnorm"
"albumin (mean (SD))" "3.52 (0.40)" "0.874" ""
"copper (median [IQR])" "73.00 [43.00, 139.00]" "0.717" "nonnorm"
"alk.phos (median [IQR])" "1283.00 [922.50, 1949.75]" "0.812" "nonnorm"
"ast (mean (SD))" "124.97 (58.93)" "0.460" ""
"trig (median [IQR])" "113.00 [84.50, 155.00]" "0.370" "nonnorm"
"platelet (mean (SD))" "265.20 (90.73)" "0.555" ""
"protime (mean (SD))" "10.80 (1.14)" "0.197" ""
"stage (%)" "" "0.205" "exact"
" 1" "4 (2.6)" "" ""
" 2" "32 (20.8)" "" ""
" 3" "64 (41.6)" "" ""
" 4" "54 (35.1)" "" ""
"Stratified by trt"
"" "1"
"n" "158"
"time (mean (SD))" "2015.62 (1094.12)"
"status (%)" ""
" 0" "83 (52.5)"
" 1" "10 (6.3)"
" 2" "65 (41.1)"
"age (mean (SD))" "51.42 (11.01)"
"sex = f (%)" "137 (86.7)"
"ascites = 1 (%)" "14 (8.9)"
"hepato = 1 (%)" "73 (46.2)"
"spiders = 1 (%)" "45 (28.5)"
"edema (%)" ""
" 0" "132 (83.5)"
" 0.5" "16 (10.1)"
" 1" "10 (6.3)"
"bili (median [IQR])" "1.40 [0.80, 3.20]"
"chol (median [IQR])" "315.50 [247.75, 417.00]"
"albumin (mean (SD))" "3.52 (0.44)"
"copper (median [IQR])" "73.00 [40.00, 121.00]"
"alk.phos (median [IQR])" "1214.50 [840.75, 2028.00]"
"ast (mean (SD))" "120.21 (54.52)"
"trig (median [IQR])" "106.00 [84.50, 146.00]"
"platelet (mean (SD))" "258.75 (100.32)"
"protime (mean (SD))" "10.65 (0.85)"
"stage (%)" ""
" 1" "12 (7.6)"
" 2" "35 (22.2)"
" 3" "56 (35.4)"
" 4" "55 (34.8)"
"Stratified by trt"
"" "2" "p" "test"
"n" "154" "" ""
"time (mean (SD))" "1996.86 (1155.93)" "0.883" ""
"status (%)" "" "0.884" "exact"
" 0" "85 (55.2)" "" ""
" 1" "9 (5.8)" "" ""
" 2" "60 (39.0)" "" ""
"age (mean (SD))" "48.58 (9.96)" "0.018" ""
"sex = f (%)" "139 (90.3)" "0.421" ""
"ascites = 1 (%)" "10 (6.5)" "0.567" ""
"hepato = 1 (%)" "87 (56.5)" "0.088" ""
"spiders = 1 (%)" "45 (29.2)" "0.985" ""
"edema (%)" "" "0.877" ""
" 0" "131 (85.1)" "" ""
" 0.5" "13 (8.4)" "" ""
" 1" "10 (6.5)" "" ""
"bili (median [IQR])" "1.30 [0.72, 3.60]" "0.842" "nonnorm"
"chol (median [IQR])" "303.50 [254.25, 377.00]" "0.544" "nonnorm"
"albumin (mean (SD))" "3.52 (0.40)" "0.874" ""
"copper (median [IQR])" "73.00 [43.00, 139.00]" "0.717" "nonnorm"
"alk.phos (median [IQR])" "1283.00 [922.50, 1949.75]" "0.812" "nonnorm"
"ast (mean (SD))" "124.97 (58.93)" "0.460" ""
"trig (median [IQR])" "113.00 [84.50, 155.00]" "0.370" "nonnorm"
"platelet (mean (SD))" "265.20 (90.73)" "0.555" ""
"protime (mean (SD))" "10.80 (1.14)" "0.197" ""
"stage (%)" "" "0.205" "exact"
" 1" "4 (2.6)" "" ""
" 2" "32 (20.8)" "" ""
" 3" "64 (41.6)" "" ""
" 4" "54 (35.1)" "" ""
Stratified by trt:sex
1:m 2:m 1:f
n 21 15 137
time (mean (SD)) 1793.48 (1244.70) 2156.33 (1428.56) 2049.67 (1070.20)
age (mean (SD)) 55.57 (12.61) 57.09 (10.07) 50.78 (10.65)
protime (mean (SD)) 10.84 (0.94) 11.23 (0.97) 10.62 (0.84)
Stratified by trt:sex
2:f p test
n 139
time (mean (SD)) 1979.65 (1127.52) 0.730
age (mean (SD)) 47.66 (9.54) <0.001
protime (mean (SD)) 10.75 (1.15) 0.137
Stratified by trt:sex
1:m 2:m 1:f
n 21 15 137
time (mean (SD)) 1793.48 (1244.70) 2156.33 (1428.56) 2049.67 (1070.20)
age (mean (SD)) 55.57 (12.61) 57.09 (10.07) 50.78 (10.65)
protime (mean (SD)) 10.84 (0.94) 11.23 (0.97) 10.62 (0.84)
Stratified by trt:sex
2:f p test
n 139
time (mean (SD)) 1979.65 (1127.52) 0.730
age (mean (SD)) 47.66 (9.54) <0.001
protime (mean (SD)) 10.75 (1.15) 0.137
Stratified by trt:sex
1:m 2:m 1:f 2:f p test
n 21 15 137 139
status (%) 0.033
0 4 (19.0) 7 ( 46.7) 79 ( 57.7) 78 ( 56.1)
1 3 (14.3) 0 ( 0.0) 7 ( 5.1) 9 ( 6.5)
2 14 (66.7) 8 ( 53.3) 51 ( 37.2) 52 ( 37.4)
trt = 2 (%) 0 ( 0.0) 15 (100.0) 0 ( 0.0) 139 (100.0) <0.001
sex = f (%) 0 ( 0.0) 0 ( 0.0) 137 (100.0) 139 (100.0) <0.001
Stratified by trt:sex
1:m 2:m 1:f 2:f p test
n 21 15 137 139
status (%) 0.033
0 4 (19.0) 7 ( 46.7) 79 ( 57.7) 78 ( 56.1)
1 3 (14.3) 0 ( 0.0) 7 ( 5.1) 9 ( 6.5)
2 14 (66.7) 8 ( 53.3) 51 ( 37.2) 52 ( 37.4)
trt = 2 (%) 0 ( 0.0) 15 (100.0) 0 ( 0.0) 139 (100.0) <0.001
sex = f (%) 0 ( 0.0) 0 ( 0.0) 137 (100.0) 139 (100.0) <0.001
"Stratified by trt"
"" "Overall"
"n" "418"
"time (mean (SD))" "1917.78 (1104.67)"
"status (%)" ""
" 0" "232 (55.5)"
" 1" "25 (6.0)"
" 2" "161 (38.5)"
"age (mean (SD))" "50.74 (10.45)"
"sex = f (%)" "374 (89.5)"
"ascites = 1 (%)" "24 (7.7)"
"hepato = 1 (%)" "160 (51.3)"
"spiders = 1 (%)" "90 (28.8)"
"edema (%)" ""
" 0" "354 (84.7)"
" 0.5" "44 (10.5)"
" 1" "20 (4.8)"
"bili (median [IQR])" "1.40 [0.80, 3.40]"
"chol (median [IQR])" "309.50 [249.50, 400.00]"
"albumin (mean (SD))" "3.50 (0.42)"
"copper (median [IQR])" "73.00 [41.25, 123.00]"
"alk.phos (median [IQR])" "1259.00 [871.50, 1980.00]"
"ast (mean (SD))" "122.56 (56.70)"
"trig (median [IQR])" "108.00 [84.25, 151.00]"
"platelet (mean (SD))" "257.02 (98.33)"
"protime (mean (SD))" "10.73 (1.02)"
"stage (%)" ""
" 1" "21 (5.1)"
" 2" "92 (22.3)"
" 3" "155 (37.6)"
" 4" "144 (35.0)"
"Stratified by trt"
"" "1"
"n" "158"
"time (mean (SD))" "2015.62 (1094.12)"
"status (%)" ""
" 0" "83 (52.5)"
" 1" "10 (6.3)"
" 2" "65 (41.1)"
"age (mean (SD))" "51.42 (11.01)"
"sex = f (%)" "137 (86.7)"
"ascites = 1 (%)" "14 (8.9)"
"hepato = 1 (%)" "73 (46.2)"
"spiders = 1 (%)" "45 (28.5)"
"edema (%)" ""
" 0" "132 (83.5)"
" 0.5" "16 (10.1)"
" 1" "10 (6.3)"
"bili (median [IQR])" "1.40 [0.80, 3.20]"
"chol (median [IQR])" "315.50 [247.75, 417.00]"
"albumin (mean (SD))" "3.52 (0.44)"
"copper (median [IQR])" "73.00 [40.00, 121.00]"
"alk.phos (median [IQR])" "1214.50 [840.75, 2028.00]"
"ast (mean (SD))" "120.21 (54.52)"
"trig (median [IQR])" "106.00 [84.50, 146.00]"
"platelet (mean (SD))" "258.75 (100.32)"
"protime (mean (SD))" "10.65 (0.85)"
"stage (%)" ""
" 1" "12 (7.6)"
" 2" "35 (22.2)"
" 3" "56 (35.4)"
" 4" "55 (34.8)"
"Stratified by trt"
"" "2" "p" "test"
"n" "154" "" ""
"time (mean (SD))" "1996.86 (1155.93)" "0.883" ""
"status (%)" "" "0.884" "exact"
" 0" "85 (55.2)" "" ""
" 1" "9 (5.8)" "" ""
" 2" "60 (39.0)" "" ""
"age (mean (SD))" "48.58 (9.96)" "0.018" ""
"sex = f (%)" "139 (90.3)" "0.421" ""
"ascites = 1 (%)" "10 (6.5)" "0.567" ""
"hepato = 1 (%)" "87 (56.5)" "0.088" ""
"spiders = 1 (%)" "45 (29.2)" "0.985" ""
"edema (%)" "" "0.877" ""
" 0" "131 (85.1)" "" ""
" 0.5" "13 (8.4)" "" ""
" 1" "10 (6.5)" "" ""
"bili (median [IQR])" "1.30 [0.72, 3.60]" "0.842" "nonnorm"
"chol (median [IQR])" "303.50 [254.25, 377.00]" "0.544" "nonnorm"
"albumin (mean (SD))" "3.52 (0.40)" "0.874" ""
"copper (median [IQR])" "73.00 [43.00, 139.00]" "0.717" "nonnorm"
"alk.phos (median [IQR])" "1283.00 [922.50, 1949.75]" "0.812" "nonnorm"
"ast (mean (SD))" "124.97 (58.93)" "0.460" ""
"trig (median [IQR])" "113.00 [84.50, 155.00]" "0.370" "nonnorm"
"platelet (mean (SD))" "265.20 (90.73)" "0.555" ""
"protime (mean (SD))" "10.80 (1.14)" "0.197" ""
"stage (%)" "" "0.205" "exact"
" 1" "4 (2.6)" "" ""
" 2" "32 (20.8)" "" ""
" 3" "64 (41.6)" "" ""
" 4" "54 (35.1)" "" ""
"Stratified by trt"
"" "SMD"
"n" ""
"time (mean (SD))" "0.017"
"status (%)" "0.054"
" 0" ""
" 1" ""
" 2" ""
"age (mean (SD))" "0.270"
"sex = f (%)" "0.111"
"ascites = 1 (%)" "0.089"
"hepato = 1 (%)" "0.207"
"spiders = 1 (%)" "0.016"
"edema (%)" "0.058"
" 0" ""
" 0.5" ""
" 1" ""
"bili (median [IQR])" "0.171"
"chol (median [IQR])" "0.038"
"albumin (mean (SD))" "0.018"
"copper (median [IQR])" "<0.001"
"alk.phos (median [IQR])" "0.037"
"ast (mean (SD))" "0.084"
"trig (median [IQR])" "0.017"
"platelet (mean (SD))" "0.067"
"protime (mean (SD))" "0.146"
"stage (%)" "0.246"
" 1" ""
" 2" ""
" 3" ""
" 4" ""
"Stratified by trt"
"" "Overall"
"n" "418"
"time (mean (SD))" "1917.78 (1104.67)"
"status (%)" ""
" 0" "232 (55.5)"
" 1" "25 (6.0)"
" 2" "161 (38.5)"
"age (mean (SD))" "50.74 (10.45)"
"sex = f (%)" "374 (89.5)"
"ascites = 1 (%)" "24 (7.7)"
"hepato = 1 (%)" "160 (51.3)"
"spiders = 1 (%)" "90 (28.8)"
"edema (%)" ""
" 0" "354 (84.7)"
" 0.5" "44 (10.5)"
" 1" "20 (4.8)"
"bili (median [IQR])" "1.40 [0.80, 3.40]"
"chol (median [IQR])" "309.50 [249.50, 400.00]"
"albumin (mean (SD))" "3.50 (0.42)"
"copper (median [IQR])" "73.00 [41.25, 123.00]"
"alk.phos (median [IQR])" "1259.00 [871.50, 1980.00]"
"ast (mean (SD))" "122.56 (56.70)"
"trig (median [IQR])" "108.00 [84.25, 151.00]"
"platelet (mean (SD))" "257.02 (98.33)"
"protime (mean (SD))" "10.73 (1.02)"
"stage (%)" ""
" 1" "21 (5.1)"
" 2" "92 (22.3)"
" 3" "155 (37.6)"
" 4" "144 (35.0)"
"Stratified by trt"
"" "1"
"n" "158"
"time (mean (SD))" "2015.62 (1094.12)"
"status (%)" ""
" 0" "83 (52.5)"
" 1" "10 (6.3)"
" 2" "65 (41.1)"
"age (mean (SD))" "51.42 (11.01)"
"sex = f (%)" "137 (86.7)"
"ascites = 1 (%)" "14 (8.9)"
"hepato = 1 (%)" "73 (46.2)"
"spiders = 1 (%)" "45 (28.5)"
"edema (%)" ""
" 0" "132 (83.5)"
" 0.5" "16 (10.1)"
" 1" "10 (6.3)"
"bili (median [IQR])" "1.40 [0.80, 3.20]"
"chol (median [IQR])" "315.50 [247.75, 417.00]"
"albumin (mean (SD))" "3.52 (0.44)"
"copper (median [IQR])" "73.00 [40.00, 121.00]"
"alk.phos (median [IQR])" "1214.50 [840.75, 2028.00]"
"ast (mean (SD))" "120.21 (54.52)"
"trig (median [IQR])" "106.00 [84.50, 146.00]"
"platelet (mean (SD))" "258.75 (100.32)"
"protime (mean (SD))" "10.65 (0.85)"
"stage (%)" ""
" 1" "12 (7.6)"
" 2" "35 (22.2)"
" 3" "56 (35.4)"
" 4" "55 (34.8)"
"Stratified by trt"
"" "2" "p" "test"
"n" "154" "" ""
"time (mean (SD))" "1996.86 (1155.93)" "0.883" ""
"status (%)" "" "0.884" "exact"
" 0" "85 (55.2)" "" ""
" 1" "9 (5.8)" "" ""
" 2" "60 (39.0)" "" ""
"age (mean (SD))" "48.58 (9.96)" "0.018" ""
"sex = f (%)" "139 (90.3)" "0.421" ""
"ascites = 1 (%)" "10 (6.5)" "0.567" ""
"hepato = 1 (%)" "87 (56.5)" "0.088" ""
"spiders = 1 (%)" "45 (29.2)" "0.985" ""
"edema (%)" "" "0.877" ""
" 0" "131 (85.1)" "" ""
" 0.5" "13 (8.4)" "" ""
" 1" "10 (6.5)" "" ""
"bili (median [IQR])" "1.30 [0.72, 3.60]" "0.842" "nonnorm"
"chol (median [IQR])" "303.50 [254.25, 377.00]" "0.544" "nonnorm"
"albumin (mean (SD))" "3.52 (0.40)" "0.874" ""
"copper (median [IQR])" "73.00 [43.00, 139.00]" "0.717" "nonnorm"
"alk.phos (median [IQR])" "1283.00 [922.50, 1949.75]" "0.812" "nonnorm"
"ast (mean (SD))" "124.97 (58.93)" "0.460" ""
"trig (median [IQR])" "113.00 [84.50, 155.00]" "0.370" "nonnorm"
"platelet (mean (SD))" "265.20 (90.73)" "0.555" ""
"protime (mean (SD))" "10.80 (1.14)" "0.197" ""
"stage (%)" "" "0.205" "exact"
" 1" "4 (2.6)" "" ""
" 2" "32 (20.8)" "" ""
" 3" "64 (41.6)" "" ""
" 4" "54 (35.1)" "" ""
"Stratified by trt"
"" "SMD"
"n" ""
"time (mean (SD))" "0.017"
"status (%)" "0.054"
" 0" ""
" 1" ""
" 2" ""
"age (mean (SD))" "0.270"
"sex = f (%)" "0.111"
"ascites = 1 (%)" "0.089"
"hepato = 1 (%)" "0.207"
"spiders = 1 (%)" "0.016"
"edema (%)" "0.058"
" 0" ""
" 0.5" ""
" 1" ""
"bili (median [IQR])" "0.171"
"chol (median [IQR])" "0.038"
"albumin (mean (SD))" "0.018"
"copper (median [IQR])" "<0.001"
"alk.phos (median [IQR])" "0.037"
"ast (mean (SD))" "0.084"
"trig (median [IQR])" "0.017"
"platelet (mean (SD))" "0.067"
"protime (mean (SD))" "0.146"
"stage (%)" "0.246"
" 1" ""
" 2" ""
" 3" ""
" 4" ""
Stratified by trt:sex
Overall 1:m 2:m
n 418 21 15
time (mean (SD)) 1917.78 (1104.67) 1793.48 (1244.70) 2156.33 (1428.56)
status (%)
0 232 (55.5) 4 (19.0) 7 (46.7)
1 25 ( 6.0) 3 (14.3) 0 ( 0.0)
2 161 (38.5) 14 (66.7) 8 (53.3)
age (mean (SD)) 50.74 (10.45) 55.57 (12.61) 57.09 (10.07)
sex = f (%) 374 (89.5) 0 ( 0.0) 0 ( 0.0)
ascites = 1 (%) 24 ( 7.7) 1 ( 4.8) 2 (13.3)
hepato = 1 (%) 160 (51.3) 12 (57.1) 9 (60.0)
spiders = 1 (%) 90 (28.8) 3 (14.3) 1 ( 6.7)
edema (%)
0 354 (84.7) 17 (81.0) 12 (80.0)
0.5 44 (10.5) 3 (14.3) 1 ( 6.7)
1 20 ( 4.8) 1 ( 4.8) 2 (13.3)
bili (mean (SD)) 3.22 (4.41) 2.98 (2.11) 2.72 (2.46)
chol (mean (SD)) 369.51 (231.94) 403.43 (204.95) 301.00 (111.32)
albumin (mean (SD)) 3.50 (0.42) 3.63 (0.43) 3.50 (0.49)
copper (mean (SD)) 97.65 (85.61) 174.90 (105.33) 125.40 (89.18)
alk.phos (mean (SD)) 1982.66 (2140.39) 2486.16 (2385.32) 1734.45 (2478.07)
ast (mean (SD)) 122.56 (56.70) 128.71 (48.74) 112.58 (44.38)
trig (mean (SD)) 124.70 (65.15) 145.81 (56.62) 114.86 (39.59)
platelet (mean (SD)) 257.02 (98.33) 232.65 (97.38) 240.13 (73.93)
protime (mean (SD)) 10.73 (1.02) 10.84 (0.94) 11.23 (0.97)
stage (%)
1 21 ( 5.1) 2 ( 9.5) 1 ( 6.7)
2 92 (22.3) 4 (19.0) 2 (13.3)
3 155 (37.6) 7 (33.3) 5 (33.3)
4 144 (35.0) 8 (38.1) 7 (46.7)
Stratified by trt:sex
1:f 2:f p test SMD
n 137 139
time (mean (SD)) 2049.67 (1070.20) 1979.65 (1127.52) 0.730 0.156
status (%) 0.033 0.577
0 79 ( 57.7) 78 ( 56.1)
1 7 ( 5.1) 9 ( 6.5)
2 51 ( 37.2) 52 ( 37.4)
age (mean (SD)) 50.78 (10.65) 47.66 (9.54) <0.001 0.521
sex = f (%) 137 (100.0) 139 (100.0) <0.001 NaN
ascites = 1 (%) 13 ( 9.5) 8 ( 5.8) 0.516 0.176
hepato = 1 (%) 61 ( 44.5) 78 ( 56.1) 0.208 0.160
spiders = 1 (%) 42 ( 30.7) 44 ( 31.7) 0.089 0.402
edema (%) 0.906 0.212
0 115 ( 83.9) 119 ( 85.6)
0.5 13 ( 9.5) 12 ( 8.6)
1 9 ( 6.6) 8 ( 5.8)
bili (mean (SD)) 2.86 (3.81) 3.75 (5.50) 0.394 0.135
chol (mean (SD)) 358.24 (210.46) 381.73 (262.26) 0.512 0.295
albumin (mean (SD)) 3.50 (0.44) 3.53 (0.39) 0.585 0.164
copper (mean (SD)) 85.71 (82.27) 94.64 (79.25) <0.001 0.542
alk.phos (mean (SD)) 1950.04 (2151.35) 1965.52 (2066.15) 0.706 0.163
ast (mean (SD)) 118.91 (55.40) 126.30 (60.27) 0.598 0.182
trig (mean (SD)) 120.28 (73.41) 126.38 (60.22) 0.370 0.294
platelet (mean (SD)) 262.59 (100.53) 267.95 (92.20) 0.362 0.234
protime (mean (SD)) 10.62 (0.84) 10.75 (1.15) 0.137 0.328
stage (%) 0.646 0.277
1 10 ( 7.3) 3 ( 2.2)
2 31 ( 22.6) 30 ( 21.6)
3 49 ( 35.8) 59 ( 42.4)
4 47 ( 34.3) 47 ( 33.8)
Stratified by trt:sex
Overall 1:m 2:m
n 418 21 15
time (mean (SD)) 1917.78 (1104.67) 1793.48 (1244.70) 2156.33 (1428.56)
status (%)
0 232 (55.5) 4 (19.0) 7 (46.7)
1 25 ( 6.0) 3 (14.3) 0 ( 0.0)
2 161 (38.5) 14 (66.7) 8 (53.3)
age (mean (SD)) 50.74 (10.45) 55.57 (12.61) 57.09 (10.07)
sex = f (%) 374 (89.5) 0 ( 0.0) 0 ( 0.0)
ascites = 1 (%) 24 ( 7.7) 1 ( 4.8) 2 (13.3)
hepato = 1 (%) 160 (51.3) 12 (57.1) 9 (60.0)
spiders = 1 (%) 90 (28.8) 3 (14.3) 1 ( 6.7)
edema (%)
0 354 (84.7) 17 (81.0) 12 (80.0)
0.5 44 (10.5) 3 (14.3) 1 ( 6.7)
1 20 ( 4.8) 1 ( 4.8) 2 (13.3)
bili (mean (SD)) 3.22 (4.41) 2.98 (2.11) 2.72 (2.46)
chol (mean (SD)) 369.51 (231.94) 403.43 (204.95) 301.00 (111.32)
albumin (mean (SD)) 3.50 (0.42) 3.63 (0.43) 3.50 (0.49)
copper (mean (SD)) 97.65 (85.61) 174.90 (105.33) 125.40 (89.18)
alk.phos (mean (SD)) 1982.66 (2140.39) 2486.16 (2385.32) 1734.45 (2478.07)
ast (mean (SD)) 122.56 (56.70) 128.71 (48.74) 112.58 (44.38)
trig (mean (SD)) 124.70 (65.15) 145.81 (56.62) 114.86 (39.59)
platelet (mean (SD)) 257.02 (98.33) 232.65 (97.38) 240.13 (73.93)
protime (mean (SD)) 10.73 (1.02) 10.84 (0.94) 11.23 (0.97)
stage (%)
1 21 ( 5.1) 2 ( 9.5) 1 ( 6.7)
2 92 (22.3) 4 (19.0) 2 (13.3)
3 155 (37.6) 7 (33.3) 5 (33.3)
4 144 (35.0) 8 (38.1) 7 (46.7)
Stratified by trt:sex
1:f 2:f p test SMD
n 137 139
time (mean (SD)) 2049.67 (1070.20) 1979.65 (1127.52) 0.730 0.156
status (%) 0.033 0.577
0 79 ( 57.7) 78 ( 56.1)
1 7 ( 5.1) 9 ( 6.5)
2 51 ( 37.2) 52 ( 37.4)
age (mean (SD)) 50.78 (10.65) 47.66 (9.54) <0.001 0.521
sex = f (%) 137 (100.0) 139 (100.0) <0.001 NaN
ascites = 1 (%) 13 ( 9.5) 8 ( 5.8) 0.516 0.176
hepato = 1 (%) 61 ( 44.5) 78 ( 56.1) 0.208 0.160
spiders = 1 (%) 42 ( 30.7) 44 ( 31.7) 0.089 0.402
edema (%) 0.906 0.212
0 115 ( 83.9) 119 ( 85.6)
0.5 13 ( 9.5) 12 ( 8.6)
1 9 ( 6.6) 8 ( 5.8)
bili (mean (SD)) 2.86 (3.81) 3.75 (5.50) 0.394 0.135
chol (mean (SD)) 358.24 (210.46) 381.73 (262.26) 0.512 0.295
albumin (mean (SD)) 3.50 (0.44) 3.53 (0.39) 0.585 0.164
copper (mean (SD)) 85.71 (82.27) 94.64 (79.25) <0.001 0.542
alk.phos (mean (SD)) 1950.04 (2151.35) 1965.52 (2066.15) 0.706 0.163
ast (mean (SD)) 118.91 (55.40) 126.30 (60.27) 0.598 0.182
trig (mean (SD)) 120.28 (73.41) 126.38 (60.22) 0.370 0.294
platelet (mean (SD)) 262.59 (100.53) 267.95 (92.20) 0.362 0.234
protime (mean (SD)) 10.62 (0.84) 10.75 (1.15) 0.137 0.328
stage (%) 0.646 0.277
1 10 ( 7.3) 3 ( 2.2)
2 31 ( 22.6) 30 ( 21.6)
3 49 ( 35.8) 59 ( 42.4)
4 47 ( 34.3) 47 ( 33.8)
Stratified by trt:sex
Overall 1:m 2:m
n 418 21 15
time (mean (SD)) 1917.78 (1104.67) 1793.48 (1244.70) 2156.33 (1428.56)
age (mean (SD)) 50.74 (10.45) 55.57 (12.61) 57.09 (10.07)
protime (mean (SD)) 10.73 (1.02) 10.84 (0.94) 11.23 (0.97)
Stratified by trt:sex
1:f 2:f p test SMD
n 137 139
time (mean (SD)) 2049.67 (1070.20) 1979.65 (1127.52) 0.730 0.156
age (mean (SD)) 50.78 (10.65) 47.66 (9.54) <0.001 0.521
protime (mean (SD)) 10.62 (0.84) 10.75 (1.15) 0.137 0.328
Stratified by trt:sex
Overall 1:m 2:m
n 418 21 15
time (mean (SD)) 1917.78 (1104.67) 1793.48 (1244.70) 2156.33 (1428.56)
age (mean (SD)) 50.74 (10.45) 55.57 (12.61) 57.09 (10.07)
protime (mean (SD)) 10.73 (1.02) 10.84 (0.94) 11.23 (0.97)
Stratified by trt:sex
1:f 2:f p test SMD
n 137 139
time (mean (SD)) 2049.67 (1070.20) 1979.65 (1127.52) 0.730 0.156
age (mean (SD)) 50.78 (10.65) 47.66 (9.54) <0.001 0.521
protime (mean (SD)) 10.62 (0.84) 10.75 (1.15) 0.137 0.328
Stratified by trt:sex
Overall 1:m 2:m 1:f 2:f
n 418 21 15 137 139
status (%)
0 232 (55.5) 4 (19.0) 7 ( 46.7) 79 ( 57.7) 78 ( 56.1)
1 25 ( 6.0) 3 (14.3) 0 ( 0.0) 7 ( 5.1) 9 ( 6.5)
2 161 (38.5) 14 (66.7) 8 ( 53.3) 51 ( 37.2) 52 ( 37.4)
trt = 2 (%) 154 (49.4) 0 ( 0.0) 15 (100.0) 0 ( 0.0) 139 (100.0)
sex = f (%) 374 (89.5) 0 ( 0.0) 0 ( 0.0) 137 (100.0) 139 (100.0)
Stratified by trt:sex
p test SMD
n
status (%) 0.033 0.577
0
1
2
trt = 2 (%) <0.001 NaN
sex = f (%) <0.001 NaN
Stratified by trt:sex
Overall 1:m 2:m 1:f 2:f
n 418 21 15 137 139
status (%)
0 232 (55.5) 4 (19.0) 7 ( 46.7) 79 ( 57.7) 78 ( 56.1)
1 25 ( 6.0) 3 (14.3) 0 ( 0.0) 7 ( 5.1) 9 ( 6.5)
2 161 (38.5) 14 (66.7) 8 ( 53.3) 51 ( 37.2) 52 ( 37.4)
trt = 2 (%) 154 (49.4) 0 ( 0.0) 15 (100.0) 0 ( 0.0) 139 (100.0)
sex = f (%) 374 (89.5) 0 ( 0.0) 0 ( 0.0) 137 (100.0) 139 (100.0)
Stratified by trt:sex
p test SMD
n
status (%) 0.033 0.577
0
1
2
trt = 2 (%) <0.001 NaN
sex = f (%) <0.001 NaN
"Stratified by trt"
"" "Overall"
"n" "4,18"
"time (mean (SD))" "19,17D78 (11,04D67)"
"status (%)" ""
" 0" "232 (55D5)"
" 1" "25 (6D0)"
" 2" "161 (38D5)"
"age (mean (SD))" "50D74 (10D45)"
"sex = f (%)" "374 (89D5)"
"ascites = 1 (%)" "24 (7D7)"
"hepato = 1 (%)" "160 (51D3)"
"spiders = 1 (%)" "90 (28D8)"
"edema (%)" ""
" 0" "354 (84D7)"
" 0.5" "44 (10D5)"
" 1" "20 (4D8)"
"bili (median [IQR])" "1D40 [0D80, 3D40]"
"chol (median [IQR])" "3,09D50 [2,49D50, 4,00D00]"
"albumin (mean (SD))" "3D50 (0D42)"
"copper (median [IQR])" "73D00 [41D25, 1,23D00]"
"alk.phos (median [IQR])" "12,59D00 [8,71D50, 19,80D00]"
"ast (mean (SD))" "1,22D56 (56D70)"
"trig (median [IQR])" "1,08D00 [84D25, 1,51D00]"
"platelet (mean (SD))" "2,57D02 (98D33)"
"protime (mean (SD))" "10D73 (1D02)"
"stage (%)" ""
" 1" "21 (5D1)"
" 2" "92 (22D3)"
" 3" "155 (37D6)"
" 4" "144 (35D0)"
"Stratified by trt"
"" "1"
"n" "1,58"
"time (mean (SD))" "20,15D62 (10,94D12)"
"status (%)" ""
" 0" "83 (52D5)"
" 1" "10 (6D3)"
" 2" "65 (41D1)"
"age (mean (SD))" "51D42 (11D01)"
"sex = f (%)" "137 (86D7)"
"ascites = 1 (%)" "14 (8D9)"
"hepato = 1 (%)" "73 (46D2)"
"spiders = 1 (%)" "45 (28D5)"
"edema (%)" ""
" 0" "132 (83D5)"
" 0.5" "16 (10D1)"
" 1" "10 (6D3)"
"bili (median [IQR])" "1D40 [0D80, 3D20]"
"chol (median [IQR])" "3,15D50 [2,47D75, 4,17D00]"
"albumin (mean (SD))" "3D52 (0D44)"
"copper (median [IQR])" "73D00 [40D00, 1,21D00]"
"alk.phos (median [IQR])" "12,14D50 [8,40D75, 20,28D00]"
"ast (mean (SD))" "1,20D21 (54D52)"
"trig (median [IQR])" "1,06D00 [84D50, 1,46D00]"
"platelet (mean (SD))" "2,58D75 (1,00D32)"
"protime (mean (SD))" "10D65 (0D85)"
"stage (%)" ""
" 1" "12 (7D6)"
" 2" "35 (22D2)"
" 3" "56 (35D4)"
" 4" "55 (34D8)"
"Stratified by trt"
"" "2" "p" "test"
"n" "1,54" "" ""
"time (mean (SD))" "19,96D86 (11,55D93)" "0D883" ""
"status (%)" "" "0D884" "exact"
" 0" "85 (55D2)" "" ""
" 1" "9 (5D8)" "" ""
" 2" "60 (39D0)" "" ""
"age (mean (SD))" "48D58 (9D96)" "0D018" ""
"sex = f (%)" "139 (90D3)" "0D421" ""
"ascites = 1 (%)" "10 (6D5)" "0D567" ""
"hepato = 1 (%)" "87 (56D5)" "0D088" ""
"spiders = 1 (%)" "45 (29D2)" "0D985" ""
"edema (%)" "" "0D877" ""
" 0" "131 (85D1)" "" ""
" 0.5" "13 (8D4)" "" ""
" 1" "10 (6D5)" "" ""
"bili (median [IQR])" "1D30 [0D72, 3D60]" "0D842" "nonnorm"
"chol (median [IQR])" "3,03D50 [2,54D25, 3,77D00]" "0D544" "nonnorm"
"albumin (mean (SD))" "3D52 (0D40)" "0D874" ""
"copper (median [IQR])" "73D00 [43D00, 1,39D00]" "0D717" "nonnorm"
"alk.phos (median [IQR])" "12,83D00 [9,22D50, 19,49D75]" "0D812" "nonnorm"
"ast (mean (SD))" "1,24D97 (58D93)" "0D460" ""
"trig (median [IQR])" "1,13D00 [84D50, 1,55D00]" "0D370" "nonnorm"
"platelet (mean (SD))" "2,65D20 (90D73)" "0D555" ""
"protime (mean (SD))" "10D80 (1D14)" "0D197" ""
"stage (%)" "" "0D205" "exact"
" 1" "4 (2D6)" "" ""
" 2" "32 (20D8)" "" ""
" 3" "64 (41D6)" "" ""
" 4" "54 (35D1)" "" ""
"Stratified by trt"
"" "SMD"
"n" ""
"time (mean (SD))" "0D017"
"status (%)" "0D054"
" 0" ""
" 1" ""
" 2" ""
"age (mean (SD))" "0D270"
"sex = f (%)" "0D111"
"ascites = 1 (%)" "0D089"
"hepato = 1 (%)" "0D207"
"spiders = 1 (%)" "0D016"
"edema (%)" "0D058"
" 0" ""
" 0.5" ""
" 1" ""
"bili (median [IQR])" "0D171"
"chol (median [IQR])" "0D038"
"albumin (mean (SD))" "0D018"
"copper (median [IQR])" "<0D001"
"alk.phos (median [IQR])" "0D037"
"ast (mean (SD))" "0D084"
"trig (median [IQR])" "0D017"
"platelet (mean (SD))" "0D067"
"protime (mean (SD))" "0D146"
"stage (%)" "0D246"
" 1" ""
" 2" ""
" 3" ""
" 4" ""
"Stratified by trt"
"" "Overall"
"n" "4,18"
"time (mean (SD))" "19,17D78 (11,04D67)"
"status (%)" ""
" 0" "232 (55D5)"
" 1" "25 (6D0)"
" 2" "161 (38D5)"
"age (mean (SD))" "50D74 (10D45)"
"sex = f (%)" "374 (89D5)"
"ascites = 1 (%)" "24 (7D7)"
"hepato = 1 (%)" "160 (51D3)"
"spiders = 1 (%)" "90 (28D8)"
"edema (%)" ""
" 0" "354 (84D7)"
" 0.5" "44 (10D5)"
" 1" "20 (4D8)"
"bili (median [IQR])" "1D40 [0D80, 3D40]"
"chol (median [IQR])" "3,09D50 [2,49D50, 4,00D00]"
"albumin (mean (SD))" "3D50 (0D42)"
"copper (median [IQR])" "73D00 [41D25, 1,23D00]"
"alk.phos (median [IQR])" "12,59D00 [8,71D50, 19,80D00]"
"ast (mean (SD))" "1,22D56 (56D70)"
"trig (median [IQR])" "1,08D00 [84D25, 1,51D00]"
"platelet (mean (SD))" "2,57D02 (98D33)"
"protime (mean (SD))" "10D73 (1D02)"
"stage (%)" ""
" 1" "21 (5D1)"
" 2" "92 (22D3)"
" 3" "155 (37D6)"
" 4" "144 (35D0)"
"Stratified by trt"
"" "1"
"n" "1,58"
"time (mean (SD))" "20,15D62 (10,94D12)"
"status (%)" ""
" 0" "83 (52D5)"
" 1" "10 (6D3)"
" 2" "65 (41D1)"
"age (mean (SD))" "51D42 (11D01)"
"sex = f (%)" "137 (86D7)"
"ascites = 1 (%)" "14 (8D9)"
"hepato = 1 (%)" "73 (46D2)"
"spiders = 1 (%)" "45 (28D5)"
"edema (%)" ""
" 0" "132 (83D5)"
" 0.5" "16 (10D1)"
" 1" "10 (6D3)"
"bili (median [IQR])" "1D40 [0D80, 3D20]"
"chol (median [IQR])" "3,15D50 [2,47D75, 4,17D00]"
"albumin (mean (SD))" "3D52 (0D44)"
"copper (median [IQR])" "73D00 [40D00, 1,21D00]"
"alk.phos (median [IQR])" "12,14D50 [8,40D75, 20,28D00]"
"ast (mean (SD))" "1,20D21 (54D52)"
"trig (median [IQR])" "1,06D00 [84D50, 1,46D00]"
"platelet (mean (SD))" "2,58D75 (1,00D32)"
"protime (mean (SD))" "10D65 (0D85)"
"stage (%)" ""
" 1" "12 (7D6)"
" 2" "35 (22D2)"
" 3" "56 (35D4)"
" 4" "55 (34D8)"
"Stratified by trt"
"" "2" "p" "test"
"n" "1,54" "" ""
"time (mean (SD))" "19,96D86 (11,55D93)" "0D883" ""
"status (%)" "" "0D884" "exact"
" 0" "85 (55D2)" "" ""
" 1" "9 (5D8)" "" ""
" 2" "60 (39D0)" "" ""
"age (mean (SD))" "48D58 (9D96)" "0D018" ""
"sex = f (%)" "139 (90D3)" "0D421" ""
"ascites = 1 (%)" "10 (6D5)" "0D567" ""
"hepato = 1 (%)" "87 (56D5)" "0D088" ""
"spiders = 1 (%)" "45 (29D2)" "0D985" ""
"edema (%)" "" "0D877" ""
" 0" "131 (85D1)" "" ""
" 0.5" "13 (8D4)" "" ""
" 1" "10 (6D5)" "" ""
"bili (median [IQR])" "1D30 [0D72, 3D60]" "0D842" "nonnorm"
"chol (median [IQR])" "3,03D50 [2,54D25, 3,77D00]" "0D544" "nonnorm"
"albumin (mean (SD))" "3D52 (0D40)" "0D874" ""
"copper (median [IQR])" "73D00 [43D00, 1,39D00]" "0D717" "nonnorm"
"alk.phos (median [IQR])" "12,83D00 [9,22D50, 19,49D75]" "0D812" "nonnorm"
"ast (mean (SD))" "1,24D97 (58D93)" "0D460" ""
"trig (median [IQR])" "1,13D00 [84D50, 1,55D00]" "0D370" "nonnorm"
"platelet (mean (SD))" "2,65D20 (90D73)" "0D555" ""
"protime (mean (SD))" "10D80 (1D14)" "0D197" ""
"stage (%)" "" "0D205" "exact"
" 1" "4 (2D6)" "" ""
" 2" "32 (20D8)" "" ""
" 3" "64 (41D6)" "" ""
" 4" "54 (35D1)" "" ""
"Stratified by trt"
"" "SMD"
"n" ""
"time (mean (SD))" "0D017"
"status (%)" "0D054"
" 0" ""
" 1" ""
" 2" ""
"age (mean (SD))" "0D270"
"sex = f (%)" "0D111"
"ascites = 1 (%)" "0D089"
"hepato = 1 (%)" "0D207"
"spiders = 1 (%)" "0D016"
"edema (%)" "0D058"
" 0" ""
" 0.5" ""
" 1" ""
"bili (median [IQR])" "0D171"
"chol (median [IQR])" "0D038"
"albumin (mean (SD))" "0D018"
"copper (median [IQR])" "<0D001"
"alk.phos (median [IQR])" "0D037"
"ast (mean (SD))" "0D084"
"trig (median [IQR])" "0D017"
"platelet (mean (SD))" "0D067"
"protime (mean (SD))" "0D146"
"stage (%)" "0D246"
" 1" ""
" 2" ""
" 3" ""
" 4" ""
Stratified by trt:sex
Overall 1:m
n 4,18 21
time (mean (SD)) 19,17D78 (11,04D67) 17,93D48 (12,44D70)
status (%)
0 232 (55D5) 4 (19D0)
1 25 ( 6D0) 3 (14D3)
2 161 (38D5) 14 (66D7)
age (mean (SD)) 50D74 (10D45) 55D57 (12D61)
sex = f (%) 374 (89D5) 0 ( 0D0)
ascites = 1 (%) 24 ( 7D7) 1 ( 4D8)
hepato = 1 (%) 160 (51D3) 12 (57D1)
spiders = 1 (%) 90 (28D8) 3 (14D3)
edema (%)
0 354 (84D7) 17 (81D0)
0.5 44 (10D5) 3 (14D3)
1 20 ( 4D8) 1 ( 4D8)
bili (mean (SD)) 3D22 (4D41) 2D98 (2D11)
chol (mean (SD)) 3,69D51 (2,31D94) 4,03D43 (2,04D95)
albumin (mean (SD)) 3D50 (0D42) 3D63 (0D43)
copper (mean (SD)) 97D65 (85D61) 1,74D90 (1,05D33)
alk.phos (mean (SD)) 19,82D66 (21,40D39) 24,86D16 (23,85D32)
ast (mean (SD)) 1,22D56 (56D70) 1,28D71 (48D74)
trig (mean (SD)) 1,24D70 (65D15) 1,45D81 (56D62)
platelet (mean (SD)) 2,57D02 (98D33) 2,32D65 (97D38)
protime (mean (SD)) 10D73 (1D02) 10D84 (0D94)
stage (%)
1 21 ( 5D1) 2 ( 9D5)
2 92 (22D3) 4 (19D0)
3 155 (37D6) 7 (33D3)
4 144 (35D0) 8 (38D1)
Stratified by trt:sex
2:m 1:f
n 15 1,37
time (mean (SD)) 21,56D33 (14,28D56) 20,49D67 (10,70D20)
status (%)
0 7 (46D7) 79 ( 57D7)
1 0 ( 0D0) 7 ( 5D1)
2 8 (53D3) 51 ( 37D2)
age (mean (SD)) 57D09 (10D07) 50D78 (10D65)
sex = f (%) 0 ( 0D0) 137 (1,00D0)
ascites = 1 (%) 2 (13D3) 13 ( 9D5)
hepato = 1 (%) 9 (60D0) 61 ( 44D5)
spiders = 1 (%) 1 ( 6D7) 42 ( 30D7)
edema (%)
0 12 (80D0) 115 ( 83D9)
0.5 1 ( 6D7) 13 ( 9D5)
1 2 (13D3) 9 ( 6D6)
bili (mean (SD)) 2D72 (2D46) 2D86 (3D81)
chol (mean (SD)) 3,01D00 (1,11D32) 3,58D24 (2,10D46)
albumin (mean (SD)) 3D50 (0D49) 3D50 (0D44)
copper (mean (SD)) 1,25D40 (89D18) 85D71 (82D27)
alk.phos (mean (SD)) 17,34D45 (24,78D07) 19,50D04 (21,51D35)
ast (mean (SD)) 1,12D58 (44D38) 1,18D91 (55D40)
trig (mean (SD)) 1,14D86 (39D59) 1,20D28 (73D41)
platelet (mean (SD)) 2,40D13 (73D93) 2,62D59 (1,00D53)
protime (mean (SD)) 11D23 (0D97) 10D62 (0D84)
stage (%)
1 1 ( 6D7) 10 ( 7D3)
2 2 (13D3) 31 ( 22D6)
3 5 (33D3) 49 ( 35D8)
4 7 (46D7) 47 ( 34D3)
Stratified by trt:sex
2:f p test SMD
n 1,39
time (mean (SD)) 19,79D65 (11,27D52) 0D730 0D156
status (%) 0D033 0D577
0 78 ( 56D1)
1 9 ( 6D5)
2 52 ( 37D4)
age (mean (SD)) 47D66 (9D54) <0D001 0D521
sex = f (%) 139 (1,00D0) <0D001 NaN
ascites = 1 (%) 8 ( 5D8) 0D516 0D176
hepato = 1 (%) 78 ( 56D1) 0D208 0D160
spiders = 1 (%) 44 ( 31D7) 0D089 0D402
edema (%) 0D906 0D212
0 119 ( 85D6)
0.5 12 ( 8D6)
1 8 ( 5D8)
bili (mean (SD)) 3D75 (5D50) 0D394 0D135
chol (mean (SD)) 3,81D73 (2,62D26) 0D512 0D295
albumin (mean (SD)) 3D53 (0D39) 0D585 0D164
copper (mean (SD)) 94D64 (79D25) <0D001 0D542
alk.phos (mean (SD)) 19,65D52 (20,66D15) 0D706 0D163
ast (mean (SD)) 1,26D30 (60D27) 0D598 0D182
trig (mean (SD)) 1,26D38 (60D22) 0D370 0D294
platelet (mean (SD)) 2,67D95 (92D20) 0D362 0D234
protime (mean (SD)) 10D75 (1D15) 0D137 0D328
stage (%) 0D646 0D277
1 3 ( 2D2)
2 30 ( 21D6)
3 59 ( 42D4)
4 47 ( 33D8)
Stratified by trt:sex
Overall 1:m
n 4,18 21
time (mean (SD)) 19,17D78 (11,04D67) 17,93D48 (12,44D70)
status (%)
0 232 (55D5) 4 (19D0)
1 25 ( 6D0) 3 (14D3)
2 161 (38D5) 14 (66D7)
age (mean (SD)) 50D74 (10D45) 55D57 (12D61)
sex = f (%) 374 (89D5) 0 ( 0D0)
ascites = 1 (%) 24 ( 7D7) 1 ( 4D8)
hepato = 1 (%) 160 (51D3) 12 (57D1)
spiders = 1 (%) 90 (28D8) 3 (14D3)
edema (%)
0 354 (84D7) 17 (81D0)
0.5 44 (10D5) 3 (14D3)
1 20 ( 4D8) 1 ( 4D8)
bili (mean (SD)) 3D22 (4D41) 2D98 (2D11)
chol (mean (SD)) 3,69D51 (2,31D94) 4,03D43 (2,04D95)
albumin (mean (SD)) 3D50 (0D42) 3D63 (0D43)
copper (mean (SD)) 97D65 (85D61) 1,74D90 (1,05D33)
alk.phos (mean (SD)) 19,82D66 (21,40D39) 24,86D16 (23,85D32)
ast (mean (SD)) 1,22D56 (56D70) 1,28D71 (48D74)
trig (mean (SD)) 1,24D70 (65D15) 1,45D81 (56D62)
platelet (mean (SD)) 2,57D02 (98D33) 2,32D65 (97D38)
protime (mean (SD)) 10D73 (1D02) 10D84 (0D94)
stage (%)
1 21 ( 5D1) 2 ( 9D5)
2 92 (22D3) 4 (19D0)
3 155 (37D6) 7 (33D3)
4 144 (35D0) 8 (38D1)
Stratified by trt:sex
2:m 1:f
n 15 1,37
time (mean (SD)) 21,56D33 (14,28D56) 20,49D67 (10,70D20)
status (%)
0 7 (46D7) 79 ( 57D7)
1 0 ( 0D0) 7 ( 5D1)
2 8 (53D3) 51 ( 37D2)
age (mean (SD)) 57D09 (10D07) 50D78 (10D65)
sex = f (%) 0 ( 0D0) 137 (1,00D0)
ascites = 1 (%) 2 (13D3) 13 ( 9D5)
hepato = 1 (%) 9 (60D0) 61 ( 44D5)
spiders = 1 (%) 1 ( 6D7) 42 ( 30D7)
edema (%)
0 12 (80D0) 115 ( 83D9)
0.5 1 ( 6D7) 13 ( 9D5)
1 2 (13D3) 9 ( 6D6)
bili (mean (SD)) 2D72 (2D46) 2D86 (3D81)
chol (mean (SD)) 3,01D00 (1,11D32) 3,58D24 (2,10D46)
albumin (mean (SD)) 3D50 (0D49) 3D50 (0D44)
copper (mean (SD)) 1,25D40 (89D18) 85D71 (82D27)
alk.phos (mean (SD)) 17,34D45 (24,78D07) 19,50D04 (21,51D35)
ast (mean (SD)) 1,12D58 (44D38) 1,18D91 (55D40)
trig (mean (SD)) 1,14D86 (39D59) 1,20D28 (73D41)
platelet (mean (SD)) 2,40D13 (73D93) 2,62D59 (1,00D53)
protime (mean (SD)) 11D23 (0D97) 10D62 (0D84)
stage (%)
1 1 ( 6D7) 10 ( 7D3)
2 2 (13D3) 31 ( 22D6)
3 5 (33D3) 49 ( 35D8)
4 7 (46D7) 47 ( 34D3)
Stratified by trt:sex
2:f p test SMD
n 1,39
time (mean (SD)) 19,79D65 (11,27D52) 0D730 0D156
status (%) 0D033 0D577
0 78 ( 56D1)
1 9 ( 6D5)
2 52 ( 37D4)
age (mean (SD)) 47D66 (9D54) <0D001 0D521
sex = f (%) 139 (1,00D0) <0D001 NaN
ascites = 1 (%) 8 ( 5D8) 0D516 0D176
hepato = 1 (%) 78 ( 56D1) 0D208 0D160
spiders = 1 (%) 44 ( 31D7) 0D089 0D402
edema (%) 0D906 0D212
0 119 ( 85D6)
0.5 12 ( 8D6)
1 8 ( 5D8)
bili (mean (SD)) 3D75 (5D50) 0D394 0D135
chol (mean (SD)) 3,81D73 (2,62D26) 0D512 0D295
albumin (mean (SD)) 3D53 (0D39) 0D585 0D164
copper (mean (SD)) 94D64 (79D25) <0D001 0D542
alk.phos (mean (SD)) 19,65D52 (20,66D15) 0D706 0D163
ast (mean (SD)) 1,26D30 (60D27) 0D598 0D182
trig (mean (SD)) 1,26D38 (60D22) 0D370 0D294
platelet (mean (SD)) 2,67D95 (92D20) 0D362 0D234
protime (mean (SD)) 10D75 (1D15) 0D137 0D328
stage (%) 0D646 0D277
1 3 ( 2D2)
2 30 ( 21D6)
3 59 ( 42D4)
4 47 ( 33D8)
Stratified by trt:sex
Overall 1:m
n 4,18 21
time (mean (SD)) 19,17D78 (11,04D67) 17,93D48 (12,44D70)
age (mean (SD)) 50D74 (10D45) 55D57 (12D61)
protime (mean (SD)) 10D73 (1D02) 10D84 (0D94)
Stratified by trt:sex
2:m 1:f
n 15 1,37
time (mean (SD)) 21,56D33 (14,28D56) 20,49D67 (10,70D20)
age (mean (SD)) 57D09 (10D07) 50D78 (10D65)
protime (mean (SD)) 11D23 (0D97) 10D62 (0D84)
Stratified by trt:sex
2:f p test SMD
n 1,39
time (mean (SD)) 19,79D65 (11,27D52) 0D730 0D156
age (mean (SD)) 47D66 (9D54) <0D001 0D521
protime (mean (SD)) 10D75 (1D15) 0D137 0D328
Stratified by trt:sex
Overall 1:m
n 4,18 21
time (mean (SD)) 19,17D78 (11,04D67) 17,93D48 (12,44D70)
age (mean (SD)) 50D74 (10D45) 55D57 (12D61)
protime (mean (SD)) 10D73 (1D02) 10D84 (0D94)
Stratified by trt:sex
2:m 1:f
n 15 1,37
time (mean (SD)) 21,56D33 (14,28D56) 20,49D67 (10,70D20)
age (mean (SD)) 57D09 (10D07) 50D78 (10D65)
protime (mean (SD)) 11D23 (0D97) 10D62 (0D84)
Stratified by trt:sex
2:f p test SMD
n 1,39
time (mean (SD)) 19,79D65 (11,27D52) 0D730 0D156
age (mean (SD)) 47D66 (9D54) <0D001 0D521
protime (mean (SD)) 10D75 (1D15) 0D137 0D328
Stratified by trt:sex
Overall 1:m 2:m 1:f
n 4,18 21 15 1,37
status (%)
0 232 (55D5) 4 (19D0) 7 ( 46D7) 79 ( 57D7)
1 25 ( 6D0) 3 (14D3) 0 ( 0D0) 7 ( 5D1)
2 161 (38D5) 14 (66D7) 8 ( 53D3) 51 ( 37D2)
trt = 2 (%) 154 (49D4) 0 ( 0D0) 15 (1,00D0) 0 ( 0D0)
sex = f (%) 374 (89D5) 0 ( 0D0) 0 ( 0D0) 137 (1,00D0)
Stratified by trt:sex
2:f p test SMD
n 1,39
status (%) 0D033 0D577
0 78 ( 56D1)
1 9 ( 6D5)
2 52 ( 37D4)
trt = 2 (%) 139 (1,00D0) <0D001 NaN
sex = f (%) 139 (1,00D0) <0D001 NaN
Stratified by trt:sex
Overall 1:m 2:m 1:f
n 4,18 21 15 1,37
status (%)
0 232 (55D5) 4 (19D0) 7 ( 46D7) 79 ( 57D7)
1 25 ( 6D0) 3 (14D3) 0 ( 0D0) 7 ( 5D1)
2 161 (38D5) 14 (66D7) 8 ( 53D3) 51 ( 37D2)
trt = 2 (%) 154 (49D4) 0 ( 0D0) 15 (1,00D0) 0 ( 0D0)
sex = f (%) 374 (89D5) 0 ( 0D0) 0 ( 0D0) 137 (1,00D0)
Stratified by trt:sex
2:f p test SMD
n 1,39
status (%) 0D033 0D577
0 78 ( 56D1)
1 9 ( 6D5)
2 52 ( 37D4)
trt = 2 (%) 139 (1,00D0) <0D001 NaN
sex = f (%) 139 (1,00D0) <0D001 NaN
Stratified by trt
1 2 p test
n 158 154
status (%) 0.894
0 83 (52.5) 85 (55.2)
1 10 ( 6.3) 9 ( 5.8)
2 65 (41.1) 60 (39.0)
sex = f (%) 137 (86.7) 139 (90.3) 0.421
ascites = 1 (%) 14 ( 8.9) 10 ( 6.5) 0.567
hepato = 1 (%) 73 (46.2) 87 (56.5) 0.088
spiders = 1 (%) 45 (28.5) 45 (29.2) 0.985
edema (%) 0.877
0 132 (83.5) 131 (85.1)
0.5 16 (10.1) 13 ( 8.4)
1 10 ( 6.3) 10 ( 6.5)
stage (%) 0.201
1 12 ( 7.6) 4 ( 2.6)
2 35 (22.2) 32 (20.8)
3 56 (35.4) 64 (41.6)
4 55 (34.8) 54 (35.1)
Stratified by trt
1 2 p test
n 158 154
status (%) 0.894
0 83 (52.5) 85 (55.2)
1 10 ( 6.3) 9 ( 5.8)
2 65 (41.1) 60 (39.0)
sex = f (%) 137 (86.7) 139 (90.3) 0.421
ascites = 1 (%) 14 ( 8.9) 10 ( 6.5) 0.567
hepato = 1 (%) 73 (46.2) 87 (56.5) 0.088
spiders = 1 (%) 45 (28.5) 45 (29.2) 0.985
edema (%) 0.877
0 132 (83.5) 131 (85.1)
0.5 16 (10.1) 13 ( 8.4)
1 10 ( 6.3) 10 ( 6.5)
stage (%) 0.201
1 12 ( 7.6) 4 ( 2.6)
2 35 (22.2) 32 (20.8)
3 56 (35.4) 64 (41.6)
4 55 (34.8) 54 (35.1)
Overall
n 418
status (%)
0 232 (55.5)
1 25 ( 6.0)
2 161 (38.5)
sex = f (%) 374 (89.5)
ascites = 1 (%) 24 ( 7.7)
hepato = 1 (%) 160 (51.3)
spiders = 1 (%) 90 (28.8)
edema (%)
0 354 (84.7)
0.5 44 (10.5)
1 20 ( 4.8)
stage (%)
1 21 ( 5.1)
2 92 (22.3)
3 155 (37.6)
4 144 (35.0)
Overall
n 418
status (%)
0 232 (55.5)
1 25 ( 6.0)
2 161 (38.5)
sex = f (%) 374 (89.5)
ascites = 1 (%) 24 ( 7.7)
hepato = 1 (%) 160 (51.3)
spiders = 1 (%) 90 (28.8)
edema (%)
0 354 (84.7)
0.5 44 (10.5)
1 20 ( 4.8)
stage (%)
1 21 ( 5.1)
2 92 (22.3)
3 155 (37.6)
4 144 (35.0)
Overall
n 418
status (%)
0 232 (55.5)
1 25 ( 6.0)
2 161 (38.5)
sex = f (%) 374 (89.5)
ascites (%)
0 288 (68.9)
1 24 ( 5.7)
NA 106 (25.4)
hepato (%)
0 152 (36.4)
1 160 (38.3)
NA 106 (25.4)
spiders (%)
0 222 (53.1)
1 90 (21.5)
NA 106 (25.4)
edema (%)
0 354 (84.7)
0.5 44 (10.5)
1 20 ( 4.8)
stage (%)
1 21 ( 5.0)
2 92 (22.0)
3 155 (37.1)
4 144 (34.4)
NA 6 ( 1.4)
Overall
n 418
status (%)
0 232 (55.5)
1 25 ( 6.0)
2 161 (38.5)
sex = f (%) 374 (89.5)
ascites (%)
0 288 (68.9)
1 24 ( 5.7)
NA 106 (25.4)
hepato (%)
0 152 (36.4)
1 160 (38.3)
NA 106 (25.4)
spiders (%)
0 222 (53.1)
1 90 (21.5)
NA 106 (25.4)
edema (%)
0 354 (84.7)
0.5 44 (10.5)
1 20 ( 4.8)
stage (%)
1 21 ( 5.0)
2 92 (22.0)
3 155 (37.1)
4 144 (34.4)
NA 6 ( 1.4)
Stratified by trt:sex
1:m 2:m 1:f 2:f p test
n 21 15 137 139
status (%) 0.033
0 4 (19.0) 7 (46.7) 79 ( 57.7) 78 ( 56.1)
1 3 (14.3) 0 ( 0.0) 7 ( 5.1) 9 ( 6.5)
2 14 (66.7) 8 (53.3) 51 ( 37.2) 52 ( 37.4)
sex = f (%) 0 ( 0.0) 0 ( 0.0) 137 (100.0) 139 (100.0) <0.001
ascites = 1 (%) 1 ( 4.8) 2 (13.3) 13 ( 9.5) 8 ( 5.8) 0.516
hepato = 1 (%) 12 (57.1) 9 (60.0) 61 ( 44.5) 78 ( 56.1) 0.208
spiders = 1 (%) 3 (14.3) 1 ( 6.7) 42 ( 30.7) 44 ( 31.7) 0.089
edema (%) 0.906
0 17 (81.0) 12 (80.0) 115 ( 83.9) 119 ( 85.6)
0.5 3 (14.3) 1 ( 6.7) 13 ( 9.5) 12 ( 8.6)
1 1 ( 4.8) 2 (13.3) 9 ( 6.6) 8 ( 5.8)
stage (%) 0.646
1 2 ( 9.5) 1 ( 6.7) 10 ( 7.3) 3 ( 2.2)
2 4 (19.0) 2 (13.3) 31 ( 22.6) 30 ( 21.6)
3 7 (33.3) 5 (33.3) 49 ( 35.8) 59 ( 42.4)
4 8 (38.1) 7 (46.7) 47 ( 34.3) 47 ( 33.8)
Stratified by trt:sex
1:m 2:m 1:f 2:f p test
n 21 15 137 139
status (%) 0.033
0 4 (19.0) 7 (46.7) 79 ( 57.7) 78 ( 56.1)
1 3 (14.3) 0 ( 0.0) 7 ( 5.1) 9 ( 6.5)
2 14 (66.7) 8 (53.3) 51 ( 37.2) 52 ( 37.4)
sex = f (%) 0 ( 0.0) 0 ( 0.0) 137 (100.0) 139 (100.0) <0.001
ascites = 1 (%) 1 ( 4.8) 2 (13.3) 13 ( 9.5) 8 ( 5.8) 0.516
hepato = 1 (%) 12 (57.1) 9 (60.0) 61 ( 44.5) 78 ( 56.1) 0.208
spiders = 1 (%) 3 (14.3) 1 ( 6.7) 42 ( 30.7) 44 ( 31.7) 0.089
edema (%) 0.906
0 17 (81.0) 12 (80.0) 115 ( 83.9) 119 ( 85.6)
0.5 3 (14.3) 1 ( 6.7) 13 ( 9.5) 12 ( 8.6)
1 1 ( 4.8) 2 (13.3) 9 ( 6.6) 8 ( 5.8)
stage (%) 0.646
1 2 ( 9.5) 1 ( 6.7) 10 ( 7.3) 3 ( 2.2)
2 4 (19.0) 2 (13.3) 31 ( 22.6) 30 ( 21.6)
3 7 (33.3) 5 (33.3) 49 ( 35.8) 59 ( 42.4)
4 8 (38.1) 7 (46.7) 47 ( 34.3) 47 ( 33.8)
Stratified by trt:sex
1:m 2:m 1:f 2:f
n 21 15 137 139
status (%)
0 4 (19.048) 7 (46.667) 79 ( 57.664) 78 ( 56.115)
1 3 (14.286) 0 ( 0.000) 7 ( 5.109) 9 ( 6.475)
2 14 (66.667) 8 (53.333) 51 ( 37.226) 52 ( 37.410)
sex = f (%) 0 ( 0.000) 0 ( 0.000) 137 (100.000) 139 (100.000)
ascites = 1 (%) 1 ( 4.762) 2 (13.333) 13 ( 9.489) 8 ( 5.755)
hepato = 1 (%) 12 (57.143) 9 (60.000) 61 ( 44.526) 78 ( 56.115)
spiders = 1 (%) 3 (14.286) 1 ( 6.667) 42 ( 30.657) 44 ( 31.655)
edema (%)
0 17 (80.952) 12 (80.000) 115 ( 83.942) 119 ( 85.612)
0.5 3 (14.286) 1 ( 6.667) 13 ( 9.489) 12 ( 8.633)
1 1 ( 4.762) 2 (13.333) 9 ( 6.569) 8 ( 5.755)
stage (%)
1 2 ( 9.524) 1 ( 6.667) 10 ( 7.299) 3 ( 2.158)
2 4 (19.048) 2 (13.333) 31 ( 22.628) 30 ( 21.583)
3 7 (33.333) 5 (33.333) 49 ( 35.766) 59 ( 42.446)
4 8 (38.095) 7 (46.667) 47 ( 34.307) 47 ( 33.813)
Stratified by trt:sex
p test
n
status (%) 0.03270
0
1
2
sex = f (%) <0.00001
ascites = 1 (%) 0.51569
hepato = 1 (%) 0.20806
spiders = 1 (%) 0.08899
edema (%) 0.90584
0
0.5
1
stage (%) 0.64630
1
2
3
4
Stratified by trt:sex
1:m 2:m 1:f 2:f
n 21 15 137 139
status (%)
0 4 (19.048) 7 (46.667) 79 ( 57.664) 78 ( 56.115)
1 3 (14.286) 0 ( 0.000) 7 ( 5.109) 9 ( 6.475)
2 14 (66.667) 8 (53.333) 51 ( 37.226) 52 ( 37.410)
sex = f (%) 0 ( 0.000) 0 ( 0.000) 137 (100.000) 139 (100.000)
ascites = 1 (%) 1 ( 4.762) 2 (13.333) 13 ( 9.489) 8 ( 5.755)
hepato = 1 (%) 12 (57.143) 9 (60.000) 61 ( 44.526) 78 ( 56.115)
spiders = 1 (%) 3 (14.286) 1 ( 6.667) 42 ( 30.657) 44 ( 31.655)
edema (%)
0 17 (80.952) 12 (80.000) 115 ( 83.942) 119 ( 85.612)
0.5 3 (14.286) 1 ( 6.667) 13 ( 9.489) 12 ( 8.633)
1 1 ( 4.762) 2 (13.333) 9 ( 6.569) 8 ( 5.755)
stage (%)
1 2 ( 9.524) 1 ( 6.667) 10 ( 7.299) 3 ( 2.158)
2 4 (19.048) 2 (13.333) 31 ( 22.628) 30 ( 21.583)
3 7 (33.333) 5 (33.333) 49 ( 35.766) 59 ( 42.446)
4 8 (38.095) 7 (46.667) 47 ( 34.307) 47 ( 33.813)
Stratified by trt:sex
p test
n
status (%) 0.03270
0
1
2
sex = f (%) <0.00001
ascites = 1 (%) 0.51569
hepato = 1 (%) 0.20806
spiders = 1 (%) 0.08899
edema (%) 0.90584
0
0.5
1
stage (%) 0.64630
1
2
3
4
Stratified by trt:sex
1:m 2:m 1:f 2:f
n 21 15 137 139
status (%)
0 4 (19.0) 7 (46.7) 79 ( 57.7) 78 ( 56.1)
1 3 (14.3) 0 ( 0.0) 7 ( 5.1) 9 ( 6.5)
2 14 (66.7) 8 (53.3) 51 ( 37.2) 52 ( 37.4)
sex = f (%) 0 ( 0.0) 0 ( 0.0) 137 (100.0) 139 (100.0)
ascites = 1 (%) 1 ( 4.8) 2 (13.3) 13 ( 9.5) 8 ( 5.8)
hepato = 1 (%) 12 (57.1) 9 (60.0) 61 ( 44.5) 78 ( 56.1)
spiders = 1 (%) 3 (14.3) 1 ( 6.7) 42 ( 30.7) 44 ( 31.7)
edema (%)
0 17 (81.0) 12 (80.0) 115 ( 83.9) 119 ( 85.6)
0.5 3 (14.3) 1 ( 6.7) 13 ( 9.5) 12 ( 8.6)
1 1 ( 4.8) 2 (13.3) 9 ( 6.6) 8 ( 5.8)
stage (%)
1 2 ( 9.5) 1 ( 6.7) 10 ( 7.3) 3 ( 2.2)
2 4 (19.0) 2 (13.3) 31 ( 22.6) 30 ( 21.6)
3 7 (33.3) 5 (33.3) 49 ( 35.8) 59 ( 42.4)
4 8 (38.1) 7 (46.7) 47 ( 34.3) 47 ( 33.8)
Stratified by trt:sex
1:m 2:m 1:f 2:f
n 21 15 137 139
status (%)
0 4 (19.0) 7 (46.7) 79 ( 57.7) 78 ( 56.1)
1 3 (14.3) 0 ( 0.0) 7 ( 5.1) 9 ( 6.5)
2 14 (66.7) 8 (53.3) 51 ( 37.2) 52 ( 37.4)
sex = f (%) 0 ( 0.0) 0 ( 0.0) 137 (100.0) 139 (100.0)
ascites = 1 (%) 1 ( 4.8) 2 (13.3) 13 ( 9.5) 8 ( 5.8)
hepato = 1 (%) 12 (57.1) 9 (60.0) 61 ( 44.5) 78 ( 56.1)
spiders = 1 (%) 3 (14.3) 1 ( 6.7) 42 ( 30.7) 44 ( 31.7)
edema (%)
0 17 (81.0) 12 (80.0) 115 ( 83.9) 119 ( 85.6)
0.5 3 (14.3) 1 ( 6.7) 13 ( 9.5) 12 ( 8.6)
1 1 ( 4.8) 2 (13.3) 9 ( 6.6) 8 ( 5.8)
stage (%)
1 2 ( 9.5) 1 ( 6.7) 10 ( 7.3) 3 ( 2.2)
2 4 (19.0) 2 (13.3) 31 ( 22.6) 30 ( 21.6)
3 7 (33.3) 5 (33.3) 49 ( 35.8) 59 ( 42.4)
4 8 (38.1) 7 (46.7) 47 ( 34.3) 47 ( 33.8)
Stratified by trt
1 2 p test
n 158 154
status (%) 0.894
0 83 (52.5) 85 (55.2)
1 10 (6.3) 9 (5.8)
2 65 (41.1) 60 (39.0)
sex = f (%) 137 (86.7) 139 (90.3) 0.421
ascites = 1 (%) 14 (8.9) 10 (6.5) 0.567
hepato = 1 (%) 73 (46.2) 87 (56.5) 0.088
spiders = 1 (%) 45 (28.5) 45 (29.2) 0.985
edema (%) 0.877
0 132 (83.5) 131 (85.1)
0.5 16 (10.1) 13 (8.4)
1 10 (6.3) 10 (6.5)
stage (%) 0.201
1 12 (7.6) 4 (2.6)
2 35 (22.2) 32 (20.8)
3 56 (35.4) 64 (41.6)
4 55 (34.8) 54 (35.1)
Stratified by trt
1 2 p test
n 158 154
status (%) 0.894
0 83 (52.5) 85 (55.2)
1 10 (6.3) 9 (5.8)
2 65 (41.1) 60 (39.0)
sex = f (%) 137 (86.7) 139 (90.3) 0.421
ascites = 1 (%) 14 (8.9) 10 (6.5) 0.567
hepato = 1 (%) 73 (46.2) 87 (56.5) 0.088
spiders = 1 (%) 45 (28.5) 45 (29.2) 0.985
edema (%) 0.877
0 132 (83.5) 131 (85.1)
0.5 16 (10.1) 13 (8.4)
1 10 (6.3) 10 (6.5)
stage (%) 0.201
1 12 (7.6) 4 (2.6)
2 35 (22.2) 32 (20.8)
3 56 (35.4) 64 (41.6)
4 55 (34.8) 54 (35.1)
Stratified by trt
level 1 2 p test
n 158 154
status (%) 0 83 (52.5) 85 (55.2) 0.894
1 10 ( 6.3) 9 ( 5.8)
2 65 (41.1) 60 (39.0)
sex (%) m 21 (13.3) 15 ( 9.7) 0.421
f 137 (86.7) 139 (90.3)
ascites (%) 0 144 (91.1) 144 (93.5) 0.567
1 14 ( 8.9) 10 ( 6.5)
hepato (%) 0 85 (53.8) 67 (43.5) 0.088
1 73 (46.2) 87 (56.5)
spiders (%) 0 113 (71.5) 109 (70.8) 0.985
1 45 (28.5) 45 (29.2)
edema (%) 0 132 (83.5) 131 (85.1) 0.877
0.5 16 (10.1) 13 ( 8.4)
1 10 ( 6.3) 10 ( 6.5)
stage (%) 1 12 ( 7.6) 4 ( 2.6) 0.201
2 35 (22.2) 32 (20.8)
3 56 (35.4) 64 (41.6)
4 55 (34.8) 54 (35.1)
Stratified by trt
level 1 2 p test
n 158 154
status (%) 0 83 (52.5) 85 (55.2) 0.894
1 10 ( 6.3) 9 ( 5.8)
2 65 (41.1) 60 (39.0)
sex (%) m 21 (13.3) 15 ( 9.7) 0.421
f 137 (86.7) 139 (90.3)
ascites (%) 0 144 (91.1) 144 (93.5) 0.567
1 14 ( 8.9) 10 ( 6.5)
hepato (%) 0 85 (53.8) 67 (43.5) 0.088
1 73 (46.2) 87 (56.5)
spiders (%) 0 113 (71.5) 109 (70.8) 0.985
1 45 (28.5) 45 (29.2)
edema (%) 0 132 (83.5) 131 (85.1) 0.877
0.5 16 (10.1) 13 ( 8.4)
1 10 ( 6.3) 10 ( 6.5)
stage (%) 1 12 ( 7.6) 4 ( 2.6) 0.201
2 35 (22.2) 32 (20.8)
3 56 (35.4) 64 (41.6)
4 55 (34.8) 54 (35.1)
Stratified by trt
1 2 p test
n 158 154
status 0.894
0 83 (52.5) 85 (55.2)
1 10 ( 6.3) 9 ( 5.8)
2 65 (41.1) 60 (39.0)
sex = f 137 (86.7) 139 (90.3) 0.421
ascites = 1 14 ( 8.9) 10 ( 6.5) 0.567
hepato = 1 73 (46.2) 87 (56.5) 0.088
spiders = 1 45 (28.5) 45 (29.2) 0.985
edema 0.877
0 132 (83.5) 131 (85.1)
0.5 16 (10.1) 13 ( 8.4)
1 10 ( 6.3) 10 ( 6.5)
stage 0.201
1 12 ( 7.6) 4 ( 2.6)
2 35 (22.2) 32 (20.8)
3 56 (35.4) 64 (41.6)
4 55 (34.8) 54 (35.1)
Stratified by trt
1 2 p test
n 158 154
status 0.894
0 83 (52.5) 85 (55.2)
1 10 ( 6.3) 9 ( 5.8)
2 65 (41.1) 60 (39.0)
sex = f 137 (86.7) 139 (90.3) 0.421
ascites = 1 14 ( 8.9) 10 ( 6.5) 0.567
hepato = 1 73 (46.2) 87 (56.5) 0.088
spiders = 1 45 (28.5) 45 (29.2) 0.985
edema 0.877
0 132 (83.5) 131 (85.1)
0.5 16 (10.1) 13 ( 8.4)
1 10 ( 6.3) 10 ( 6.5)
stage 0.201
1 12 ( 7.6) 4 ( 2.6)
2 35 (22.2) 32 (20.8)
3 56 (35.4) 64 (41.6)
4 55 (34.8) 54 (35.1)
Stratified by trt
1 2 p test
n 158 154
status 0.894
0 83 85
1 10 9
2 65 60
sex = f 137 139 0.421
ascites = 1 14 10 0.567
hepato = 1 73 87 0.088
spiders = 1 45 45 0.985
edema 0.877
0 132 131
0.5 16 13
1 10 10
stage 0.201
1 12 4
2 35 32
3 56 64
4 55 54
Stratified by trt
1 2 p test
n 158 154
status 0.894
0 83 85
1 10 9
2 65 60
sex = f 137 139 0.421
ascites = 1 14 10 0.567
hepato = 1 73 87 0.088
spiders = 1 45 45 0.985
edema 0.877
0 132 131
0.5 16 13
1 10 10
stage 0.201
1 12 4
2 35 32
3 56 64
4 55 54
Stratified by trt
1 2 p test
n 158 154
status (%) 0.894
0 52.5 55.2
1 6.3 5.8
2 41.1 39.0
sex = f (%) 86.7 90.3 0.421
ascites = 1 (%) 8.9 6.5 0.567
hepato = 1 (%) 46.2 56.5 0.088
spiders = 1 (%) 28.5 29.2 0.985
edema (%) 0.877
0 83.5 85.1
0.5 10.1 8.4
1 6.3 6.5
stage (%) 0.201
1 7.6 2.6
2 22.2 20.8
3 35.4 41.6
4 34.8 35.1
Stratified by trt
1 2 p test
n 158 154
status (%) 0.894
0 52.5 55.2
1 6.3 5.8
2 41.1 39.0
sex = f (%) 86.7 90.3 0.421
ascites = 1 (%) 8.9 6.5 0.567
hepato = 1 (%) 46.2 56.5 0.088
spiders = 1 (%) 28.5 29.2 0.985
edema (%) 0.877
0 83.5 85.1
0.5 10.1 8.4
1 6.3 6.5
stage (%) 0.201
1 7.6 2.6
2 22.2 20.8
3 35.4 41.6
4 34.8 35.1
Stratified by trt
1 2 p test
n 158 154
status % (freq) 0.894
0 52.5 ( 83) 55.2 ( 85)
1 6.3 ( 10) 5.8 ( 9)
2 41.1 ( 65) 39.0 ( 60)
sex = f % (freq) 86.7 (137) 90.3 (139) 0.421
ascites = 1 % (freq) 8.9 ( 14) 6.5 ( 10) 0.567
hepato = 1 % (freq) 46.2 ( 73) 56.5 ( 87) 0.088
spiders = 1 % (freq) 28.5 ( 45) 29.2 ( 45) 0.985
edema % (freq) 0.877
0 83.5 (132) 85.1 (131)
0.5 10.1 ( 16) 8.4 ( 13)
1 6.3 ( 10) 6.5 ( 10)
stage % (freq) 0.201
1 7.6 ( 12) 2.6 ( 4)
2 22.2 ( 35) 20.8 ( 32)
3 35.4 ( 56) 41.6 ( 64)
4 34.8 ( 55) 35.1 ( 54)
Stratified by trt
1 2 p test
n 158 154
status % (freq) 0.894
0 52.5 ( 83) 55.2 ( 85)
1 6.3 ( 10) 5.8 ( 9)
2 41.1 ( 65) 39.0 ( 60)
sex = f % (freq) 86.7 (137) 90.3 (139) 0.421
ascites = 1 % (freq) 8.9 ( 14) 6.5 ( 10) 0.567
hepato = 1 % (freq) 46.2 ( 73) 56.5 ( 87) 0.088
spiders = 1 % (freq) 28.5 ( 45) 29.2 ( 45) 0.985
edema % (freq) 0.877
0 83.5 (132) 85.1 (131)
0.5 10.1 ( 16) 8.4 ( 13)
1 6.3 ( 10) 6.5 ( 10)
stage % (freq) 0.201
1 7.6 ( 12) 2.6 ( 4)
2 22.2 ( 35) 20.8 ( 32)
3 35.4 ( 56) 41.6 ( 64)
4 34.8 ( 55) 35.1 ( 54)
Stratified by trt
1 2 p test
n 158 154
status (%) 0.894
0 83 (52.5) 85 (55.2)
1 10 ( 6.3) 9 ( 5.8)
2 65 (41.1) 60 (39.0)
sex = m/f (%) 21/137 (13.3/86.7) 15/139 (9.7/90.3) 0.421
ascites = 1 (%) 14 ( 8.9) 10 ( 6.5) 0.567
hepato = 1 (%) 73 (46.2) 87 (56.5) 0.088
spiders = 1 (%) 45 (28.5) 45 (29.2) 0.985
edema (%) 0.877
0 132 (83.5) 131 (85.1)
0.5 16 (10.1) 13 ( 8.4)
1 10 ( 6.3) 10 ( 6.5)
stage (%) 0.201
1 12 ( 7.6) 4 ( 2.6)
2 35 (22.2) 32 (20.8)
3 56 (35.4) 64 (41.6)
4 55 (34.8) 54 (35.1)
Stratified by trt
1 2 p test
n 158 154
status (%) 0.894
0 83 (52.5) 85 (55.2)
1 10 ( 6.3) 9 ( 5.8)
2 65 (41.1) 60 (39.0)
sex = m/f (%) 21/137 (13.3/86.7) 15/139 (9.7/90.3) 0.421
ascites = 1 (%) 14 ( 8.9) 10 ( 6.5) 0.567
hepato = 1 (%) 73 (46.2) 87 (56.5) 0.088
spiders = 1 (%) 45 (28.5) 45 (29.2) 0.985
edema (%) 0.877
0 132 (83.5) 131 (85.1)
0.5 16 (10.1) 13 ( 8.4)
1 10 ( 6.3) 10 ( 6.5)
stage (%) 0.201
1 12 ( 7.6) 4 ( 2.6)
2 35 (22.2) 32 (20.8)
3 56 (35.4) 64 (41.6)
4 55 (34.8) 54 (35.1)
"Stratified by trt"
"" "level" "1" "2" "p" "test"
"n" "" "158" "154" "" ""
"status (%)" "0" "83 (52.5)" "85 (55.2)" "0.894" ""
"" "1" "10 (6.3)" "9 (5.8)" "" ""
"" "2" "65 (41.1)" "60 (39.0)" "" ""
"sex (%)" "m" "21 (13.3)" "15 (9.7)" "0.421" ""
"" "f" "137 (86.7)" "139 (90.3)" "" ""
"ascites (%)" "0" "144 (91.1)" "144 (93.5)" "0.567" ""
"" "1" "14 (8.9)" "10 (6.5)" "" ""
"hepato (%)" "0" "85 (53.8)" "67 (43.5)" "0.088" ""
"" "1" "73 (46.2)" "87 (56.5)" "" ""
"spiders (%)" "0" "113 (71.5)" "109 (70.8)" "0.985" ""
"" "1" "45 (28.5)" "45 (29.2)" "" ""
"edema (%)" "0" "132 (83.5)" "131 (85.1)" "0.877" ""
"" "0.5" "16 (10.1)" "13 (8.4)" "" ""
"" "1" "10 (6.3)" "10 (6.5)" "" ""
"stage (%)" "1" "12 (7.6)" "4 (2.6)" "0.201" ""
"" "2" "35 (22.2)" "32 (20.8)" "" ""
"" "3" "56 (35.4)" "64 (41.6)" "" ""
"" "4" "55 (34.8)" "54 (35.1)" "" ""
"Stratified by trt"
"" "level" "1" "2" "p" "test"
"n" "" "158" "154" "" ""
"status (%)" "0" "83 (52.5)" "85 (55.2)" "0.894" ""
"" "1" "10 (6.3)" "9 (5.8)" "" ""
"" "2" "65 (41.1)" "60 (39.0)" "" ""
"sex (%)" "m" "21 (13.3)" "15 (9.7)" "0.421" ""
"" "f" "137 (86.7)" "139 (90.3)" "" ""
"ascites (%)" "0" "144 (91.1)" "144 (93.5)" "0.567" ""
"" "1" "14 (8.9)" "10 (6.5)" "" ""
"hepato (%)" "0" "85 (53.8)" "67 (43.5)" "0.088" ""
"" "1" "73 (46.2)" "87 (56.5)" "" ""
"spiders (%)" "0" "113 (71.5)" "109 (70.8)" "0.985" ""
"" "1" "45 (28.5)" "45 (29.2)" "" ""
"edema (%)" "0" "132 (83.5)" "131 (85.1)" "0.877" ""
"" "0.5" "16 (10.1)" "13 (8.4)" "" ""
"" "1" "10 (6.3)" "10 (6.5)" "" ""
"stage (%)" "1" "12 (7.6)" "4 (2.6)" "0.201" ""
"" "2" "35 (22.2)" "32 (20.8)" "" ""
"" "3" "56 (35.4)" "64 (41.6)" "" ""
"" "4" "55 (34.8)" "54 (35.1)" "" ""
"Stratified by trt"
"" "level" "Overall" "1" "2" "p" "test"
"n" "" "418" "158" "154" "" ""
"status (%)" "0" "232 (55.5)" "83 (52.5)" "85 (55.2)" "0.894" ""
"" "1" "25 (6.0)" "10 (6.3)" "9 (5.8)" "" ""
"" "2" "161 (38.5)" "65 (41.1)" "60 (39.0)" "" ""
"sex (%)" "m" "44 (10.5)" "21 (13.3)" "15 (9.7)" "0.421" ""
"" "f" "374 (89.5)" "137 (86.7)" "139 (90.3)" "" ""
"ascites (%)" "0" "288 (92.3)" "144 (91.1)" "144 (93.5)" "0.567" ""
"" "1" "24 (7.7)" "14 (8.9)" "10 (6.5)" "" ""
"hepato (%)" "0" "152 (48.7)" "85 (53.8)" "67 (43.5)" "0.088" ""
"" "1" "160 (51.3)" "73 (46.2)" "87 (56.5)" "" ""
"spiders (%)" "0" "222 (71.2)" "113 (71.5)" "109 (70.8)" "0.985" ""
"" "1" "90 (28.8)" "45 (28.5)" "45 (29.2)" "" ""
"edema (%)" "0" "354 (84.7)" "132 (83.5)" "131 (85.1)" "0.877" ""
"" "0.5" "44 (10.5)" "16 (10.1)" "13 (8.4)" "" ""
"" "1" "20 (4.8)" "10 (6.3)" "10 (6.5)" "" ""
"stage (%)" "1" "21 (5.1)" "12 (7.6)" "4 (2.6)" "0.201" ""
"" "2" "92 (22.3)" "35 (22.2)" "32 (20.8)" "" ""
"" "3" "155 (37.6)" "56 (35.4)" "64 (41.6)" "" ""
"" "4" "144 (35.0)" "55 (34.8)" "54 (35.1)" "" ""
"Stratified by trt"
"" "level" "Overall" "1" "2" "p" "test"
"n" "" "418" "158" "154" "" ""
"status (%)" "0" "232 (55.5)" "83 (52.5)" "85 (55.2)" "0.894" ""
"" "1" "25 (6.0)" "10 (6.3)" "9 (5.8)" "" ""
"" "2" "161 (38.5)" "65 (41.1)" "60 (39.0)" "" ""
"sex (%)" "m" "44 (10.5)" "21 (13.3)" "15 (9.7)" "0.421" ""
"" "f" "374 (89.5)" "137 (86.7)" "139 (90.3)" "" ""
"ascites (%)" "0" "288 (92.3)" "144 (91.1)" "144 (93.5)" "0.567" ""
"" "1" "24 (7.7)" "14 (8.9)" "10 (6.5)" "" ""
"hepato (%)" "0" "152 (48.7)" "85 (53.8)" "67 (43.5)" "0.088" ""
"" "1" "160 (51.3)" "73 (46.2)" "87 (56.5)" "" ""
"spiders (%)" "0" "222 (71.2)" "113 (71.5)" "109 (70.8)" "0.985" ""
"" "1" "90 (28.8)" "45 (28.5)" "45 (29.2)" "" ""
"edema (%)" "0" "354 (84.7)" "132 (83.5)" "131 (85.1)" "0.877" ""
"" "0.5" "44 (10.5)" "16 (10.1)" "13 (8.4)" "" ""
"" "1" "20 (4.8)" "10 (6.3)" "10 (6.5)" "" ""
"stage (%)" "1" "21 (5.1)" "12 (7.6)" "4 (2.6)" "0.201" ""
"" "2" "92 (22.3)" "35 (22.2)" "32 (20.8)" "" ""
"" "3" "155 (37.6)" "56 (35.4)" "64 (41.6)" "" ""
"" "4" "144 (35.0)" "55 (34.8)" "54 (35.1)" "" ""
Stratified by trt:sex
Overall 1:m 2:m 1:f 2:f
n 418 21 15 137 139
status (%)
0 232 (55.5) 4 (19.0) 7 (46.7) 79 ( 57.7) 78 ( 56.1)
1 25 ( 6.0) 3 (14.3) 0 ( 0.0) 7 ( 5.1) 9 ( 6.5)
2 161 (38.5) 14 (66.7) 8 (53.3) 51 ( 37.2) 52 ( 37.4)
sex = f (%) 374 (89.5) 0 ( 0.0) 0 ( 0.0) 137 (100.0) 139 (100.0)
ascites = 1 (%) 24 ( 7.7) 1 ( 4.8) 2 (13.3) 13 ( 9.5) 8 ( 5.8)
hepato = 1 (%) 160 (51.3) 12 (57.1) 9 (60.0) 61 ( 44.5) 78 ( 56.1)
spiders = 1 (%) 90 (28.8) 3 (14.3) 1 ( 6.7) 42 ( 30.7) 44 ( 31.7)
edema (%)
0 354 (84.7) 17 (81.0) 12 (80.0) 115 ( 83.9) 119 ( 85.6)
0.5 44 (10.5) 3 (14.3) 1 ( 6.7) 13 ( 9.5) 12 ( 8.6)
1 20 ( 4.8) 1 ( 4.8) 2 (13.3) 9 ( 6.6) 8 ( 5.8)
stage (%)
1 21 ( 5.1) 2 ( 9.5) 1 ( 6.7) 10 ( 7.3) 3 ( 2.2)
2 92 (22.3) 4 (19.0) 2 (13.3) 31 ( 22.6) 30 ( 21.6)
3 155 (37.6) 7 (33.3) 5 (33.3) 49 ( 35.8) 59 ( 42.4)
4 144 (35.0) 8 (38.1) 7 (46.7) 47 ( 34.3) 47 ( 33.8)
Stratified by trt:sex
p test
n
status (%) 0.033
0
1
2
sex = f (%) <0.001
ascites = 1 (%) 0.516
hepato = 1 (%) 0.208
spiders = 1 (%) 0.089
edema (%) 0.906
0
0.5
1
stage (%) 0.646
1
2
3
4
Stratified by trt:sex
Overall 1:m 2:m 1:f 2:f
n 418 21 15 137 139
status (%)
0 232 (55.5) 4 (19.0) 7 (46.7) 79 ( 57.7) 78 ( 56.1)
1 25 ( 6.0) 3 (14.3) 0 ( 0.0) 7 ( 5.1) 9 ( 6.5)
2 161 (38.5) 14 (66.7) 8 (53.3) 51 ( 37.2) 52 ( 37.4)
sex = f (%) 374 (89.5) 0 ( 0.0) 0 ( 0.0) 137 (100.0) 139 (100.0)
ascites = 1 (%) 24 ( 7.7) 1 ( 4.8) 2 (13.3) 13 ( 9.5) 8 ( 5.8)
hepato = 1 (%) 160 (51.3) 12 (57.1) 9 (60.0) 61 ( 44.5) 78 ( 56.1)
spiders = 1 (%) 90 (28.8) 3 (14.3) 1 ( 6.7) 42 ( 30.7) 44 ( 31.7)
edema (%)
0 354 (84.7) 17 (81.0) 12 (80.0) 115 ( 83.9) 119 ( 85.6)
0.5 44 (10.5) 3 (14.3) 1 ( 6.7) 13 ( 9.5) 12 ( 8.6)
1 20 ( 4.8) 1 ( 4.8) 2 (13.3) 9 ( 6.6) 8 ( 5.8)
stage (%)
1 21 ( 5.1) 2 ( 9.5) 1 ( 6.7) 10 ( 7.3) 3 ( 2.2)
2 92 (22.3) 4 (19.0) 2 (13.3) 31 ( 22.6) 30 ( 21.6)
3 155 (37.6) 7 (33.3) 5 (33.3) 49 ( 35.8) 59 ( 42.4)
4 144 (35.0) 8 (38.1) 7 (46.7) 47 ( 34.3) 47 ( 33.8)
Stratified by trt:sex
p test
n
status (%) 0.033
0
1
2
sex = f (%) <0.001
ascites = 1 (%) 0.516
hepato = 1 (%) 0.208
spiders = 1 (%) 0.089
edema (%) 0.906
0
0.5
1
stage (%) 0.646
1
2
3
4
Stratified by trt
1 2 p test
n 158 154
status (%) 0.894
0 83 (52.5) 85 (55.2)
1 10 ( 6.3) 9 ( 5.8)
2 65 (41.1) 60 (39.0)
sex = f (%) 137 (86.7) 139 (90.3) 0.421
ascites = 1 (%) 14 ( 8.9) 10 ( 6.5) 0.567
hepato = 1 (%) 73 (46.2) 87 (56.5) 0.088
spiders = 1 (%) 45 (28.5) 45 (29.2) 0.985
edema (%) 0.877
0 132 (83.5) 131 (85.1)
0.5 16 (10.1) 13 ( 8.4)
1 10 ( 6.3) 10 ( 6.5)
stage (%) 0.201
1 12 ( 7.6) 4 ( 2.6)
2 35 (22.2) 32 (20.8)
3 56 (35.4) 64 (41.6)
4 55 (34.8) 54 (35.1)
Cell Contents
|-------------------------|
| N |
| Chi-square contribution |
| N / Row Total |
| N / Col Total |
| N / Table Total |
|-------------------------|
Total Observations in Table: 312
| trt
status | 1 | 2 | Row Total |
-------------|-----------|-----------|-----------|
0 | 83 | 85 | 168 |
| 0.051 | 0.052 | |
| 0.494 | 0.506 | 0.538 |
| 0.525 | 0.552 | |
| 0.266 | 0.272 | |
-------------|-----------|-----------|-----------|
1 | 10 | 9 | 19 |
| 0.015 | 0.015 | |
| 0.526 | 0.474 | 0.061 |
| 0.063 | 0.058 | |
| 0.032 | 0.029 | |
-------------|-----------|-----------|-----------|
2 | 65 | 60 | 125 |
| 0.046 | 0.047 | |
| 0.520 | 0.480 | 0.401 |
| 0.411 | 0.390 | |
| 0.208 | 0.192 | |
-------------|-----------|-----------|-----------|
Column Total | 158 | 154 | 312 |
| 0.506 | 0.494 | |
-------------|-----------|-----------|-----------|
Cell Contents
|-------------------------|
| N |
| Chi-square contribution |
| N / Row Total |
| N / Col Total |
| N / Table Total |
|-------------------------|
Total Observations in Table: 312
| trt
sex | 1 | 2 | Row Total |
-------------|-----------|-----------|-----------|
m | 21 | 15 | 36 |
| 0.421 | 0.432 | |
| 0.583 | 0.417 | 0.115 |
| 0.133 | 0.097 | |
| 0.067 | 0.048 | |
-------------|-----------|-----------|-----------|
f | 137 | 139 | 276 |
| 0.055 | 0.056 | |
| 0.496 | 0.504 | 0.885 |
| 0.867 | 0.903 | |
| 0.439 | 0.446 | |
-------------|-----------|-----------|-----------|
Column Total | 158 | 154 | 312 |
| 0.506 | 0.494 | |
-------------|-----------|-----------|-----------|
Cell Contents
|-------------------------|
| N |
| Chi-square contribution |
| N / Row Total |
| N / Col Total |
| N / Table Total |
|-------------------------|
Total Observations in Table: 312
| trt
ascites | 1 | 2 | Row Total |
-------------|-----------|-----------|-----------|
0 | 144 | 144 | 288 |
| 0.023 | 0.024 | |
| 0.500 | 0.500 | 0.923 |
| 0.911 | 0.935 | |
| 0.462 | 0.462 | |
-------------|-----------|-----------|-----------|
1 | 14 | 10 | 24 |
| 0.280 | 0.288 | |
| 0.583 | 0.417 | 0.077 |
| 0.089 | 0.065 | |
| 0.045 | 0.032 | |
-------------|-----------|-----------|-----------|
Column Total | 158 | 154 | 312 |
| 0.506 | 0.494 | |
-------------|-----------|-----------|-----------|
Cell Contents
|-------------------------|
| N |
| Chi-square contribution |
| N / Row Total |
| N / Col Total |
| N / Table Total |
|-------------------------|
Total Observations in Table: 312
| trt
hepato | 1 | 2 | Row Total |
-------------|-----------|-----------|-----------|
0 | 85 | 67 | 152 |
| 0.837 | 0.859 | |
| 0.559 | 0.441 | 0.487 |
| 0.538 | 0.435 | |
| 0.272 | 0.215 | |
-------------|-----------|-----------|-----------|
1 | 73 | 87 | 160 |
| 0.795 | 0.816 | |
| 0.456 | 0.544 | 0.513 |
| 0.462 | 0.565 | |
| 0.234 | 0.279 | |
-------------|-----------|-----------|-----------|
Column Total | 158 | 154 | 312 |
| 0.506 | 0.494 | |
-------------|-----------|-----------|-----------|
Cell Contents
|-------------------------|
| N |
| Chi-square contribution |
| N / Row Total |
| N / Col Total |
| N / Table Total |
|-------------------------|
Total Observations in Table: 312
| trt
spiders | 1 | 2 | Row Total |
-------------|-----------|-----------|-----------|
0 | 113 | 109 | 222 |
| 0.003 | 0.003 | |
| 0.509 | 0.491 | 0.712 |
| 0.715 | 0.708 | |
| 0.362 | 0.349 | |
-------------|-----------|-----------|-----------|
1 | 45 | 45 | 90 |
| 0.007 | 0.007 | |
| 0.500 | 0.500 | 0.288 |
| 0.285 | 0.292 | |
| 0.144 | 0.144 | |
-------------|-----------|-----------|-----------|
Column Total | 158 | 154 | 312 |
| 0.506 | 0.494 | |
-------------|-----------|-----------|-----------|
Cell Contents
|-------------------------|
| N |
| Chi-square contribution |
| N / Row Total |
| N / Col Total |
| N / Table Total |
|-------------------------|
Total Observations in Table: 312
| trt
edema | 1 | 2 | Row Total |
-------------|-----------|-----------|-----------|
0 | 132 | 131 | 263 |
| 0.011 | 0.011 | |
| 0.502 | 0.498 | 0.843 |
| 0.835 | 0.851 | |
| 0.423 | 0.420 | |
-------------|-----------|-----------|-----------|
0.5 | 16 | 13 | 29 |
| 0.118 | 0.121 | |
| 0.552 | 0.448 | 0.093 |
| 0.101 | 0.084 | |
| 0.051 | 0.042 | |
-------------|-----------|-----------|-----------|
1 | 10 | 10 | 20 |
| 0.002 | 0.002 | |
| 0.500 | 0.500 | 0.064 |
| 0.063 | 0.065 | |
| 0.032 | 0.032 | |
-------------|-----------|-----------|-----------|
Column Total | 158 | 154 | 312 |
| 0.506 | 0.494 | |
-------------|-----------|-----------|-----------|
Cell Contents
|-------------------------|
| N |
| Chi-square contribution |
| N / Row Total |
| N / Col Total |
| N / Table Total |
|-------------------------|
Total Observations in Table: 312
| trt
stage | 1 | 2 | Row Total |
-------------|-----------|-----------|-----------|
1 | 12 | 4 | 16 |
| 1.875 | 1.923 | |
| 0.750 | 0.250 | 0.051 |
| 0.076 | 0.026 | |
| 0.038 | 0.013 | |
-------------|-----------|-----------|-----------|
2 | 35 | 32 | 67 |
| 0.034 | 0.035 | |
| 0.522 | 0.478 | 0.215 |
| 0.222 | 0.208 | |
| 0.112 | 0.103 | |
-------------|-----------|-----------|-----------|
3 | 56 | 64 | 120 |
| 0.374 | 0.384 | |
| 0.467 | 0.533 | 0.385 |
| 0.354 | 0.416 | |
| 0.179 | 0.205 | |
-------------|-----------|-----------|-----------|
4 | 55 | 54 | 109 |
| 0.001 | 0.001 | |
| 0.505 | 0.495 | 0.349 |
| 0.348 | 0.351 | |
| 0.176 | 0.173 | |
-------------|-----------|-----------|-----------|
Column Total | 158 | 154 | 312 |
| 0.506 | 0.494 | |
-------------|-----------|-----------|-----------|
Stratified by trt
1 2 p test
n 158 154
time (mean (SD)) 2015.62 (1094.12) 1996.86 (1155.93) 0.883
age (mean (SD)) 51.42 (11.01) 48.58 (9.96) 0.018
bili (mean (SD)) 2.87 (3.63) 3.65 (5.28) 0.131
chol (mean (SD)) 365.01 (209.54) 373.88 (252.48) 0.748
albumin (mean (SD)) 3.52 (0.44) 3.52 (0.40) 0.874
copper (mean (SD)) 97.64 (90.59) 97.65 (80.49) 0.999
alk.phos (mean (SD)) 2021.30 (2183.44) 1943.01 (2101.69) 0.747
ast (mean (SD)) 120.21 (54.52) 124.97 (58.93) 0.460
trig (mean (SD)) 124.14 (71.54) 125.25 (58.52) 0.886
platelet (mean (SD)) 258.75 (100.32) 265.20 (90.73) 0.555
protime (mean (SD)) 10.65 (0.85) 10.80 (1.14) 0.197
Stratified by trt
1 2 p test
n 158 154
time (mean (SD)) 2015.62 (1094.12) 1996.86 (1155.93) 0.883
age (mean (SD)) 51.42 (11.01) 48.58 (9.96) 0.018
bili (mean (SD)) 2.87 (3.63) 3.65 (5.28) 0.131
chol (mean (SD)) 365.01 (209.54) 373.88 (252.48) 0.748
albumin (mean (SD)) 3.52 (0.44) 3.52 (0.40) 0.874
copper (mean (SD)) 97.64 (90.59) 97.65 (80.49) 0.999
alk.phos (mean (SD)) 2021.30 (2183.44) 1943.01 (2101.69) 0.747
ast (mean (SD)) 120.21 (54.52) 124.97 (58.93) 0.460
trig (mean (SD)) 124.14 (71.54) 125.25 (58.52) 0.886
platelet (mean (SD)) 258.75 (100.32) 265.20 (90.73) 0.555
protime (mean (SD)) 10.65 (0.85) 10.80 (1.14) 0.197
Overall
n 418
time (mean (SD)) 1917.78 (1104.67)
age (mean (SD)) 50.74 (10.45)
bili (mean (SD)) 3.22 (4.41)
chol (mean (SD)) 369.51 (231.94)
albumin (mean (SD)) 3.50 (0.42)
copper (mean (SD)) 97.65 (85.61)
alk.phos (mean (SD)) 1982.66 (2140.39)
ast (mean (SD)) 122.56 (56.70)
trig (mean (SD)) 124.70 (65.15)
platelet (mean (SD)) 257.02 (98.33)
protime (mean (SD)) 10.73 (1.02)
Overall
n 418
time (mean (SD)) 1917.78 (1104.67)
age (mean (SD)) 50.74 (10.45)
bili (mean (SD)) 3.22 (4.41)
chol (mean (SD)) 369.51 (231.94)
albumin (mean (SD)) 3.50 (0.42)
copper (mean (SD)) 97.65 (85.61)
alk.phos (mean (SD)) 1982.66 (2140.39)
ast (mean (SD)) 122.56 (56.70)
trig (mean (SD)) 124.70 (65.15)
platelet (mean (SD)) 257.02 (98.33)
protime (mean (SD)) 10.73 (1.02)
Stratified by trt:sex
1:m 2:m 1:f
n 21 15 137
time (mean (SD)) 1793.48 (1244.70) 2156.33 (1428.56) 2049.67 (1070.20)
age (mean (SD)) 55.57 (12.61) 57.09 (10.07) 50.78 (10.65)
bili (mean (SD)) 2.98 (2.11) 2.72 (2.46) 2.86 (3.81)
chol (mean (SD)) 403.43 (204.95) 301.00 (111.32) 358.24 (210.46)
albumin (mean (SD)) 3.63 (0.43) 3.50 (0.49) 3.50 (0.44)
copper (mean (SD)) 174.90 (105.33) 125.40 (89.18) 85.71 (82.27)
alk.phos (mean (SD)) 2486.16 (2385.32) 1734.45 (2478.07) 1950.04 (2151.35)
ast (mean (SD)) 128.71 (48.74) 112.58 (44.38) 118.91 (55.40)
trig (mean (SD)) 145.81 (56.62) 114.86 (39.59) 120.28 (73.41)
platelet (mean (SD)) 232.65 (97.38) 240.13 (73.93) 262.59 (100.53)
protime (mean (SD)) 10.84 (0.94) 11.23 (0.97) 10.62 (0.84)
Stratified by trt:sex
2:f p test
n 139
time (mean (SD)) 1979.65 (1127.52) 0.730
age (mean (SD)) 47.66 (9.54) <0.001
bili (mean (SD)) 3.75 (5.50) 0.394
chol (mean (SD)) 381.73 (262.26) 0.512
albumin (mean (SD)) 3.53 (0.39) 0.585
copper (mean (SD)) 94.64 (79.25) <0.001
alk.phos (mean (SD)) 1965.52 (2066.15) 0.706
ast (mean (SD)) 126.30 (60.27) 0.598
trig (mean (SD)) 126.38 (60.22) 0.370
platelet (mean (SD)) 267.95 (92.20) 0.362
protime (mean (SD)) 10.75 (1.15) 0.137
Stratified by trt:sex
1:m 2:m 1:f
n 21 15 137
time (mean (SD)) 1793.48 (1244.70) 2156.33 (1428.56) 2049.67 (1070.20)
age (mean (SD)) 55.57 (12.61) 57.09 (10.07) 50.78 (10.65)
bili (mean (SD)) 2.98 (2.11) 2.72 (2.46) 2.86 (3.81)
chol (mean (SD)) 403.43 (204.95) 301.00 (111.32) 358.24 (210.46)
albumin (mean (SD)) 3.63 (0.43) 3.50 (0.49) 3.50 (0.44)
copper (mean (SD)) 174.90 (105.33) 125.40 (89.18) 85.71 (82.27)
alk.phos (mean (SD)) 2486.16 (2385.32) 1734.45 (2478.07) 1950.04 (2151.35)
ast (mean (SD)) 128.71 (48.74) 112.58 (44.38) 118.91 (55.40)
trig (mean (SD)) 145.81 (56.62) 114.86 (39.59) 120.28 (73.41)
platelet (mean (SD)) 232.65 (97.38) 240.13 (73.93) 262.59 (100.53)
protime (mean (SD)) 10.84 (0.94) 11.23 (0.97) 10.62 (0.84)
Stratified by trt:sex
2:f p test
n 139
time (mean (SD)) 1979.65 (1127.52) 0.730
age (mean (SD)) 47.66 (9.54) <0.001
bili (mean (SD)) 3.75 (5.50) 0.394
chol (mean (SD)) 381.73 (262.26) 0.512
albumin (mean (SD)) 3.53 (0.39) 0.585
copper (mean (SD)) 94.64 (79.25) <0.001
alk.phos (mean (SD)) 1965.52 (2066.15) 0.706
ast (mean (SD)) 126.30 (60.27) 0.598
trig (mean (SD)) 126.38 (60.22) 0.370
platelet (mean (SD)) 267.95 (92.20) 0.362
protime (mean (SD)) 10.75 (1.15) 0.137
Stratified by trt
1 2 p test
n 158 154
time (mean (SD)) 2015.620 (1094.123) 1996.864 (1155.929) 0.88305
age (mean (SD)) 51.419 (11.007) 48.583 (9.958) 0.01767
bili (mean (SD)) 2.873 (3.629) 3.649 (5.282) 0.13094
chol (mean (SD)) 365.014 (209.544) 373.882 (252.485) 0.74799
albumin (mean (SD)) 3.516 (0.443) 3.524 (0.396) 0.87388
copper (mean (SD)) 97.643 (90.590) 97.654 (80.486) 0.99916
alk.phos (mean (SD)) 2021.297 (2183.436) 1943.010 (2101.687) 0.74726
ast (mean (SD)) 120.209 (54.521) 124.965 (58.931) 0.45970
trig (mean (SD)) 124.137 (71.539) 125.252 (58.521) 0.88604
platelet (mean (SD)) 258.750 (100.325) 265.204 (90.729) 0.55451
protime (mean (SD)) 10.653 (0.851) 10.800 (1.138) 0.19714
Stratified by trt
1 2 p test
n 158 154
time (mean (SD)) 2015.620 (1094.123) 1996.864 (1155.929) 0.88305
age (mean (SD)) 51.419 (11.007) 48.583 (9.958) 0.01767
bili (mean (SD)) 2.873 (3.629) 3.649 (5.282) 0.13094
chol (mean (SD)) 365.014 (209.544) 373.882 (252.485) 0.74799
albumin (mean (SD)) 3.516 (0.443) 3.524 (0.396) 0.87388
copper (mean (SD)) 97.643 (90.590) 97.654 (80.486) 0.99916
alk.phos (mean (SD)) 2021.297 (2183.436) 1943.010 (2101.687) 0.74726
ast (mean (SD)) 120.209 (54.521) 124.965 (58.931) 0.45970
trig (mean (SD)) 124.137 (71.539) 125.252 (58.521) 0.88604
platelet (mean (SD)) 258.750 (100.325) 265.204 (90.729) 0.55451
protime (mean (SD)) 10.653 (0.851) 10.800 (1.138) 0.19714
Stratified by trt
1 2
n 158 154
time (mean (SD)) 2015.62 (1094.12) 1996.86 (1155.93)
age (mean (SD)) 51.42 (11.01) 48.58 (9.96)
bili (mean (SD)) 2.87 (3.63) 3.65 (5.28)
chol (mean (SD)) 365.01 (209.54) 373.88 (252.48)
albumin (mean (SD)) 3.52 (0.44) 3.52 (0.40)
copper (mean (SD)) 97.64 (90.59) 97.65 (80.49)
alk.phos (mean (SD)) 2021.30 (2183.44) 1943.01 (2101.69)
ast (mean (SD)) 120.21 (54.52) 124.97 (58.93)
trig (mean (SD)) 124.14 (71.54) 125.25 (58.52)
platelet (mean (SD)) 258.75 (100.32) 265.20 (90.73)
protime (mean (SD)) 10.65 (0.85) 10.80 (1.14)
Stratified by trt
1 2
n 158 154
time (mean (SD)) 2015.62 (1094.12) 1996.86 (1155.93)
age (mean (SD)) 51.42 (11.01) 48.58 (9.96)
bili (mean (SD)) 2.87 (3.63) 3.65 (5.28)
chol (mean (SD)) 365.01 (209.54) 373.88 (252.48)
albumin (mean (SD)) 3.52 (0.44) 3.52 (0.40)
copper (mean (SD)) 97.64 (90.59) 97.65 (80.49)
alk.phos (mean (SD)) 2021.30 (2183.44) 1943.01 (2101.69)
ast (mean (SD)) 120.21 (54.52) 124.97 (58.93)
trig (mean (SD)) 124.14 (71.54) 125.25 (58.52)
platelet (mean (SD)) 258.75 (100.32) 265.20 (90.73)
protime (mean (SD)) 10.65 (0.85) 10.80 (1.14)
Stratified by trt
1 2
n 158 154
time (mean (SD)) 2015.62 (1094.12) 1996.86 (1155.93)
age (mean (SD)) 51.42 (11.01) 48.58 (9.96)
bili (median [IQR]) 1.40 [0.80, 3.20] 1.30 [0.72, 3.60]
chol (median [IQR]) 315.50 [247.75, 417.00] 303.50 [254.25, 377.00]
albumin (mean (SD)) 3.52 (0.44) 3.52 (0.40)
copper (median [IQR]) 73.00 [40.00, 121.00] 73.00 [43.00, 139.00]
alk.phos (median [IQR]) 1214.50 [840.75, 2028.00] 1283.00 [922.50, 1949.75]
ast (mean (SD)) 120.21 (54.52) 124.97 (58.93)
trig (median [IQR]) 106.00 [84.50, 146.00] 113.00 [84.50, 155.00]
platelet (mean (SD)) 258.75 (100.32) 265.20 (90.73)
protime (mean (SD)) 10.65 (0.85) 10.80 (1.14)
Stratified by trt
p test
n
time (mean (SD)) 0.883
age (mean (SD)) 0.018
bili (median [IQR]) 0.842 nonnorm
chol (median [IQR]) 0.544 nonnorm
albumin (mean (SD)) 0.874
copper (median [IQR]) 0.717 nonnorm
alk.phos (median [IQR]) 0.812 nonnorm
ast (mean (SD)) 0.460
trig (median [IQR]) 0.370 nonnorm
platelet (mean (SD)) 0.555
protime (mean (SD)) 0.197
Stratified by trt
1 2
n 158 154
time (mean (SD)) 2015.62 (1094.12) 1996.86 (1155.93)
age (mean (SD)) 51.42 (11.01) 48.58 (9.96)
bili (median [IQR]) 1.40 [0.80, 3.20] 1.30 [0.72, 3.60]
chol (median [IQR]) 315.50 [247.75, 417.00] 303.50 [254.25, 377.00]
albumin (mean (SD)) 3.52 (0.44) 3.52 (0.40)
copper (median [IQR]) 73.00 [40.00, 121.00] 73.00 [43.00, 139.00]
alk.phos (median [IQR]) 1214.50 [840.75, 2028.00] 1283.00 [922.50, 1949.75]
ast (mean (SD)) 120.21 (54.52) 124.97 (58.93)
trig (median [IQR]) 106.00 [84.50, 146.00] 113.00 [84.50, 155.00]
platelet (mean (SD)) 258.75 (100.32) 265.20 (90.73)
protime (mean (SD)) 10.65 (0.85) 10.80 (1.14)
Stratified by trt
p test
n
time (mean (SD)) 0.883
age (mean (SD)) 0.018
bili (median [IQR]) 0.842 nonnorm
chol (median [IQR]) 0.544 nonnorm
albumin (mean (SD)) 0.874
copper (median [IQR]) 0.717 nonnorm
alk.phos (median [IQR]) 0.812 nonnorm
ast (mean (SD)) 0.460
trig (median [IQR]) 0.370 nonnorm
platelet (mean (SD)) 0.555
protime (mean (SD)) 0.197
Stratified by trt
1
n 158
time (mean (SD)) 2015.62 (1094.12)
age (mean (SD)) 51.42 (11.01)
bili (median [range]) 1.40 [0.30, 20.00]
chol (median [range]) 315.50 [127.00, 1712.00]
albumin (mean (SD)) 3.52 (0.44)
copper (median [range]) 73.00 [9.00, 588.00]
alk.phos (median [range]) 1214.50 [369.00, 11552.00]
ast (mean (SD)) 120.21 (54.52)
trig (median [range]) 106.00 [33.00, 598.00]
platelet (mean (SD)) 258.75 (100.32)
protime (mean (SD)) 10.65 (0.85)
Stratified by trt
2 p test
n 154
time (mean (SD)) 1996.86 (1155.93) 0.883
age (mean (SD)) 48.58 (9.96) 0.018
bili (median [range]) 1.30 [0.30, 28.00] 0.842 nonnorm
chol (median [range]) 303.50 [120.00, 1775.00] 0.544 nonnorm
albumin (mean (SD)) 3.52 (0.40) 0.874
copper (median [range]) 73.00 [4.00, 558.00] 0.717 nonnorm
alk.phos (median [range]) 1283.00 [289.00, 13862.40] 0.812 nonnorm
ast (mean (SD)) 124.97 (58.93) 0.460
trig (median [range]) 113.00 [44.00, 432.00] 0.370 nonnorm
platelet (mean (SD)) 265.20 (90.73) 0.555
protime (mean (SD)) 10.80 (1.14) 0.197
Stratified by trt
1
n 158
time (mean (SD)) 2015.62 (1094.12)
age (mean (SD)) 51.42 (11.01)
bili (median [range]) 1.40 [0.30, 20.00]
chol (median [range]) 315.50 [127.00, 1712.00]
albumin (mean (SD)) 3.52 (0.44)
copper (median [range]) 73.00 [9.00, 588.00]
alk.phos (median [range]) 1214.50 [369.00, 11552.00]
ast (mean (SD)) 120.21 (54.52)
trig (median [range]) 106.00 [33.00, 598.00]
platelet (mean (SD)) 258.75 (100.32)
protime (mean (SD)) 10.65 (0.85)
Stratified by trt
2 p test
n 154
time (mean (SD)) 1996.86 (1155.93) 0.883
age (mean (SD)) 48.58 (9.96) 0.018
bili (median [range]) 1.30 [0.30, 28.00] 0.842 nonnorm
chol (median [range]) 303.50 [120.00, 1775.00] 0.544 nonnorm
albumin (mean (SD)) 3.52 (0.40) 0.874
copper (median [range]) 73.00 [4.00, 558.00] 0.717 nonnorm
alk.phos (median [range]) 1283.00 [289.00, 13862.40] 0.812 nonnorm
ast (mean (SD)) 124.97 (58.93) 0.460
trig (median [range]) 113.00 [44.00, 432.00] 0.370 nonnorm
platelet (mean (SD)) 265.20 (90.73) 0.555
protime (mean (SD)) 10.80 (1.14) 0.197
Stratified by trt
1 2 p test
n 158 154
time (mean (SD)) 2015.62 (1094.12) 1996.86 (1155.93) 0.883
age (mean (SD)) 51.42 (11.01) 48.58 (9.96) 0.018
bili (mean (SD)) 2.87 (3.63) 3.65 (5.28) 0.131
chol (mean (SD)) 365.01 (209.54) 373.88 (252.48) 0.748
albumin (mean (SD)) 3.52 (0.44) 3.52 (0.40) 0.874
copper (mean (SD)) 97.64 (90.59) 97.65 (80.49) 0.999
alk.phos (mean (SD)) 2021.30 (2183.44) 1943.01 (2101.69) 0.747
ast (mean (SD)) 120.21 (54.52) 124.97 (58.93) 0.460
trig (mean (SD)) 124.14 (71.54) 125.25 (58.52) 0.886
platelet (mean (SD)) 258.75 (100.32) 265.20 (90.73) 0.555
protime (mean (SD)) 10.65 (0.85) 10.80 (1.14) 0.197
Stratified by trt
1 2 p test
n 158 154
time (mean (SD)) 2015.62 (1094.12) 1996.86 (1155.93) 0.883
age (mean (SD)) 51.42 (11.01) 48.58 (9.96) 0.018
bili (mean (SD)) 2.87 (3.63) 3.65 (5.28) 0.131
chol (mean (SD)) 365.01 (209.54) 373.88 (252.48) 0.748
albumin (mean (SD)) 3.52 (0.44) 3.52 (0.40) 0.874
copper (mean (SD)) 97.64 (90.59) 97.65 (80.49) 0.999
alk.phos (mean (SD)) 2021.30 (2183.44) 1943.01 (2101.69) 0.747
ast (mean (SD)) 120.21 (54.52) 124.97 (58.93) 0.460
trig (mean (SD)) 124.14 (71.54) 125.25 (58.52) 0.886
platelet (mean (SD)) 258.75 (100.32) 265.20 (90.73) 0.555
protime (mean (SD)) 10.65 (0.85) 10.80 (1.14) 0.197
Stratified by trt
1 2 p test
n 158 154
time 2015.62 (1094.12) 1996.86 (1155.93) 0.883
age 51.42 (11.01) 48.58 (9.96) 0.018
bili 2.87 (3.63) 3.65 (5.28) 0.131
chol 365.01 (209.54) 373.88 (252.48) 0.748
albumin 3.52 (0.44) 3.52 (0.40) 0.874
copper 97.64 (90.59) 97.65 (80.49) 0.999
alk.phos 2021.30 (2183.44) 1943.01 (2101.69) 0.747
ast 120.21 (54.52) 124.97 (58.93) 0.460
trig 124.14 (71.54) 125.25 (58.52) 0.886
platelet 258.75 (100.32) 265.20 (90.73) 0.555
protime 10.65 (0.85) 10.80 (1.14) 0.197
Stratified by trt
1 2 p test
n 158 154
time 2015.62 (1094.12) 1996.86 (1155.93) 0.883
age 51.42 (11.01) 48.58 (9.96) 0.018
bili 2.87 (3.63) 3.65 (5.28) 0.131
chol 365.01 (209.54) 373.88 (252.48) 0.748
albumin 3.52 (0.44) 3.52 (0.40) 0.874
copper 97.64 (90.59) 97.65 (80.49) 0.999
alk.phos 2021.30 (2183.44) 1943.01 (2101.69) 0.747
ast 120.21 (54.52) 124.97 (58.93) 0.460
trig 124.14 (71.54) 125.25 (58.52) 0.886
platelet 258.75 (100.32) 265.20 (90.73) 0.555
protime 10.65 (0.85) 10.80 (1.14) 0.197
"Stratified by trt"
"" "1" "2" "p" "test"
"n" "158" "154" "" ""
"time (mean (SD))" "2015.62 (1094.12)" "1996.86 (1155.93)" "0.883" ""
"age (mean (SD))" "51.42 (11.01)" "48.58 (9.96)" "0.018" ""
"bili (mean (SD))" "2.87 (3.63)" "3.65 (5.28)" "0.131" ""
"chol (mean (SD))" "365.01 (209.54)" "373.88 (252.48)" "0.748" ""
"albumin (mean (SD))" "3.52 (0.44)" "3.52 (0.40)" "0.874" ""
"copper (mean (SD))" "97.64 (90.59)" "97.65 (80.49)" "0.999" ""
"alk.phos (mean (SD))" "2021.30 (2183.44)" "1943.01 (2101.69)" "0.747" ""
"ast (mean (SD))" "120.21 (54.52)" "124.97 (58.93)" "0.460" ""
"trig (mean (SD))" "124.14 (71.54)" "125.25 (58.52)" "0.886" ""
"platelet (mean (SD))" "258.75 (100.32)" "265.20 (90.73)" "0.555" ""
"protime (mean (SD))" "10.65 (0.85)" "10.80 (1.14)" "0.197" ""
"Stratified by trt"
"" "1" "2" "p" "test"
"n" "158" "154" "" ""
"time (mean (SD))" "2015.62 (1094.12)" "1996.86 (1155.93)" "0.883" ""
"age (mean (SD))" "51.42 (11.01)" "48.58 (9.96)" "0.018" ""
"bili (mean (SD))" "2.87 (3.63)" "3.65 (5.28)" "0.131" ""
"chol (mean (SD))" "365.01 (209.54)" "373.88 (252.48)" "0.748" ""
"albumin (mean (SD))" "3.52 (0.44)" "3.52 (0.40)" "0.874" ""
"copper (mean (SD))" "97.64 (90.59)" "97.65 (80.49)" "0.999" ""
"alk.phos (mean (SD))" "2021.30 (2183.44)" "1943.01 (2101.69)" "0.747" ""
"ast (mean (SD))" "120.21 (54.52)" "124.97 (58.93)" "0.460" ""
"trig (mean (SD))" "124.14 (71.54)" "125.25 (58.52)" "0.886" ""
"platelet (mean (SD))" "258.75 (100.32)" "265.20 (90.73)" "0.555" ""
"protime (mean (SD))" "10.65 (0.85)" "10.80 (1.14)" "0.197" ""
"Stratified by trt"
"" "Overall" "1"
"n" "418" "158"
"time (mean (SD))" "1917.78 (1104.67)" "2015.62 (1094.12)"
"age (mean (SD))" "50.74 (10.45)" "51.42 (11.01)"
"bili (mean (SD))" "3.22 (4.41)" "2.87 (3.63)"
"chol (mean (SD))" "369.51 (231.94)" "365.01 (209.54)"
"albumin (mean (SD))" "3.50 (0.42)" "3.52 (0.44)"
"copper (mean (SD))" "97.65 (85.61)" "97.64 (90.59)"
"alk.phos (mean (SD))" "1982.66 (2140.39)" "2021.30 (2183.44)"
"ast (mean (SD))" "122.56 (56.70)" "120.21 (54.52)"
"trig (mean (SD))" "124.70 (65.15)" "124.14 (71.54)"
"platelet (mean (SD))" "257.02 (98.33)" "258.75 (100.32)"
"protime (mean (SD))" "10.73 (1.02)" "10.65 (0.85)"
"Stratified by trt"
"" "2" "p" "test" "SMD"
"n" "154" "" "" ""
"time (mean (SD))" "1996.86 (1155.93)" "0.883" "" "0.017"
"age (mean (SD))" "48.58 (9.96)" "0.018" "" "0.270"
"bili (mean (SD))" "3.65 (5.28)" "0.131" "" "0.171"
"chol (mean (SD))" "373.88 (252.48)" "0.748" "" "0.038"
"albumin (mean (SD))" "3.52 (0.40)" "0.874" "" "0.018"
"copper (mean (SD))" "97.65 (80.49)" "0.999" "" "<0.001"
"alk.phos (mean (SD))" "1943.01 (2101.69)" "0.747" "" "0.037"
"ast (mean (SD))" "124.97 (58.93)" "0.460" "" "0.084"
"trig (mean (SD))" "125.25 (58.52)" "0.886" "" "0.017"
"platelet (mean (SD))" "265.20 (90.73)" "0.555" "" "0.067"
"protime (mean (SD))" "10.80 (1.14)" "0.197" "" "0.146"
"Stratified by trt"
"" "Overall" "1"
"n" "418" "158"
"time (mean (SD))" "1917.78 (1104.67)" "2015.62 (1094.12)"
"age (mean (SD))" "50.74 (10.45)" "51.42 (11.01)"
"bili (mean (SD))" "3.22 (4.41)" "2.87 (3.63)"
"chol (mean (SD))" "369.51 (231.94)" "365.01 (209.54)"
"albumin (mean (SD))" "3.50 (0.42)" "3.52 (0.44)"
"copper (mean (SD))" "97.65 (85.61)" "97.64 (90.59)"
"alk.phos (mean (SD))" "1982.66 (2140.39)" "2021.30 (2183.44)"
"ast (mean (SD))" "122.56 (56.70)" "120.21 (54.52)"
"trig (mean (SD))" "124.70 (65.15)" "124.14 (71.54)"
"platelet (mean (SD))" "257.02 (98.33)" "258.75 (100.32)"
"protime (mean (SD))" "10.73 (1.02)" "10.65 (0.85)"
"Stratified by trt"
"" "2" "p" "test" "SMD"
"n" "154" "" "" ""
"time (mean (SD))" "1996.86 (1155.93)" "0.883" "" "0.017"
"age (mean (SD))" "48.58 (9.96)" "0.018" "" "0.270"
"bili (mean (SD))" "3.65 (5.28)" "0.131" "" "0.171"
"chol (mean (SD))" "373.88 (252.48)" "0.748" "" "0.038"
"albumin (mean (SD))" "3.52 (0.40)" "0.874" "" "0.018"
"copper (mean (SD))" "97.65 (80.49)" "0.999" "" "<0.001"
"alk.phos (mean (SD))" "1943.01 (2101.69)" "0.747" "" "0.037"
"ast (mean (SD))" "124.97 (58.93)" "0.460" "" "0.084"
"trig (mean (SD))" "125.25 (58.52)" "0.886" "" "0.017"
"platelet (mean (SD))" "265.20 (90.73)" "0.555" "" "0.067"
"protime (mean (SD))" "10.80 (1.14)" "0.197" "" "0.146"
Stratified by trt:sex
Overall 1:m 2:m
n 418 21 15
time (mean (SD)) 1917.78 (1104.67) 1793.48 (1244.70) 2156.33 (1428.56)
age (mean (SD)) 50.74 (10.45) 55.57 (12.61) 57.09 (10.07)
bili (mean (SD)) 3.22 (4.41) 2.98 (2.11) 2.72 (2.46)
chol (mean (SD)) 369.51 (231.94) 403.43 (204.95) 301.00 (111.32)
albumin (mean (SD)) 3.50 (0.42) 3.63 (0.43) 3.50 (0.49)
copper (mean (SD)) 97.65 (85.61) 174.90 (105.33) 125.40 (89.18)
alk.phos (mean (SD)) 1982.66 (2140.39) 2486.16 (2385.32) 1734.45 (2478.07)
ast (mean (SD)) 122.56 (56.70) 128.71 (48.74) 112.58 (44.38)
trig (mean (SD)) 124.70 (65.15) 145.81 (56.62) 114.86 (39.59)
platelet (mean (SD)) 257.02 (98.33) 232.65 (97.38) 240.13 (73.93)
protime (mean (SD)) 10.73 (1.02) 10.84 (0.94) 11.23 (0.97)
Stratified by trt:sex
1:f 2:f p test
n 137 139
time (mean (SD)) 2049.67 (1070.20) 1979.65 (1127.52) 0.730
age (mean (SD)) 50.78 (10.65) 47.66 (9.54) <0.001
bili (mean (SD)) 2.86 (3.81) 3.75 (5.50) 0.394
chol (mean (SD)) 358.24 (210.46) 381.73 (262.26) 0.512
albumin (mean (SD)) 3.50 (0.44) 3.53 (0.39) 0.585
copper (mean (SD)) 85.71 (82.27) 94.64 (79.25) <0.001
alk.phos (mean (SD)) 1950.04 (2151.35) 1965.52 (2066.15) 0.706
ast (mean (SD)) 118.91 (55.40) 126.30 (60.27) 0.598
trig (mean (SD)) 120.28 (73.41) 126.38 (60.22) 0.370
platelet (mean (SD)) 262.59 (100.53) 267.95 (92.20) 0.362
protime (mean (SD)) 10.62 (0.84) 10.75 (1.15) 0.137
Stratified by trt:sex
Overall 1:m 2:m
n 418 21 15
time (mean (SD)) 1917.78 (1104.67) 1793.48 (1244.70) 2156.33 (1428.56)
age (mean (SD)) 50.74 (10.45) 55.57 (12.61) 57.09 (10.07)
bili (mean (SD)) 3.22 (4.41) 2.98 (2.11) 2.72 (2.46)
chol (mean (SD)) 369.51 (231.94) 403.43 (204.95) 301.00 (111.32)
albumin (mean (SD)) 3.50 (0.42) 3.63 (0.43) 3.50 (0.49)
copper (mean (SD)) 97.65 (85.61) 174.90 (105.33) 125.40 (89.18)
alk.phos (mean (SD)) 1982.66 (2140.39) 2486.16 (2385.32) 1734.45 (2478.07)
ast (mean (SD)) 122.56 (56.70) 128.71 (48.74) 112.58 (44.38)
trig (mean (SD)) 124.70 (65.15) 145.81 (56.62) 114.86 (39.59)
platelet (mean (SD)) 257.02 (98.33) 232.65 (97.38) 240.13 (73.93)
protime (mean (SD)) 10.73 (1.02) 10.84 (0.94) 11.23 (0.97)
Stratified by trt:sex
1:f 2:f p test
n 137 139
time (mean (SD)) 2049.67 (1070.20) 1979.65 (1127.52) 0.730
age (mean (SD)) 50.78 (10.65) 47.66 (9.54) <0.001
bili (mean (SD)) 2.86 (3.81) 3.75 (5.50) 0.394
chol (mean (SD)) 358.24 (210.46) 381.73 (262.26) 0.512
albumin (mean (SD)) 3.50 (0.44) 3.53 (0.39) 0.585
copper (mean (SD)) 85.71 (82.27) 94.64 (79.25) <0.001
alk.phos (mean (SD)) 1950.04 (2151.35) 1965.52 (2066.15) 0.706
ast (mean (SD)) 118.91 (55.40) 126.30 (60.27) 0.598
trig (mean (SD)) 120.28 (73.41) 126.38 (60.22) 0.370
platelet (mean (SD)) 262.59 (100.53) 267.95 (92.20) 0.362
protime (mean (SD)) 10.62 (0.84) 10.75 (1.15) 0.137
### Summary of continuous variables ###
strata: Overall
n miss p.miss mean sd median p25 p75 min max skew kurt
time 418 0 0.0 1918 1e+03 1730 1e+03 2614 41.0 4795 0.47 -0.5
age 418 0 0.0 51 1e+01 51 4e+01 58 26.3 78 0.09 -0.6
bili 418 0 0.0 3 4e+00 1 8e-01 3 0.3 28 2.72 8.1
chol 418 134 32.1 370 2e+02 310 2e+02 400 120.0 1775 3.41 14.3
albumin 418 0 0.0 3 4e-01 4 3e+00 4 2.0 5 -0.47 0.6
copper 418 108 25.8 98 9e+01 73 4e+01 123 4.0 588 2.30 7.6
alk.phos 418 106 25.4 1983 2e+03 1259 9e+02 1980 289.0 13862 2.99 9.7
ast 418 106 25.4 123 6e+01 115 8e+01 152 26.4 457 1.45 4.3
trig 418 136 32.5 125 7e+01 108 8e+01 151 33.0 598 2.52 11.8
platelet 418 11 2.6 257 1e+02 251 2e+02 318 62.0 721 0.63 0.9
protime 418 2 0.5 11 1e+00 11 1e+01 11 9.0 18 2.22 10.0
=======================================================================================
### Summary of categorical variables ###
strata: Overall
var n miss p.miss level freq percent cum.percent
status 418 0 0.0 0 232 55.5 55.5
1 25 6.0 61.5
2 161 38.5 100.0
sex 418 0 0.0 m 44 10.5 10.5
f 374 89.5 100.0
ascites 418 106 25.4 0 288 92.3 92.3
1 24 7.7 100.0
hepato 418 106 25.4 0 152 48.7 48.7
1 160 51.3 100.0
spiders 418 106 25.4 0 222 71.2 71.2
1 90 28.8 100.0
edema 418 0 0.0 0 354 84.7 84.7
0.5 44 10.5 95.2
1 20 4.8 100.0
stage 418 6 1.4 1 21 5.1 5.1
2 92 22.3 27.4
3 155 37.6 65.0
4 144 35.0 100.0
### Summary of continuous variables ###
strata: Overall
n miss p.miss mean sd median p25 p75 min max skew kurt
time 418 0 0.0 1918 1e+03 1730 1e+03 2614 41.0 4795 0.47 -0.5
age 418 0 0.0 51 1e+01 51 4e+01 58 26.3 78 0.09 -0.6
bili 418 0 0.0 3 4e+00 1 8e-01 3 0.3 28 2.72 8.1
chol 418 134 32.1 370 2e+02 310 2e+02 400 120.0 1775 3.41 14.3
albumin 418 0 0.0 3 4e-01 4 3e+00 4 2.0 5 -0.47 0.6
copper 418 108 25.8 98 9e+01 73 4e+01 123 4.0 588 2.30 7.6
alk.phos 418 106 25.4 1983 2e+03 1259 9e+02 1980 289.0 13862 2.99 9.7
ast 418 106 25.4 123 6e+01 115 8e+01 152 26.4 457 1.45 4.3
trig 418 136 32.5 125 7e+01 108 8e+01 151 33.0 598 2.52 11.8
platelet 418 11 2.6 257 1e+02 251 2e+02 318 62.0 721 0.63 0.9
protime 418 2 0.5 11 1e+00 11 1e+01 11 9.0 18 2.22 10.0
=======================================================================================
### Summary of categorical variables ###
strata: Overall
var n miss p.miss level freq percent cum.percent
status 418 0 0.0 0 232 55.5 55.5
1 25 6.0 61.5
2 161 38.5 100.0
sex 418 0 0.0 m 44 10.5 10.5
f 374 89.5 100.0
ascites 418 0 0.0 0 288 68.9 68.9
1 24 5.7 74.6
<NA> 106 25.4 100.0
hepato 418 0 0.0 0 152 36.4 36.4
1 160 38.3 74.6
<NA> 106 25.4 100.0
spiders 418 0 0.0 0 222 53.1 53.1
1 90 21.5 74.6
<NA> 106 25.4 100.0
edema 418 0 0.0 0 354 84.7 84.7
0.5 44 10.5 95.2
1 20 4.8 100.0
stage 418 0 0.0 1 21 5.0 5.0
2 92 22.0 27.0
3 155 37.1 64.1
4 144 34.4 98.6
<NA> 6 1.4 100.0
### Summary of continuous variables ###
trt: 1
n miss p.miss mean sd median p25 p75 min max skew kurt
time 158 0 0.0 2016 1e+03 1895 1e+03 2632 41.0 4556 0.41 -0.4
age 158 0 0.0 51 1e+01 52 4e+01 59 26.3 78 0.06 -0.5
bili 158 0 0.0 3 4e+00 1 8e-01 3 0.3 20 2.67 7.6
chol 158 18 11.4 365 2e+02 316 2e+02 417 127.0 1712 3.83 20.2
albumin 158 0 0.0 4 4e-01 4 3e+00 4 2.1 5 -0.40 0.3
copper 158 1 0.6 98 9e+01 73 4e+01 121 9.0 588 2.50 8.2
alk.phos 158 0 0.0 2021 2e+03 1214 8e+02 2028 369.0 11552 2.71 7.4
ast 158 0 0.0 120 5e+01 112 8e+01 152 26.4 338 1.09 1.6
trig 158 19 12.0 124 7e+01 106 8e+01 146 33.0 598 2.95 14.3
platelet 158 2 1.3 259 1e+02 255 2e+02 322 62.0 563 0.50 0.2
protime 158 0 0.0 11 9e-01 11 1e+01 11 9.0 14 1.10 1.6
------------------------------------------------------------
trt: 2
n miss p.miss mean sd median p25 p75 min max skew kurt
time 154 0 0.0 1997 1e+03 1811 1e+03 2771 51.0 4523 0.4 -0.7
age 154 0 0.0 49 1e+01 48 4e+01 56 30.6 75 0.2 -0.5
bili 154 0 0.0 4 5e+00 1 7e-01 4 0.3 28 2.7 7.3
chol 154 10 6.5 374 3e+02 304 3e+02 377 120.0 1775 3.1 11.1
albumin 154 0 0.0 4 4e-01 4 3e+00 4 2.0 4 -0.8 2.0
copper 154 1 0.6 98 8e+01 73 4e+01 139 4.0 558 2.0 6.6
alk.phos 154 0 0.0 1943 2e+03 1283 9e+02 1950 289.0 13862 3.3 12.8
ast 154 0 0.0 125 6e+01 117 8e+01 152 28.4 457 1.7 6.3
trig 154 11 7.1 125 6e+01 113 8e+01 155 44.0 432 1.7 5.5
platelet 154 2 1.3 265 9e+01 260 2e+02 322 71.0 487 0.2 -0.3
protime 154 0 0.0 11 1e+00 11 1e+01 11 9.2 17 1.9 6.4
p-values
pNormal pNonNormal
time 0.88304691 0.82661809
age 0.01767247 0.01962155
bili 0.13093942 0.84168460
chol 0.74799072 0.54433899
albumin 0.87388074 0.95045176
copper 0.99915849 0.71745444
alk.phos 0.74726165 0.81198200
ast 0.45969842 0.45892358
trig 0.88604213 0.36980434
platelet 0.55451136 0.45482564
protime 0.19714026 0.58802048
Standardize mean differences
1 vs 2
time 0.0166658751
age 0.2702619258
bili 0.1710905651
chol 0.0382210537
albumin 0.0180021838
copper 0.0001200022
alk.phos 0.0365323630
ast 0.0837836058
trig 0.0170615337
platelet 0.0674763888
protime 0.1460939117
=======================================================================================
### Summary of categorical variables ###
trt: 1
var n miss p.miss level freq percent cum.percent
status 158 0 0.0 0 83 52.5 52.5
1 10 6.3 58.9
2 65 41.1 100.0
sex 158 0 0.0 m 21 13.3 13.3
f 137 86.7 100.0
ascites 158 0 0.0 0 144 91.1 91.1
1 14 8.9 100.0
hepato 158 0 0.0 0 85 53.8 53.8
1 73 46.2 100.0
spiders 158 0 0.0 0 113 71.5 71.5
1 45 28.5 100.0
edema 158 0 0.0 0 132 83.5 83.5
0.5 16 10.1 93.7
1 10 6.3 100.0
stage 158 0 0.0 1 12 7.6 7.6
2 35 22.2 29.7
3 56 35.4 65.2
4 55 34.8 100.0
------------------------------------------------------------
trt: 2
var n miss p.miss level freq percent cum.percent
status 154 0 0.0 0 85 55.2 55.2
1 9 5.8 61.0
2 60 39.0 100.0
sex 154 0 0.0 m 15 9.7 9.7
f 139 90.3 100.0
ascites 154 0 0.0 0 144 93.5 93.5
1 10 6.5 100.0
hepato 154 0 0.0 0 67 43.5 43.5
1 87 56.5 100.0
spiders 154 0 0.0 0 109 70.8 70.8
1 45 29.2 100.0
edema 154 0 0.0 0 131 85.1 85.1
0.5 13 8.4 93.5
1 10 6.5 100.0
stage 154 0 0.0 1 4 2.6 2.6
2 32 20.8 23.4
3 64 41.6 64.9
4 54 35.1 100.0
p-values
pApprox pExact
status 0.89350975 0.88422188
sex 0.42122610 0.37743235
ascites 0.56728647 0.52558267
hepato 0.08820884 0.07137522
spiders 0.98466036 0.90113734
edema 0.87681949 0.89370131
stage 0.20129629 0.20455558
Standardize mean differences
1 vs 2
status 0.05375763
sex 0.11141161
ascites 0.08900618
hepato 0.20699413
spiders 0.01632844
edema 0.05811659
stage 0.24600834
### Summary of continuous variables ###
trt: 1
sex: m
n miss p.miss mean sd median p25 p75 min max skew kurt
time 21 0 0 1793 1e+03 1302 999 2386 140.0 4459 1.04 0.1
age 21 0 0 56 1e+01 56 46 66 33.5 78 -0.20 -0.7
bili 21 0 0 3 2e+00 2 1 4 0.6 7 1.02 -0.1
chol 21 0 0 403 2e+02 376 251 456 168.0 1000 1.33 2.2
albumin 21 0 0 4 4e-01 4 3 4 2.6 4 -0.97 0.3
copper 21 0 0 175 1e+02 158 100 225 25.0 444 1.08 1.0
alk.phos 21 0 0 2486 2e+03 1664 983 2496 516.0 10165 2.05 4.5
ast 21 0 0 129 5e+01 127 86 158 56.8 222 0.31 -0.9
trig 21 0 0 146 6e+01 142 107 194 55.0 242 0.16 -1.0
platelet 21 1 5 233 1e+02 228 148 314 70.0 394 -0.05 -1.2
protime 21 0 0 11 9e-01 11 10 11 9.7 14 2.11 6.8
------------------------------------------------------------
trt: 2
sex: m
n miss p.miss mean sd median p25 p75 min max skew kurt
time 15 0 0 2156 1e+03 1656 1054 3420 191.0 4427 0.3 -1.4
age 15 0 0 57 1e+01 53 49 66 43.9 75 0.5 -1.3
bili 15 0 0 3 2e+00 2 1 3 0.6 9 1.5 1.4
chol 15 1 7 301 1e+02 259 236 342 151.0 546 0.9 0.4
albumin 15 0 0 4 5e-01 4 3 4 2.3 4 -1.0 1.9
copper 15 0 0 125 9e+01 84 52 198 13.0 281 0.5 -1.1
alk.phos 15 0 0 1734 2e+03 1070 737 1212 577.0 10397 3.5 12.7
ast 15 0 0 113 4e+01 110 74 129 46.5 188 0.3 -0.8
trig 15 1 7 115 4e+01 108 90 137 49.0 188 0.4 -0.4
platelet 15 0 0 240 7e+01 214 190 294 119.0 360 0.2 -1.0
protime 15 0 0 11 1e+00 11 11 12 10.0 13 0.7 0.2
------------------------------------------------------------
trt: 1
sex: f
n miss p.miss mean sd median p25 p75 min max skew kurt
time 137 0 0.0 2050 1e+03 1945 1e+03 2644 41.0 4556 0.32 -0.4
age 137 0 0.0 51 1e+01 51 4e+01 57 26.3 77 0.05 -0.5
bili 137 0 0.0 3 4e+00 1 8e-01 3 0.3 20 2.65 7.1
chol 137 18 13.1 358 2e+02 309 2e+02 400 127.0 1712 4.28 23.8
albumin 137 0 0.0 3 4e-01 4 3e+00 4 2.1 5 -0.33 0.4
copper 137 1 0.7 86 8e+01 67 4e+01 105 9.0 588 3.18 13.9
alk.phos 137 0 0.0 1950 2e+03 1212 8e+02 1877 369.0 11552 2.88 8.4
ast 137 0 0.0 119 6e+01 108 7e+01 150 26.4 338 1.20 1.9
trig 137 19 13.9 120 7e+01 101 8e+01 134 33.0 598 3.28 16.0
platelet 137 1 0.7 263 1e+02 258 2e+02 322 62.0 563 0.57 0.3
protime 137 0 0.0 11 8e-01 11 1e+01 11 9.0 13 0.92 0.6
------------------------------------------------------------
trt: 2
sex: f
n miss p.miss mean sd median p25 p75 min max skew kurt
time 139 0 0.0 1980 1e+03 1832 1e+03 2717 51.0 4523 0.3 -0.6
age 139 0 0.0 48 1e+01 47 4e+01 55 30.6 71 0.2 -0.7
bili 139 0 0.0 4 5e+00 1 7e-01 4 0.3 28 2.6 6.5
chol 139 9 6.5 382 3e+02 306 3e+02 381 120.0 1775 3.0 10.1
albumin 139 0 0.0 4 4e-01 4 3e+00 4 2.0 4 -0.8 2.1
copper 139 1 0.7 95 8e+01 70 4e+01 127 4.0 558 2.2 8.3
alk.phos 139 0 0.0 1966 2e+03 1345 9e+02 1992 289.0 13862 3.4 13.6
ast 139 0 0.0 126 6e+01 118 8e+01 153 28.4 457 1.8 6.2
trig 139 10 7.2 126 6e+01 113 8e+01 157 44.0 432 1.7 5.3
platelet 139 2 1.4 268 9e+01 265 2e+02 324 71.0 487 0.2 -0.4
protime 139 0 0.0 11 1e+00 11 1e+01 11 9.2 17 2.0 7.2
p-values
pNormal pNonNormal
time 7.300496e-01 5.566440e-01
age 1.286381e-04 6.517437e-04
bili 3.937430e-01 2.049525e-01
chol 5.122223e-01 4.578773e-01
albumin 5.853926e-01 4.041206e-01
copper 6.237989e-05 4.712924e-05
alk.phos 7.063812e-01 1.801480e-01
ast 5.982898e-01 5.086616e-01
trig 3.701073e-01 5.827726e-02
platelet 3.624740e-01 4.451277e-01
protime 1.365463e-01 8.114383e-02
Standardize mean differences
average 1 vs 2 1 vs 3 1 vs 4 2 vs 3 2 vs 4
time 0.1556365 0.27083134 0.22071813 0.15677410 0.08450703 0.13729269
age 0.5214974 0.13353519 0.40993004 0.70700091 0.60864596 0.96133382
bili 0.1352025 0.11373946 0.04023105 0.18444097 0.04265701 0.24158721
chol 0.2950579 0.62108339 0.21756422 0.09219212 0.33996564 0.40072828
albumin 0.1637683 0.28262444 0.30878937 0.26228013 0.01074465 0.05159074
copper 0.5416574 0.50727571 0.94378898 0.86116098 0.46259003 0.36464167
alk.phos 0.1633259 0.30907333 0.23603622 0.23332162 0.09290687 0.10128012
ast 0.1818681 0.34614452 0.18797132 0.04399580 0.12602823 0.25929154
trig 0.2940632 0.63360898 0.38944815 0.33242327 0.09194315 0.22610097
platelet 0.2340433 0.08655951 0.30251429 0.37226635 0.25448008 0.33286083
protime 0.3283721 0.40162254 0.24596092 0.08476002 0.66430044 0.44433997
3 vs 4
time 0.06369595
age 0.30853876
bili 0.18855913
chol 0.09881382
albumin 0.06658036
copper 0.11048709
alk.phos 0.00733728
ast 0.12777729
trig 0.09085446
platelet 0.05557853
protime 0.12924857
=======================================================================================
### Summary of categorical variables ###
trt: 1
sex: m
var n miss p.miss level freq percent cum.percent
status 21 0 0.0 0 4 19.0 19.0
1 3 14.3 33.3
2 14 66.7 100.0
sex 21 0 0.0 m 21 100.0 100.0
f 0 0.0 100.0
ascites 21 0 0.0 0 20 95.2 95.2
1 1 4.8 100.0
hepato 21 0 0.0 0 9 42.9 42.9
1 12 57.1 100.0
spiders 21 0 0.0 0 18 85.7 85.7
1 3 14.3 100.0
edema 21 0 0.0 0 17 81.0 81.0
0.5 3 14.3 95.2
1 1 4.8 100.0
stage 21 0 0.0 1 2 9.5 9.5
2 4 19.0 28.6
3 7 33.3 61.9
4 8 38.1 100.0
------------------------------------------------------------
trt: 2
sex: m
var n miss p.miss level freq percent cum.percent
status 15 0 0.0 0 7 46.7 46.7
1 0 0.0 46.7
2 8 53.3 100.0
sex 15 0 0.0 m 15 100.0 100.0
f 0 0.0 100.0
ascites 15 0 0.0 0 13 86.7 86.7
1 2 13.3 100.0
hepato 15 0 0.0 0 6 40.0 40.0
1 9 60.0 100.0
spiders 15 0 0.0 0 14 93.3 93.3
1 1 6.7 100.0
edema 15 0 0.0 0 12 80.0 80.0
0.5 1 6.7 86.7
1 2 13.3 100.0
stage 15 0 0.0 1 1 6.7 6.7
2 2 13.3 20.0
3 5 33.3 53.3
4 7 46.7 100.0
------------------------------------------------------------
trt: 1
sex: f
var n miss p.miss level freq percent cum.percent
status 137 0 0.0 0 79 57.7 57.7
1 7 5.1 62.8
2 51 37.2 100.0
sex 137 0 0.0 m 0 0.0 0.0
f 137 100.0 100.0
ascites 137 0 0.0 0 124 90.5 90.5
1 13 9.5 100.0
hepato 137 0 0.0 0 76 55.5 55.5
1 61 44.5 100.0
spiders 137 0 0.0 0 95 69.3 69.3
1 42 30.7 100.0
edema 137 0 0.0 0 115 83.9 83.9
0.5 13 9.5 93.4
1 9 6.6 100.0
stage 137 0 0.0 1 10 7.3 7.3
2 31 22.6 29.9
3 49 35.8 65.7
4 47 34.3 100.0
------------------------------------------------------------
trt: 2
sex: f
var n miss p.miss level freq percent cum.percent
status 139 0 0.0 0 78 56.1 56.1
1 9 6.5 62.6
2 52 37.4 100.0
sex 139 0 0.0 m 0 0.0 0.0
f 139 100.0 100.0
ascites 139 0 0.0 0 131 94.2 94.2
1 8 5.8 100.0
hepato 139 0 0.0 0 61 43.9 43.9
1 78 56.1 100.0
spiders 139 0 0.0 0 95 68.3 68.3
1 44 31.7 100.0
edema 139 0 0.0 0 119 85.6 85.6
0.5 12 8.6 94.2
1 8 5.8 100.0
stage 139 0 0.0 1 3 2.2 2.2
2 30 21.6 23.7
3 59 42.4 66.2
4 47 33.8 100.0
p-values
pApprox pExact
status 3.269881e-02 2.420814e-02
sex 2.514569e-67 4.934035e-48
ascites 5.156942e-01 4.354075e-01
hepato 2.080568e-01 2.048012e-01
spiders 8.898575e-02 8.569292e-02
edema 9.058420e-01 8.483322e-01
stage 6.463005e-01 NA
Standardize mean differences
average 1 vs 2 1 vs 3 1 vs 4 2 vs 3 2 vs 4
status 0.5770647 0.79644734 0.8748771 0.83097631 0.4375075 0.46214324
sex NaN 0.00000000 NaN NaN NaN NaN
ascites 0.1755851 0.30219043 0.1845375 0.04452096 0.1211310 0.26007640
hepato 0.1598214 0.05802589 0.2544151 0.02073917 0.3135916 0.07878788
spiders 0.4018377 0.25073566 0.3999925 0.42200838 0.6471968 0.66954801
edema 0.2122338 0.37625250 0.1624118 0.18063879 0.2420277 0.26502087
stage 0.2773411 0.21945509 0.1333844 0.35632272 0.3000785 0.39205566
3 vs 4
status 0.06043662
sex 0.00000000
ascites 0.14105454
hepato 0.23336861
spiders 0.02154469
edema 0.04705137
stage 0.26275030
### Summary of continuous variables ###
trt: 1
sex: m
n miss p.miss mean sd median p25 p75 min max skew kurt
time 21 0 0 1793 1e+03 1302 999 2386 140 4459 1.0 0.1
age 21 0 0 56 1e+01 56 46 66 33 78 -0.2 -0.7
protime 21 0 0 11 9e-01 11 10 11 10 14 2.1 6.8
------------------------------------------------------------
trt: 2
sex: m
n miss p.miss mean sd median p25 p75 min max skew kurt
time 15 0 0 2156 1429 1656 1054 3420 191 4427 0.3 -1.4
age 15 0 0 57 10 53 49 66 44 75 0.5 -1.3
protime 15 0 0 11 1 11 11 12 10 13 0.7 0.2
------------------------------------------------------------
trt: 1
sex: f
n miss p.miss mean sd median p25 p75 min max skew kurt
time 137 0 0 2050 1e+03 1945 1293 2644 41 4556 0.32 -0.4
age 137 0 0 51 1e+01 51 43 57 26 77 0.05 -0.5
protime 137 0 0 11 8e-01 11 10 11 9 13 0.92 0.6
------------------------------------------------------------
trt: 2
sex: f
n miss p.miss mean sd median p25 p75 min max skew kurt
time 139 0 0 1980 1128 1832 1157 2717 51 4523 0.3 -0.6
age 139 0 0 48 10 47 41 55 31 71 0.2 -0.7
protime 139 0 0 11 1 11 10 11 9 17 2.0 7.2
p-values
pNormal pNonNormal
time 0.7300495976 0.5566439797
age 0.0001286381 0.0006517437
protime 0.1365463300 0.0811438294
Standardize mean differences
average 1 vs 2 1 vs 3 1 vs 4 2 vs 3 2 vs 4
time 0.1556365 0.2708313 0.2207181 0.15677410 0.08450703 0.1372927
age 0.5214974 0.1335352 0.4099300 0.70700091 0.60864596 0.9613338
protime 0.3283721 0.4016225 0.2459609 0.08476002 0.66430044 0.4443400
3 vs 4
time 0.06369595
age 0.30853876
protime 0.12924857
### Summary of categorical variables ###
trt: 1
sex: m
var n miss p.miss level freq percent cum.percent
status 21 0 0.0 0 4 19.0 19.0
1 3 14.3 33.3
2 14 66.7 100.0
trt 21 0 0.0 1 21 100.0 100.0
2 0 0.0 100.0
sex 21 0 0.0 m 21 100.0 100.0
f 0 0.0 100.0
------------------------------------------------------------
trt: 2
sex: m
var n miss p.miss level freq percent cum.percent
status 15 0 0.0 0 7 46.7 46.7
1 0 0.0 46.7
2 8 53.3 100.0
trt 15 0 0.0 1 0 0.0 0.0
2 15 100.0 100.0
sex 15 0 0.0 m 15 100.0 100.0
f 0 0.0 100.0
------------------------------------------------------------
trt: 1
sex: f
var n miss p.miss level freq percent cum.percent
status 137 0 0.0 0 79 57.7 57.7
1 7 5.1 62.8
2 51 37.2 100.0
trt 137 0 0.0 1 137 100.0 100.0
2 0 0.0 100.0
sex 137 0 0.0 m 0 0.0 0.0
f 137 100.0 100.0
------------------------------------------------------------
trt: 2
sex: f
var n miss p.miss level freq percent cum.percent
status 139 0 0.0 0 78 56.1 56.1
1 9 6.5 62.6
2 52 37.4 100.0
trt 139 0 0.0 1 0 0.0 0.0
2 139 100.0 100.0
sex 139 0 0.0 m 0 0.0 0.0
f 139 100.0 100.0
p-values
pApprox pExact
status 3.269881e-02 2.420814e-02
trt 2.514569e-67 2.724125e-93
sex 2.514569e-67 4.934035e-48
Standardize mean differences
average 1 vs 2 1 vs 3 1 vs 4 2 vs 3 2 vs 4 3 vs 4
status 0.5770647 0.7964473 0.8748771 0.8309763 0.4375075 0.4621432 0.06043662
trt NaN NaN 0.0000000 NaN NaN 0.0000000 NaN
sex NaN 0.0000000 NaN NaN NaN NaN 0.00000000
average 1 vs 2 1 vs 3 1 vs 4 2 vs 3 2 vs 4
time 0.1556365 0.27083134 0.22071813 0.15677410 0.08450703 0.13729269
status 0.5770647 0.79644734 0.87487707 0.83097631 0.43750751 0.46214324
age 0.5214974 0.13353519 0.40993004 0.70700091 0.60864596 0.96133382
sex NaN 0.00000000 NaN NaN NaN NaN
ascites 0.1755851 0.30219043 0.18453749 0.04452096 0.12113103 0.26007640
hepato 0.1598214 0.05802589 0.25441512 0.02073917 0.31359163 0.07878788
spiders 0.4018377 0.25073566 0.39999254 0.42200838 0.64719678 0.66954801
edema 0.2122338 0.37625250 0.16241184 0.18063879 0.24202772 0.26502087
bili 0.1352025 0.11373946 0.04023105 0.18444097 0.04265701 0.24158721
chol 0.2950579 0.62108339 0.21756422 0.09219212 0.33996564 0.40072828
albumin 0.1637683 0.28262444 0.30878937 0.26228013 0.01074465 0.05159074
copper 0.5416574 0.50727571 0.94378898 0.86116098 0.46259003 0.36464167
alk.phos 0.1633259 0.30907333 0.23603622 0.23332162 0.09290687 0.10128012
ast 0.1818681 0.34614452 0.18797132 0.04399580 0.12602823 0.25929154
trig 0.2940632 0.63360898 0.38944815 0.33242327 0.09194315 0.22610097
platelet 0.2340433 0.08655951 0.30251429 0.37226635 0.25448008 0.33286083
protime 0.3283721 0.40162254 0.24596092 0.08476002 0.66430044 0.44433997
stage 0.2773411 0.21945509 0.13338440 0.35632272 0.30007852 0.39205566
3 vs 4
time 0.06369595
status 0.06043662
age 0.30853876
sex 0.00000000
ascites 0.14105454
hepato 0.23336861
spiders 0.02154469
edema 0.04705137
bili 0.18855913
chol 0.09881382
albumin 0.06658036
copper 0.11048709
alk.phos 0.00733728
ast 0.12777729
trig 0.09085446
platelet 0.05557853
protime 0.12924857
stage 0.26275030
average 1 vs 2 1 vs 3 1 vs 4 2 vs 3 2 vs 4
HI_CHOL 0.07290304 0.06404806 0.07986822 0.006024398 0.14361148 0.07003988
race NaN NaN NaN NaN NaN NaN
agecat 0.26102029 0.47958417 0.21054511 0.163093544 0.26927031 0.33972601
RIAGENDR 0.06902841 0.04460885 0.11590734 0.111246698 0.07120651 0.06655532
3 vs 4
HI_CHOL 0.073826228
race NaN
agecat 0.103902581
RIAGENDR 0.004645715
exp(coef) [confint] p
trt 1.03 [0.72, 1.47] 0.891
age 1.03 [1.01, 1.05] 0.005
albumin 0.26 [0.17, 0.41] <0.001
ascites 2.93 [1.68, 5.11] <0.001
exp(coef) [confint] p
trt 1.03 [0.72, 1.47] 0.891
age 1.03 [1.01, 1.05] 0.005
albumin 0.26 [0.17, 0.41] <0.001
ascites 2.93 [1.68, 5.11] <0.001
exp(coef) [confint] p
(Intercept) 4.81558 [0.26099, 93.77267] 0.293
trt 1.05879 [0.63994, 1.75622] 0.824
age 1.03850 [1.01306, 1.06547] 0.003
albumin 0.31078 [0.15316, 0.60752] 0.001
ascites 19.05020 [3.69390, 349.54310] 0.005
exp(coef) [confint] p
(Intercept) 4.81558 [0.25650, 90.40912] 0.293
trt 1.05879 [0.63975, 1.75230] 0.824
age 1.03850 [1.01271, 1.06494] 0.003
albumin 0.31078 [0.15640, 0.61757] 0.001
ascites 19.05020 [2.44625, 148.35373] 0.005
coef [confint] p
(Intercept) -1194.06334 [-2499.63435, 111.50767] 0.073
trt -50.39655 [-275.96185, 175.16874] 0.661
age -2.97371 [-14.01246, 8.06504] 0.596
albumin 987.37770 [695.98678, 1278.76862] <0.001
ascites -664.69235 [-1126.85877, -202.52592] 0.005
coef [confint] p
(Intercept) -1194.06334 [-2494.48743, 106.36074] 0.073
trt -50.39655 [-275.07261, 174.27950] 0.661
age -2.97371 [-13.96894, 8.02152] 0.596
albumin 987.37770 [697.13553, 1277.61988] <0.001
ascites -664.69235 [-1125.03679, -204.34791] 0.005
exp(coef) [confint] p
(Intercept) 2.82698 [2.64169, 3.02526] <0.001
trt 0.82689 [0.75758, 0.90254] <0.001
day 0.96758 [0.96225, 0.97295] <0.001
coef [confint] p
(Intercept) 2.70219 [2.51140, 2.89298] <0.001
trt -0.36806 [-0.57681, -0.15930] 0.001
day -0.06464 [-0.07910, -0.05017] <0.001
### The lme4 version is 1.1-23
coef [confint] p
(Intercept) 2.70219 [2.51320, 2.89118] NA
trt -0.36806 [-0.57306, -0.16305] NA
day -0.06464 [-0.07905, -0.05022] NA
coef [confint] p
(Intercept) 2.70219 [2.51320, 2.89118] <0.001
trt -0.36806 [-0.57306, -0.16305] 0.001
day -0.06464 [-0.07905, -0.05022] <0.001
exp(coef) [confint] p
(Intercept) 2.82371 [2.31045, 3.43231] <0.001
trt 0.82903 [0.70232, 0.97777] 0.026
day 0.96758 [0.94787, 0.98762] 0.002
-- 1. Failure: ModuleFormatPValues: alignes output vertically (@test-modules-pri
ModuleFormatPValues(pValues = eg_p, pDigits = 1) not equal to c("<0.1", " 0.1", " 0.1", " 0.9", " 1.0", " 1.0", " NA", " NaN").
1/8 mismatches
x[3]: " 0.2"
y[3]: " 0.1"
-- 2. Failure: ModuleConvertNormal: returns a column of numeric mean and a forma
ModuleConvertNormal(eg_mat, digits = 0) not equal to data.frame(col1 = eg_mean, col2 = " (2140)").
Component "col2": Modes: character, numeric
Component "col2": Attributes: < target is NULL, current is list >
Component "col2": target is character, current is factor
-- 3. Failure: ModuleConvertNormal: returns a column of numeric mean and a forma
ModuleConvertNormal(eg_mat, digits = 1) not equal to data.frame(col1 = eg_mean, col2 = " (2140.4)").
Component "col2": Modes: character, numeric
Component "col2": Attributes: < target is NULL, current is list >
Component "col2": target is character, current is factor
-- 4. Failure: ModuleConvertNormal: returns a column of numeric mean and a forma
ModuleConvertNormal(eg_mat, digits = 2) not equal to data.frame(col1 = eg_mean, col2 = " (2140.39)").
Component "col2": Modes: character, numeric
Component "col2": Attributes: < target is NULL, current is list >
Component "col2": target is character, current is factor
-- 5. Failure: ModuleConvertNormal: returns a column of numeric mean and a forma
ModuleConvertNormal(eg_mat, digits = 3) not equal to data.frame(col1 = eg_mean, col2 = " (2140.389)").
Component "col2": Modes: character, numeric
Component "col2": Attributes: < target is NULL, current is list >
Component "col2": target is character, current is factor
-- 6. Failure: ModuleConvertNormal: respects formatOptions (@test-modules-print.
ModuleConvertNormal(...) not equal to data.frame(col1 = eg_mean, col2 = " (2,140)").
Component "col2": Modes: character, numeric
Component "col2": Attributes: < target is NULL, current is list >
Component "col2": target is character, current is factor
-- 7. Failure: ModuleConvertNormal: respects formatOptions (@test-modules-print.
ModuleConvertNormal(...) not equal to data.frame(col1 = eg_mean, col2 = " (2,140D4)").
Component "col2": Modes: character, numeric
Component "col2": Attributes: < target is NULL, current is list >
Component "col2": target is character, current is factor
-- 8. Failure: ModuleConvertNormal: respects formatOptions (@test-modules-print.
ModuleConvertNormal(...) not equal to data.frame(col1 = eg_mean, col2 = " (2,140D39)").
Component "col2": Modes: character, numeric
Component "col2": Attributes: < target is NULL, current is list >
Component "col2": target is character, current is factor
-- 9. Failure: ModuleConvertNormal: respects formatOptions (@test-modules-print.
ModuleConvertNormal(...) not equal to data.frame(col1 = eg_mean, col2 = " (2,140D389)").
Component "col2": Modes: character, numeric
Component "col2": Attributes: < target is NULL, current is list >
Component "col2": target is character, current is factor
-- 10. Failure: ModuleConvertNonNormal: returns a column of numeric mean and a f
ModuleConvertNonNormal(eg_mat, digits = 0) not equal to data.frame(col1 = eg_median, col2 = " [872, 1980]").
Component "col2": Modes: character, numeric
Component "col2": Attributes: < target is NULL, current is list >
Component "col2": target is character, current is factor
-- 11. Failure: ModuleConvertNonNormal: returns a column of numeric mean and a f
ModuleConvertNonNormal(eg_mat, digits = 1) not equal to data.frame(col1 = eg_median, col2 = " [871.5, 1980.0]").
Component "col2": Modes: character, numeric
Component "col2": Attributes: < target is NULL, current is list >
Component "col2": target is character, current is factor
-- 12. Failure: ModuleConvertNonNormal: returns a column of numeric mean and a f
ModuleConvertNonNormal(eg_mat, digits = 2) not equal to data.frame(col1 = eg_median, col2 = " [871.50, 1980.00]").
Component "col2": Modes: character, numeric
Component "col2": Attributes: < target is NULL, current is list >
Component "col2": target is character, current is factor
-- 13. Failure: ModuleConvertNonNormal: returns a column of numeric mean and a f
ModuleConvertNonNormal(eg_mat, digits = 3) not equal to data.frame(col1 = eg_median, col2 = " [871.500, 1980.000]").
Component "col2": Modes: character, numeric
Component "col2": Attributes: < target is NULL, current is list >
Component "col2": target is character, current is factor
-- 14. Failure: ModuleConvertNonNormal: respects formatOptions (@test-modules-pr
ModuleConvertNonNormal(...) not equal to data.frame(col1 = eg_median, col2 = " [872, 1,980]").
Component "col2": Modes: character, numeric
Component "col2": Attributes: < target is NULL, current is list >
Component "col2": target is character, current is factor
-- 15. Failure: ModuleConvertNonNormal: respects formatOptions (@test-modules-pr
ModuleConvertNonNormal(...) not equal to data.frame(col1 = eg_median, col2 = " [871D5, 1,980D0]").
Component "col2": Modes: character, numeric
Component "col2": Attributes: < target is NULL, current is list >
Component "col2": target is character, current is factor
-- 16. Failure: ModuleConvertNonNormal: respects formatOptions (@test-modules-pr
ModuleConvertNonNormal(...) not equal to data.frame(col1 = eg_median, col2 = " [871D50, 1,980D00]").
Component "col2": Modes: character, numeric
Component "col2": Attributes: < target is NULL, current is list >
Component "col2": target is character, current is factor
-- 17. Failure: ModuleConvertNonNormal: respects formatOptions (@test-modules-pr
ModuleConvertNonNormal(...) not equal to data.frame(col1 = eg_median, col2 = " [871D500, 1,980D000]").
Component "col2": Modes: character, numeric
Component "col2": Attributes: < target is NULL, current is list >
Component "col2": target is character, current is factor
### Summary of continuous variables ###
HI_CHOL: 0
RIAGENDR: 1
n miss p.miss mean sd median p25 p75 min max skew kurt
race 3526 0 0 2 0.9 2 1 2 1 4 0.6 -0.3
------------------------------------------------------------
HI_CHOL: 1
RIAGENDR: 1
n miss p.miss mean sd median p25 p75 min max skew kurt
race 363 0 0 2 0.9 2 1 2 1 4 0.8 -0.1
------------------------------------------------------------
HI_CHOL: 0
RIAGENDR: 2
n miss p.miss mean sd median p25 p75 min max skew kurt
race 3533 0 0 2 0.9 2 1 2 1 4 0.6 -0.4
------------------------------------------------------------
HI_CHOL: 1
RIAGENDR: 2
n miss p.miss mean sd median p25 p75 min max skew kurt
race 424 0 0 2 0.8 2 1 2 1 4 0.7 0.6
p-values
pNormal pNonNormal
race 0.5071597 0.5761282
Standardize mean differences
average 1 vs 2 1 vs 3 1 vs 4 2 vs 3 2 vs 4
race 0.04247045 0.03492105 0.0006074061 0.07524267 0.03396878 0.03638678
3 vs 4
race 0.073696
=======================================================================================
### Summary of categorical variables ###
HI_CHOL: 0
RIAGENDR: 1
var n miss p.miss level freq percent cum.percent
agecat 3526 0 0.0 (0,19] 1119 31.7 31.7
(19,39] 797 22.6 54.3
(39,59] 775 22.0 76.3
(59,Inf] 835 23.7 100.0
------------------------------------------------------------
HI_CHOL: 1
RIAGENDR: 1
var n miss p.miss level freq percent cum.percent
agecat 363 0 0.0 (0,19] 10 2.8 2.8
(19,39] 88 24.2 27.0
(39,59] 173 47.7 74.7
(59,Inf] 92 25.3 100.0
------------------------------------------------------------
HI_CHOL: 0
RIAGENDR: 2
var n miss p.miss level freq percent cum.percent
agecat 3533 0 0.0 (0,19] 1015 28.7 28.7
(19,39] 950 26.9 55.6
(39,59] 796 22.5 78.1
(59,Inf] 772 21.9 100.0
------------------------------------------------------------
HI_CHOL: 1
RIAGENDR: 2
var n miss p.miss level freq percent cum.percent
agecat 424 0 0.0 (0,19] 6 1.4 1.4
(19,39] 70 16.5 17.9
(39,59] 167 39.4 57.3
(59,Inf] 181 42.7 100.0
p-values
pApprox pExact
agecat 9.387606e-89 NA
Standardize mean differences
average 1 vs 2 1 vs 3 1 vs 4 2 vs 3 2 vs 4 3 vs 4
agecat 0.702331 0.9040822 0.109801 0.985333 0.8536402 0.3838583 0.9772713
Stratified by HI_CHOL:RIAGENDR
0:1 1:1 0:2 1:2 p test
n 3526 363 3533 424
race (mean (SD)) 1.98 (0.85) 1.95 (0.90) 1.98 (0.87) 1.92 (0.76) 0.507
Stratified by HI_CHOL:RIAGENDR
0:1 1:1 0:2 1:2 p
n 3526 363 3533 424
race (mean (SD)) 1.98 (0.85) 1.95 (0.90) 1.98 (0.87) 1.92 (0.76) 0.507
agecat (%) <0.001
(0,19] 1119 (31.7) 10 ( 2.8) 1015 (28.7) 6 ( 1.4)
(19,39] 797 (22.6) 88 (24.2) 950 (26.9) 70 (16.5)
(39,59] 775 (22.0) 173 (47.7) 796 (22.5) 167 (39.4)
(59,Inf] 835 (23.7) 92 (25.3) 772 (21.9) 181 (42.7)
Stratified by HI_CHOL:RIAGENDR
test SMD
n
race (mean (SD)) 0.042
agecat (%) 0.702
(0,19]
(19,39]
(39,59]
(59,Inf]
Error in solve.default(Vmat) :
Lapack routine dgesv: system is exactly singular: U[4,4] = 0
Overall Missing
n 450.01
E (mean (SD)) 2.00 (0.82) 0.0
C (mean (SD)) 2.13 (0.88) 0.0
Y = 1 (%) 177.0 (39.4) 0.2
C1 = 1 (%) 150.0 (33.3) 0.0
C2 (mean (SD)) 0.47 (0.50) 0.0
Overall Missing
n 450.01
E (mean (SD)) 2.00 (0.82) 0.0
C (mean (SD)) 2.13 (0.88) 0.0
Y (%) 0.2
0 272.7 (60.6)
1 177.0 (39.3)
NA 0.3 ( 0.1)
C1 = 1 (%) 150.0 (33.3) 0.0
C2 (mean (SD)) 0.47 (0.50) 0.0
Stratified by E
1 2 3 p test
n 150.01 150.00 150.00
E (mean (SD)) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00) <0.001
C (mean (SD)) 2.13 (0.89) 2.13 (0.89) 2.13 (0.89) 1.000
Y = 1 (%) 59.0 (39.4) 59.0 (39.3) 59.0 (39.3) 1.000
C1 = 1 (%) 50.0 (33.3) 50.0 (33.3) 50.0 (33.3) 1.000
C2 (mean (SD)) 0.47 (0.50) 0.47 (0.50) 0.47 (0.50) 1.000
Stratified by E
Missing
n
E (mean (SD)) 0.0
C (mean (SD)) 0.0
Y = 1 (%) 0.2
C1 = 1 (%) 0.0
C2 (mean (SD)) 0.0
Stratified by E:C1
1:0 2:0 3:0 1:1
n 100.01 100.00 100.00 50.00
E (mean (SD)) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00) 1.00 (0.00)
C (mean (SD)) 1.60 (0.49) 1.60 (0.49) 1.60 (0.49) 3.20 (0.40)
Y = 1 (%) 22.0 (22.1) 22.0 (22.0) 22.0 (22.0) 37.0 ( 74.0)
C1 = 1 (%) 0.0 ( 0.0) 0.0 ( 0.0) 0.0 ( 0.0) 50.0 (100.0)
C2 (mean (SD)) 0.60 (0.49) 0.60 (0.49) 0.60 (0.49) 0.20 (0.40)
Stratified by E:C1
2:1 3:1 p test Missing
n 50.00 50.00
E (mean (SD)) 2.00 (0.00) 3.00 (0.00) <0.001 0.0
C (mean (SD)) 3.20 (0.40) 3.20 (0.40) <0.001 0.0
Y = 1 (%) 37.0 ( 74.0) 37.0 ( 74.0) <0.001 0.2
C1 = 1 (%) 50.0 (100.0) 50.0 (100.0) <0.001 0.0
C2 (mean (SD)) 0.20 (0.40) 0.20 (0.40) <0.001 0.0
Stratified by E
Overall 1 2 3
n 450.01 150.01 150.00 150.00
E (mean (SD)) 2.00 (0.82) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00)
C (mean (SD)) 2.13 (0.88) 2.13 (0.89) 2.13 (0.89) 2.13 (0.89)
Y = 1 (%) 177.0 (39.4) 59.0 (39.4) 59.0 (39.3) 59.0 (39.3)
C1 = 1 (%) 150.0 (33.3) 50.0 (33.3) 50.0 (33.3) 50.0 (33.3)
C2 (mean (SD)) 0.47 (0.50) 0.47 (0.50) 0.47 (0.50) 0.47 (0.50)
Stratified by E
p test Missing
n
E (mean (SD)) <0.001 0.0
C (mean (SD)) 1.000 0.0
Y = 1 (%) 1.000 0.2
C1 = 1 (%) 1.000 0.0
C2 (mean (SD)) 1.000 0.0
Stratified by E:C1
Overall 1:0 2:0 3:0
n 450.01 100.01 100.00 100.00
E (mean (SD)) 2.00 (0.82) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00)
C (mean (SD)) 2.13 (0.88) 1.60 (0.49) 1.60 (0.49) 1.60 (0.49)
Y = 1 (%) 177.0 (39.4) 22.0 (22.1) 22.0 (22.0) 22.0 (22.0)
C1 = 1 (%) 150.0 (33.3) 0.0 ( 0.0) 0.0 ( 0.0) 0.0 ( 0.0)
C2 (mean (SD)) 0.47 (0.50) 0.60 (0.49) 0.60 (0.49) 0.60 (0.49)
Stratified by E:C1
1:1 2:1 3:1 p test
n 50.00 50.00 50.00
E (mean (SD)) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00) <0.001
C (mean (SD)) 3.20 (0.40) 3.20 (0.40) 3.20 (0.40) <0.001
Y = 1 (%) 37.0 ( 74.0) 37.0 ( 74.0) 37.0 ( 74.0) <0.001
C1 = 1 (%) 50.0 (100.0) 50.0 (100.0) 50.0 (100.0) <0.001
C2 (mean (SD)) 0.20 (0.40) 0.20 (0.40) 0.20 (0.40) <0.001
Stratified by E:C1
Missing
n
E (mean (SD)) 0.0
C (mean (SD)) 0.0
Y = 1 (%) 0.2
C1 = 1 (%) 0.0
C2 (mean (SD)) 0.0
Stratified by E
1 2 3 p test
n 150.01 150.00 150.00
E (mean (SD)) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00) <0.001
C (mean (SD)) 2.13 (0.89) 2.13 (0.89) 2.13 (0.89) 1.000
Y = 1 (%) 59.0 (39.4) 59.0 (39.3) 59.0 (39.3) 1.000
C1 = 1 (%) 50.0 (33.3) 50.0 (33.3) 50.0 (33.3) 1.000
C2 (mean (SD)) 0.47 (0.50) 0.47 (0.50) 0.47 (0.50) 1.000
Stratified by E
1 2 3 p test
n 150.01 150.00 150.00
E (mean (SD)) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00) <0.001
C (mean (SD)) 2.13 (0.89) 2.13 (0.89) 2.13 (0.89) 1.000
Y = 1 (%) 59.0 (39.4) 59.0 (39.3) 59.0 (39.3) 1.000
C1 = 1 (%) 50.0 (33.3) 50.0 (33.3) 50.0 (33.3) 1.000
C2 (mean (SD)) 0.47 (0.50) 0.47 (0.50) 0.47 (0.50) 1.000
Overall
n 450.01
E (mean (SD)) 2.00 (0.82)
C (mean (SD)) 2.13 (0.88)
Y = 1 (%) 177.0 (39.4)
C1 = 1 (%) 150.0 (33.3)
C2 (mean (SD)) 0.47 (0.50)
Overall
n 450.01
E (mean (SD)) 2.00 (0.82)
C (mean (SD)) 2.13 (0.88)
Y = 1 (%) 177.0 (39.4)
C1 = 1 (%) 150.0 (33.3)
C2 (mean (SD)) 0.47 (0.50)
Overall
n 450.01
E (mean (SD)) 2.00 (0.82)
C (mean (SD)) 2.13 (0.88)
Y (%)
0 272.7 (60.6)
1 177.0 (39.3)
NA 0.3 ( 0.1)
C1 = 1 (%) 150.0 (33.3)
C2 (mean (SD)) 0.47 (0.50)
Overall
n 450.01
E (mean (SD)) 2.00 (0.82)
C (mean (SD)) 2.13 (0.88)
Y (%)
0 272.7 (60.6)
1 177.0 (39.3)
NA 0.3 ( 0.1)
C1 = 1 (%) 150.0 (33.3)
C2 (mean (SD)) 0.47 (0.50)
Stratified by E:C1
1:0 2:0 3:0 1:1
n 100.01 100.00 100.00 50.00
E (mean (SD)) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00) 1.00 (0.00)
C (mean (SD)) 1.60 (0.49) 1.60 (0.49) 1.60 (0.49) 3.20 (0.40)
Y = 1 (%) 22.0 (22.1) 22.0 (22.0) 22.0 (22.0) 37.0 ( 74.0)
C1 = 1 (%) 0.0 ( 0.0) 0.0 ( 0.0) 0.0 ( 0.0) 50.0 (100.0)
C2 (mean (SD)) 0.60 (0.49) 0.60 (0.49) 0.60 (0.49) 0.20 (0.40)
Stratified by E:C1
2:1 3:1 p test
n 50.00 50.00
E (mean (SD)) 2.00 (0.00) 3.00 (0.00) <0.001
C (mean (SD)) 3.20 (0.40) 3.20 (0.40) <0.001
Y = 1 (%) 37.0 ( 74.0) 37.0 ( 74.0) <0.001
C1 = 1 (%) 50.0 (100.0) 50.0 (100.0) <0.001
C2 (mean (SD)) 0.20 (0.40) 0.20 (0.40) <0.001
Stratified by E:C1
1:0 2:0 3:0 1:1
n 100.01 100.00 100.00 50.00
E (mean (SD)) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00) 1.00 (0.00)
C (mean (SD)) 1.60 (0.49) 1.60 (0.49) 1.60 (0.49) 3.20 (0.40)
Y = 1 (%) 22.0 (22.1) 22.0 (22.0) 22.0 (22.0) 37.0 ( 74.0)
C1 = 1 (%) 0.0 ( 0.0) 0.0 ( 0.0) 0.0 ( 0.0) 50.0 (100.0)
C2 (mean (SD)) 0.60 (0.49) 0.60 (0.49) 0.60 (0.49) 0.20 (0.40)
Stratified by E:C1
2:1 3:1 p test
n 50.00 50.00
E (mean (SD)) 2.00 (0.00) 3.00 (0.00) <0.001
C (mean (SD)) 3.20 (0.40) 3.20 (0.40) <0.001
Y = 1 (%) 37.0 ( 74.0) 37.0 ( 74.0) <0.001
C1 = 1 (%) 50.0 (100.0) 50.0 (100.0) <0.001
C2 (mean (SD)) 0.20 (0.40) 0.20 (0.40) <0.001
Stratified by E
1 2 3
n 150.0120 150.0030 150.0000
E (mean (SD)) 1.0000 (0.0000) 2.0000 (0.0000) 3.0000 (0.0000)
C (mean (SD)) 2.1332 (0.8854) 2.1333 (0.8861) 2.1333 (0.8861)
Y = 1 (%) 59.001 (39.406) 59.001 (39.333) 59.000 (39.333)
C1 = 1 (%) 50.000 (33.331) 50.000 (33.333) 50.000 (33.333)
C2 (mean (SD)) 0.4666 (0.4994) 0.4667 (0.4999) 0.4667 (0.4998)
Stratified by E
p test
n
E (mean (SD)) <0.00001
C (mean (SD)) 1.00000
Y = 1 (%) 0.99982
C1 = 1 (%) 1.00000
C2 (mean (SD)) 1.00000
Stratified by E
1 2 3
n 150.0120 150.0030 150.0000
E (mean (SD)) 1.0000 (0.0000) 2.0000 (0.0000) 3.0000 (0.0000)
C (mean (SD)) 2.1332 (0.8854) 2.1333 (0.8861) 2.1333 (0.8861)
Y = 1 (%) 59.001 (39.406) 59.001 (39.333) 59.000 (39.333)
C1 = 1 (%) 50.000 (33.331) 50.000 (33.333) 50.000 (33.333)
C2 (mean (SD)) 0.4666 (0.4994) 0.4667 (0.4999) 0.4667 (0.4998)
Stratified by E
p test
n
E (mean (SD)) <0.00001
C (mean (SD)) 1.00000
Y = 1 (%) 0.99982
C1 = 1 (%) 1.00000
C2 (mean (SD)) 1.00000
Stratified by E
1 2 3
n 150.01 150.00 150.00
E (mean (SD)) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00)
C (mean (SD)) 2.13 (0.89) 2.13 (0.89) 2.13 (0.89)
Y = 1 (%) 59.0 (39.4) 59.0 (39.3) 59.0 (39.3)
C1 = 1 (%) 50.0 (33.3) 50.0 (33.3) 50.0 (33.3)
C2 (mean (SD)) 0.47 (0.50) 0.47 (0.50) 0.47 (0.50)
Stratified by E
1 2 3
n 150.01 150.00 150.00
E (mean (SD)) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00)
C (mean (SD)) 2.13 (0.89) 2.13 (0.89) 2.13 (0.89)
Y = 1 (%) 59.0 (39.4) 59.0 (39.3) 59.0 (39.3)
C1 = 1 (%) 50.0 (33.3) 50.0 (33.3) 50.0 (33.3)
C2 (mean (SD)) 0.47 (0.50) 0.47 (0.50) 0.47 (0.50)
Stratified by E
1 2 3
n 150.01 150.00 150.00
E (mean (SD)) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00)
C (median [IQR]) 2.00 [1.00, 3.00] 2.00 [1.00, 3.00] 2.00 [1.00, 3.00]
Y = 1 (%) 59.0 (39.4) 59.0 (39.3) 59.0 (39.3)
C1 = 1 (%) 50.0 (33.3) 50.0 (33.3) 50.0 (33.3)
C2 (mean (SD)) 0.47 (0.50) 0.47 (0.50) 0.47 (0.50)
Stratified by E
p test
n
E (mean (SD)) <0.001
C (median [IQR]) 1.000 nonnorm
Y = 1 (%) NA exact
C1 = 1 (%) 1.000
C2 (mean (SD)) 1.000
Stratified by E
1 2 3
n 150.01 150.00 150.00
E (mean (SD)) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00)
C (median [IQR]) 2.00 [1.00, 3.00] 2.00 [1.00, 3.00] 2.00 [1.00, 3.00]
Y = 1 (%) 59.0 (39.4) 59.0 (39.3) 59.0 (39.3)
C1 = 1 (%) 50.0 (33.3) 50.0 (33.3) 50.0 (33.3)
C2 (mean (SD)) 0.47 (0.50) 0.47 (0.50) 0.47 (0.50)
Stratified by E
p test
n
E (mean (SD)) <0.001
C (median [IQR]) 1.000 nonnorm
Y = 1 (%) NA exact
C1 = 1 (%) 1.000
C2 (mean (SD)) 1.000
Stratified by E
1 2
n 150.01 150.00
E (mean (SD)) 1.00 (0.00) 2.00 (0.00)
C (median [range]) 2.00 [1.00, 4.00] 2.00 [1.00, 4.00]
Y = 1 (%) 59.0 (39.4) 59.0 (39.3)
C1 = 1 (%) 50.0 (33.3) 50.0 (33.3)
C2 (mean (SD)) 0.47 (0.50) 0.47 (0.50)
Stratified by E
3 p test
n 150.00
E (mean (SD)) 3.00 (0.00) <0.001
C (median [range]) 2.00 [1.00, 4.00] 1.000 nonnorm
Y = 1 (%) 59.0 (39.3) 1.000
C1 = 1 (%) 50.0 (33.3) 1.000
C2 (mean (SD)) 0.47 (0.50) 1.000
Stratified by E
1 2
n 150.01 150.00
E (mean (SD)) 1.00 (0.00) 2.00 (0.00)
C (median [range]) 2.00 [1.00, 4.00] 2.00 [1.00, 4.00]
Y = 1 (%) 59.0 (39.4) 59.0 (39.3)
C1 = 1 (%) 50.0 (33.3) 50.0 (33.3)
C2 (mean (SD)) 0.47 (0.50) 0.47 (0.50)
Stratified by E
3 p test
n 150.00
E (mean (SD)) 3.00 (0.00) <0.001
C (median [range]) 2.00 [1.00, 4.00] 1.000 nonnorm
Y = 1 (%) 59.0 (39.3) 1.000
C1 = 1 (%) 50.0 (33.3) 1.000
C2 (mean (SD)) 0.47 (0.50) 1.000
Stratified by E
1 2 3 p test
n 150.01 150.00 150.00
E (mean (SD)) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00) <0.001
C (mean (SD)) 2.13 (0.89) 2.13 (0.89) 2.13 (0.89) 1.000
Y = 1 (%) 59.001 (39.406) 59.001 (39.333) 59.000 (39.333) 1.000
C1 = 1 (%) 50.000 (33.331) 50.000 (33.333) 50.000 (33.333) 1.000
C2 (mean (SD)) 0.47 (0.50) 0.47 (0.50) 0.47 (0.50) 1.000
Stratified by E
1 2 3 p test
n 150.01 150.00 150.00
E (mean (SD)) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00) <0.001
C (mean (SD)) 2.13 (0.89) 2.13 (0.89) 2.13 (0.89) 1.000
Y = 1 (%) 59.001 (39.406) 59.001 (39.333) 59.000 (39.333) 1.000
C1 = 1 (%) 50.000 (33.331) 50.000 (33.333) 50.000 (33.333) 1.000
C2 (mean (SD)) 0.47 (0.50) 0.47 (0.50) 0.47 (0.50) 1.000
Stratified by E
level 1 2
n 150.01 150.00
E (mean (SD)) 1.00 (0.00) 2.00 (0.00)
C (median [IQR]) 2.00 [1.00, 3.00] 2.00 [1.00, 3.00]
Y (%) 0 90.7 (60.6) 91.0 (60.7)
1 59.0 (39.4) 59.0 (39.3)
C1 (%) 0 100.0 (66.7) 100.0 (66.7)
1 50.0 (33.3) 50.0 (33.3)
C2 (mean (SD)) 0.47 (0.50) 0.47 (0.50)
Stratified by E
3 p test
n 150.00
E (mean (SD)) 3.00 (0.00) <0.001
C (median [IQR]) 2.00 [1.00, 3.00] 1.000 nonnorm
Y (%) 91.0 (60.7) NA exact
59.0 (39.3)
C1 (%) 100.0 (66.7) 1.000
50.0 (33.3)
C2 (mean (SD)) 0.47 (0.50) 1.000
Stratified by E
level 1 2
n 150.01 150.00
E (mean (SD)) 1.00 (0.00) 2.00 (0.00)
C (median [IQR]) 2.00 [1.00, 3.00] 2.00 [1.00, 3.00]
Y (%) 0 90.7 (60.6) 91.0 (60.7)
1 59.0 (39.4) 59.0 (39.3)
C1 (%) 0 100.0 (66.7) 100.0 (66.7)
1 50.0 (33.3) 50.0 (33.3)
C2 (mean (SD)) 0.47 (0.50) 0.47 (0.50)
Stratified by E
3 p test
n 150.00
E (mean (SD)) 3.00 (0.00) <0.001
C (median [IQR]) 2.00 [1.00, 3.00] 1.000 nonnorm
Y (%) 91.0 (60.7) NA exact
59.0 (39.3)
C1 (%) 100.0 (66.7) 1.000
50.0 (33.3)
C2 (mean (SD)) 0.47 (0.50) 1.000
"Stratified by E"
"" "1" "2"
"n" "150.01" "150.00"
"E (mean (SD))" "1.00 (0.00)" "2.00 (0.00)"
"C (median [IQR])" "2.00 [1.00, 3.00]" "2.00 [1.00, 3.00]"
"Y = 1 (%)" "59.001 (39.406)" "59.001 (39.333)"
"C1 = 1 (%)" "50.000 (33.331)" "50.000 (33.333)"
"C2 (mean (SD))" "0.47 (0.50)" "0.47 (0.50)"
"Stratified by E"
"" "3" "p" "test"
"n" "150.00" "" ""
"E (mean (SD))" "3.00 (0.00)" "<0.001" ""
"C (median [IQR])" "2.00 [1.00, 3.00]" "1.000" "nonnorm"
"Y = 1 (%)" "59.000 (39.333)" "NA" "exact"
"C1 = 1 (%)" "50.000 (33.333)" "1.000" ""
"C2 (mean (SD))" "0.47 (0.50)" "1.000" ""
"Stratified by E"
"" "1" "2"
"n" "150.01" "150.00"
"E (mean (SD))" "1.00 (0.00)" "2.00 (0.00)"
"C (median [IQR])" "2.00 [1.00, 3.00]" "2.00 [1.00, 3.00]"
"Y = 1 (%)" "59.001 (39.406)" "59.001 (39.333)"
"C1 = 1 (%)" "50.000 (33.331)" "50.000 (33.333)"
"C2 (mean (SD))" "0.47 (0.50)" "0.47 (0.50)"
"Stratified by E"
"" "3" "p" "test"
"n" "150.00" "" ""
"E (mean (SD))" "3.00 (0.00)" "<0.001" ""
"C (median [IQR])" "2.00 [1.00, 3.00]" "1.000" "nonnorm"
"Y = 1 (%)" "59.000 (39.333)" "NA" "exact"
"C1 = 1 (%)" "50.000 (33.333)" "1.000" ""
"C2 (mean (SD))" "0.47 (0.50)" "1.000" ""
Stratified by E:C1
1:0 2:0 3:0 1:1
n 100.01 100.00 100.00 50.00
E (mean (SD)) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00) 1.00 (0.00)
C (mean (SD)) 1.60 (0.49) 1.60 (0.49) 1.60 (0.49) 3.20 (0.40)
Stratified by E:C1
2:1 3:1 p test
n 50.00 50.00
E (mean (SD)) 2.00 (0.00) 3.00 (0.00) <0.001
C (mean (SD)) 3.20 (0.40) 3.20 (0.40) <0.001
Stratified by E:C1
1:0 2:0 3:0 1:1
n 100.01 100.00 100.00 50.00
E (mean (SD)) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00) 1.00 (0.00)
C (mean (SD)) 1.60 (0.49) 1.60 (0.49) 1.60 (0.49) 3.20 (0.40)
Stratified by E:C1
2:1 3:1 p test
n 50.00 50.00
E (mean (SD)) 2.00 (0.00) 3.00 (0.00) <0.001
C (mean (SD)) 3.20 (0.40) 3.20 (0.40) <0.001
Stratified by E:C1
1:0 2:0 3:0 1:1
n 100.0 100.0 100.0 50.0
Y = 1 (%) 22.0 (22.1) 22.0 (22.0) 22.0 (22.0) 37.0 ( 74.0)
C1 = 1 (%) 0.0 ( 0.0) 0.0 ( 0.0) 0.0 ( 0.0) 50.0 (100.0)
Stratified by E:C1
2:1 3:1 p test
n 50.0 50.0
Y = 1 (%) 37.0 ( 74.0) 37.0 ( 74.0) <0.001
C1 = 1 (%) 50.0 (100.0) 50.0 (100.0) <0.001
Stratified by E:C1
1:0 2:0 3:0 1:1
n 100.0 100.0 100.0 50.0
Y = 1 (%) 22.0 (22.1) 22.0 (22.0) 22.0 (22.0) 37.0 ( 74.0)
C1 = 1 (%) 0.0 ( 0.0) 0.0 ( 0.0) 0.0 ( 0.0) 50.0 (100.0)
Stratified by E:C1
2:1 3:1 p test
n 50.0 50.0
Y = 1 (%) 37.0 ( 74.0) 37.0 ( 74.0) <0.001
C1 = 1 (%) 50.0 (100.0) 50.0 (100.0) <0.001
Stratified by E
Overall 1 2 3
n 450.01 150.01 150.00 150.00
E (mean (SD)) 2.00 (0.82) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00)
C (mean (SD)) 2.13 (0.88) 2.13 (0.89) 2.13 (0.89) 2.13 (0.89)
Y = 1 (%) 177.0 (39.4) 59.0 (39.4) 59.0 (39.3) 59.0 (39.3)
C1 = 1 (%) 150.0 (33.3) 50.0 (33.3) 50.0 (33.3) 50.0 (33.3)
C2 (mean (SD)) 0.47 (0.50) 0.47 (0.50) 0.47 (0.50) 0.47 (0.50)
Stratified by E
p test SMD
n
E (mean (SD)) <0.001 Inf
C (mean (SD)) 1.000 <0.001
Y = 1 (%) 1.000 0.001
C1 = 1 (%) 1.000 <0.001
C2 (mean (SD)) 1.000 <0.001
Stratified by E
Overall 1 2 3
n 450.01 150.01 150.00 150.00
E (mean (SD)) 2.00 (0.82) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00)
C (mean (SD)) 2.13 (0.88) 2.13 (0.89) 2.13 (0.89) 2.13 (0.89)
Y = 1 (%) 177.0 (39.4) 59.0 (39.4) 59.0 (39.3) 59.0 (39.3)
C1 = 1 (%) 150.0 (33.3) 50.0 (33.3) 50.0 (33.3) 50.0 (33.3)
C2 (mean (SD)) 0.47 (0.50) 0.47 (0.50) 0.47 (0.50) 0.47 (0.50)
Stratified by E
p test SMD
n
E (mean (SD)) <0.001 Inf
C (mean (SD)) 1.000 <0.001
Y = 1 (%) 1.000 0.001
C1 = 1 (%) 1.000 <0.001
C2 (mean (SD)) 1.000 <0.001
Stratified by E:C1
Overall 1:0 2:0 3:0
n 450.01 100.01 100.00 100.00
E (mean (SD)) 2.00 (0.82) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00)
C (mean (SD)) 2.13 (0.88) 1.60 (0.49) 1.60 (0.49) 1.60 (0.49)
Y = 1 (%) 177.0 (39.4) 22.0 (22.1) 22.0 (22.0) 22.0 (22.0)
C1 = 1 (%) 150.0 (33.3) 0.0 ( 0.0) 0.0 ( 0.0) 0.0 ( 0.0)
C2 (mean (SD)) 0.47 (0.50) 0.60 (0.49) 0.60 (0.49) 0.60 (0.49)
Stratified by E:C1
1:1 2:1 3:1 p test
n 50.00 50.00 50.00
E (mean (SD)) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00) <0.001
C (mean (SD)) 3.20 (0.40) 3.20 (0.40) 3.20 (0.40) <0.001
Y = 1 (%) 37.0 ( 74.0) 37.0 ( 74.0) 37.0 ( 74.0) <0.001
C1 = 1 (%) 50.0 (100.0) 50.0 (100.0) 50.0 (100.0) <0.001
C2 (mean (SD)) 0.20 (0.40) 0.20 (0.40) 0.20 (0.40) <0.001
Stratified by E:C1
SMD
n
E (mean (SD)) Inf
C (mean (SD)) 2.137
Y = 1 (%) 0.731
C1 = 1 (%) NaN
C2 (mean (SD)) 0.534
Stratified by E:C1
Overall 1:0 2:0 3:0
n 450.01 100.01 100.00 100.00
E (mean (SD)) 2.00 (0.82) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00)
C (mean (SD)) 2.13 (0.88) 1.60 (0.49) 1.60 (0.49) 1.60 (0.49)
Y = 1 (%) 177.0 (39.4) 22.0 (22.1) 22.0 (22.0) 22.0 (22.0)
C1 = 1 (%) 150.0 (33.3) 0.0 ( 0.0) 0.0 ( 0.0) 0.0 ( 0.0)
C2 (mean (SD)) 0.47 (0.50) 0.60 (0.49) 0.60 (0.49) 0.60 (0.49)
Stratified by E:C1
1:1 2:1 3:1 p test
n 50.00 50.00 50.00
E (mean (SD)) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00) <0.001
C (mean (SD)) 3.20 (0.40) 3.20 (0.40) 3.20 (0.40) <0.001
Y = 1 (%) 37.0 ( 74.0) 37.0 ( 74.0) 37.0 ( 74.0) <0.001
C1 = 1 (%) 50.0 (100.0) 50.0 (100.0) 50.0 (100.0) <0.001
C2 (mean (SD)) 0.20 (0.40) 0.20 (0.40) 0.20 (0.40) <0.001
Stratified by E:C1
SMD
n
E (mean (SD)) Inf
C (mean (SD)) 2.137
Y = 1 (%) 0.731
C1 = 1 (%) NaN
C2 (mean (SD)) 0.534
Stratified by E
Overall 1 2
n 4,50D01 1,50D01 1,50D00
E (mean (SD)) 2D00 (0D82) 1D00 (0D00) 2D00 (0D00)
C (mean (SD)) 2D13 (0D88) 2D13 (0D89) 2D13 (0D89)
Y = 1 (%) 1,77D0 (39D4) 59D0 (39D4) 59D0 (39D3)
C1 = 1 (%) 1,50D0 (33D3) 50D0 (33D3) 50D0 (33D3)
C2 (mean (SD)) 0D47 (0D50) 0D47 (0D50) 0D47 (0D50)
Stratified by E
3 p test SMD
n 1,50D00
E (mean (SD)) 3D00 (0D00) <0D001 Inf
C (mean (SD)) 2D13 (0D89) 1D000 <0D001
Y = 1 (%) 59D0 (39D3) 1D000 0D001
C1 = 1 (%) 50D0 (33D3) 1D000 <0D001
C2 (mean (SD)) 0D47 (0D50) 1D000 <0D001
Stratified by E
Overall 1 2
n 4,50D01 1,50D01 1,50D00
E (mean (SD)) 2D00 (0D82) 1D00 (0D00) 2D00 (0D00)
C (mean (SD)) 2D13 (0D88) 2D13 (0D89) 2D13 (0D89)
Y = 1 (%) 1,77D0 (39D4) 59D0 (39D4) 59D0 (39D3)
C1 = 1 (%) 1,50D0 (33D3) 50D0 (33D3) 50D0 (33D3)
C2 (mean (SD)) 0D47 (0D50) 0D47 (0D50) 0D47 (0D50)
Stratified by E
3 p test SMD
n 1,50D00
E (mean (SD)) 3D00 (0D00) <0D001 Inf
C (mean (SD)) 2D13 (0D89) 1D000 <0D001
Y = 1 (%) 59D0 (39D3) 1D000 0D001
C1 = 1 (%) 50D0 (33D3) 1D000 <0D001
C2 (mean (SD)) 0D47 (0D50) 1D000 <0D001
Stratified by E:C1
Overall 1:0 2:0
n 4,50D01 1,00D01 1,00D00
E (mean (SD)) 2D00 (0D82) 1D00 (0D00) 2D00 (0D00)
C (mean (SD)) 2D13 (0D88) 1D60 (0D49) 1D60 (0D49)
Y = 1 (%) 1,77D0 (39D4) 22D0 (22D1) 22D0 (22D0)
C1 = 1 (%) 1,50D0 (33D3) 0D0 ( 0D0) 0D0 ( 0D0)
C2 (mean (SD)) 0D47 (0D50) 0D60 (0D49) 0D60 (0D49)
Stratified by E:C1
3:0 1:1 2:1
n 1,00D00 50D00 50D00
E (mean (SD)) 3D00 (0D00) 1D00 (0D00) 2D00 (0D00)
C (mean (SD)) 1D60 (0D49) 3D20 (0D40) 3D20 (0D40)
Y = 1 (%) 22D0 (22D0) 37D0 ( 74D0) 37D0 ( 74D0)
C1 = 1 (%) 0D0 ( 0D0) 50D0 (1,00D0) 50D0 (1,00D0)
C2 (mean (SD)) 0D60 (0D49) 0D20 (0D40) 0D20 (0D40)
Stratified by E:C1
3:1 p test SMD
n 50D00
E (mean (SD)) 3D00 (0D00) <0D001 Inf
C (mean (SD)) 3D20 (0D40) <0D001 2D137
Y = 1 (%) 37D0 ( 74D0) <0D001 0D731
C1 = 1 (%) 50D0 (1,00D0) <0D001 NaN
C2 (mean (SD)) 0D20 (0D40) <0D001 0D534
Stratified by E:C1
Overall 1:0 2:0
n 4,50D01 1,00D01 1,00D00
E (mean (SD)) 2D00 (0D82) 1D00 (0D00) 2D00 (0D00)
C (mean (SD)) 2D13 (0D88) 1D60 (0D49) 1D60 (0D49)
Y = 1 (%) 1,77D0 (39D4) 22D0 (22D1) 22D0 (22D0)
C1 = 1 (%) 1,50D0 (33D3) 0D0 ( 0D0) 0D0 ( 0D0)
C2 (mean (SD)) 0D47 (0D50) 0D60 (0D49) 0D60 (0D49)
Stratified by E:C1
3:0 1:1 2:1
n 1,00D00 50D00 50D00
E (mean (SD)) 3D00 (0D00) 1D00 (0D00) 2D00 (0D00)
C (mean (SD)) 1D60 (0D49) 3D20 (0D40) 3D20 (0D40)
Y = 1 (%) 22D0 (22D0) 37D0 ( 74D0) 37D0 ( 74D0)
C1 = 1 (%) 0D0 ( 0D0) 50D0 (1,00D0) 50D0 (1,00D0)
C2 (mean (SD)) 0D60 (0D49) 0D20 (0D40) 0D20 (0D40)
Stratified by E:C1
3:1 p test SMD
n 50D00
E (mean (SD)) 3D00 (0D00) <0D001 Inf
C (mean (SD)) 3D20 (0D40) <0D001 2D137
Y = 1 (%) 37D0 ( 74D0) <0D001 0D731
C1 = 1 (%) 50D0 (1,00D0) <0D001 NaN
C2 (mean (SD)) 0D20 (0D40) <0D001 0D534
Stratified by E
1 2 3 p test
n 150.0 150.0 150.0
Y = 1 (%) 59.0 (39.4) 59.0 (39.3) 59.0 (39.3) 1.000
C1 = 1 (%) 50.0 (33.3) 50.0 (33.3) 50.0 (33.3) 1.000
Stratified by E
1 2 3 p test
n 150.0 150.0 150.0
Y = 1 (%) 59.0 (39.4) 59.0 (39.3) 59.0 (39.3) 1.000
C1 = 1 (%) 50.0 (33.3) 50.0 (33.3) 50.0 (33.3) 1.000
Stratified by
Overall
n 450.0
Y = 1 (%) 177.0 (39.4)
C1 = 1 (%) 150.0 (33.3)
Stratified by
Overall
n 450.0
Y = 1 (%) 177.0 (39.4)
C1 = 1 (%) 150.0 (33.3)
Stratified by
Overall
n 450.0
Y (%)
0 272.7 (60.6)
1 177.0 (39.3)
NA 0.3 ( 0.1)
C1 = 1 (%) 150.0 (33.3)
Stratified by
Overall
n 450.0
Y (%)
0 272.7 (60.6)
1 177.0 (39.3)
NA 0.3 ( 0.1)
C1 = 1 (%) 150.0 (33.3)
Stratified by E:C1
1:0 2:0 3:0 1:1 2:1
n 100.0 100.0 100.0 50.0 50.0
Y = 1 (%) 22.0 (22.1) 22.0 (22.0) 22.0 (22.0) 37.0 ( 74.0) 37.0 ( 74.0)
C1 = 1 (%) 0.0 ( 0.0) 0.0 ( 0.0) 0.0 ( 0.0) 50.0 (100.0) 50.0 (100.0)
Stratified by E:C1
3:1 p test
n 50.0
Y = 1 (%) 37.0 ( 74.0) <0.001
C1 = 1 (%) 50.0 (100.0) <0.001
Stratified by E:C1
1:0 2:0 3:0 1:1 2:1
n 100.0 100.0 100.0 50.0 50.0
Y = 1 (%) 22.0 (22.1) 22.0 (22.0) 22.0 (22.0) 37.0 ( 74.0) 37.0 ( 74.0)
C1 = 1 (%) 0.0 ( 0.0) 0.0 ( 0.0) 0.0 ( 0.0) 50.0 (100.0) 50.0 (100.0)
Stratified by E:C1
3:1 p test
n 50.0
Y = 1 (%) 37.0 ( 74.0) <0.001
C1 = 1 (%) 50.0 (100.0) <0.001
Stratified by E:C1
1:0 2:0 3:0
n 100.012 100.003 100.000
Y = 1 (%) 22.001 (22.062) 22.001 (22.000) 22.000 (22.000)
C1 = 1 (%) 0.000 ( 0.000) 0.000 ( 0.000) 0.000 ( 0.000)
Stratified by E:C1
1:1 2:1 3:1 p
n 50.000 50.000 50.000
Y = 1 (%) 37.000 ( 74.000) 37.000 ( 74.000) 37.000 ( 74.000) <0.00001
C1 = 1 (%) 50.000 (100.000) 50.000 (100.000) 50.000 (100.000) <0.00001
Stratified by E:C1
test
n
Y = 1 (%)
C1 = 1 (%)
Stratified by E:C1
1:0 2:0 3:0
n 100.012 100.003 100.000
Y = 1 (%) 22.001 (22.062) 22.001 (22.000) 22.000 (22.000)
C1 = 1 (%) 0.000 ( 0.000) 0.000 ( 0.000) 0.000 ( 0.000)
Stratified by E:C1
1:1 2:1 3:1 p
n 50.000 50.000 50.000
Y = 1 (%) 37.000 ( 74.000) 37.000 ( 74.000) 37.000 ( 74.000) <0.00001
C1 = 1 (%) 50.000 (100.000) 50.000 (100.000) 50.000 (100.000) <0.00001
Stratified by E:C1
test
n
Y = 1 (%)
C1 = 1 (%)
Stratified by E:C1
1:0 2:0 3:0 1:1 2:1
n 100.0 100.0 100.0 50.0 50.0
Y = 1 (%) 22.0 (22.1) 22.0 (22.0) 22.0 (22.0) 37.0 ( 74.0) 37.0 ( 74.0)
C1 = 1 (%) 0.0 ( 0.0) 0.0 ( 0.0) 0.0 ( 0.0) 50.0 (100.0) 50.0 (100.0)
Stratified by E:C1
3:1
n 50.0
Y = 1 (%) 37.0 ( 74.0)
C1 = 1 (%) 50.0 (100.0)
Stratified by E:C1
1:0 2:0 3:0 1:1 2:1
n 100.0 100.0 100.0 50.0 50.0
Y = 1 (%) 22.0 (22.1) 22.0 (22.0) 22.0 (22.0) 37.0 ( 74.0) 37.0 ( 74.0)
C1 = 1 (%) 0.0 ( 0.0) 0.0 ( 0.0) 0.0 ( 0.0) 50.0 (100.0) 50.0 (100.0)
Stratified by E:C1
3:1
n 50.0
Y = 1 (%) 37.0 ( 74.0)
C1 = 1 (%) 50.0 (100.0)
Stratified by E
1 2 3 p test
n 150.012 150.003 150.000
Y = 1 (%) 59.001 (39.406) 59.001 (39.333) 59.000 (39.333) 1.000
C1 = 1 (%) 50.000 (33.331) 50.000 (33.333) 50.000 (33.333) 1.000
Stratified by E
1 2 3 p test
n 150.012 150.003 150.000
Y = 1 (%) 59.001 (39.406) 59.001 (39.333) 59.000 (39.333) 1.000
C1 = 1 (%) 50.000 (33.331) 50.000 (33.333) 50.000 (33.333) 1.000
Stratified by E
level 1 2 3 p test
n 150.0 150.0 150.0
Y (%) 0 90.7 (60.6) 91.0 (60.7) 91.0 (60.7) 1.000
1 59.0 (39.4) 59.0 (39.3) 59.0 (39.3)
C1 (%) 0 100.0 (66.7) 100.0 (66.7) 100.0 (66.7) 1.000
1 50.0 (33.3) 50.0 (33.3) 50.0 (33.3)
Stratified by E
level 1 2 3 p test
n 150.0 150.0 150.0
Y (%) 0 90.7 (60.6) 91.0 (60.7) 91.0 (60.7) 1.000
1 59.0 (39.4) 59.0 (39.3) 59.0 (39.3)
C1 (%) 0 100.0 (66.7) 100.0 (66.7) 100.0 (66.7) 1.000
1 50.0 (33.3) 50.0 (33.3) 50.0 (33.3)
Stratified by E
1 2 3 p test
n 150.0 150.0 150.0
Y = 1 59.0 (39.4) 59.0 (39.3) 59.0 (39.3) 1.000
C1 = 1 50.0 (33.3) 50.0 (33.3) 50.0 (33.3) 1.000
Stratified by E
1 2 3 p test
n 150.0 150.0 150.0
Y = 1 59.0 (39.4) 59.0 (39.3) 59.0 (39.3) 1.000
C1 = 1 50.0 (33.3) 50.0 (33.3) 50.0 (33.3) 1.000
Stratified by E
1 2 3 p test
n 150.0 150.0 150.0
Y = 1 59.0 59.0 59.0 1.000
C1 = 1 50.0 50.0 50.0 1.000
Stratified by E
1 2 3 p test
n 150.0 150.0 150.0
Y = 1 59.0 59.0 59.0 1.000
C1 = 1 50.0 50.0 50.0 1.000
Stratified by E
1 2 3 p test
n 150.0 150.0 150.0
Y = 1 (%) 39.4 39.3 39.3 1.000
C1 = 1 (%) 33.3 33.3 33.3 1.000
Stratified by E
1 2 3 p test
n 150.0 150.0 150.0
Y = 1 (%) 39.4 39.3 39.3 1.000
C1 = 1 (%) 33.3 33.3 33.3 1.000
Stratified by E
1 2 3 p test
n 150.0 150.0 150.0
Y = 1 % (freq) 39.4 (59.0) 39.3 (59.0) 39.3 (59.0) 1.000
C1 = 1 % (freq) 33.3 (50.0) 33.3 (50.0) 33.3 (50.0) 1.000
Stratified by E
1 2 3 p test
n 150.0 150.0 150.0
Y = 1 % (freq) 39.4 (59.0) 39.3 (59.0) 39.3 (59.0) 1.000
C1 = 1 % (freq) 33.3 (50.0) 33.3 (50.0) 33.3 (50.0) 1.000
Stratified by E
1 2
n 150.0 150.0
Y = 0/1 (%) 90.7/59.0 (60.6/39.4) 91.0/59.0 (60.7/39.3)
C1 = 1 (%) 50.0 (33.3) 50.0 (33.3)
Stratified by E
3 p test
n 150.0
Y = 0/1 (%) 91.0/59.0 (60.7/39.3) 1.000
C1 = 1 (%) 50.0 (33.3) 1.000
Stratified by E
1 2
n 150.0 150.0
Y = 0/1 (%) 90.7/59.0 (60.6/39.4) 91.0/59.0 (60.7/39.3)
C1 = 1 (%) 50.0 (33.3) 50.0 (33.3)
Stratified by E
3 p test
n 150.0
Y = 0/1 (%) 91.0/59.0 (60.7/39.3) 1.000
C1 = 1 (%) 50.0 (33.3) 1.000
"Stratified by E"
"" "level" "1" "2" "3" "p" "test"
"n" "" "150.0" "150.0" "150.0" "" ""
"Y (%)" "0" "90.7 (60.6)" "91.0 (60.7)" "91.0 (60.7)" "1.000" ""
"" "1" "59.0 (39.4)" "59.0 (39.3)" "59.0 (39.3)" "" ""
"C1 (%)" "0" "100.0 (66.7)" "100.0 (66.7)" "100.0 (66.7)" "1.000" ""
"" "1" "50.0 (33.3)" "50.0 (33.3)" "50.0 (33.3)" "" ""
"Stratified by E"
"" "level" "1" "2" "3" "p" "test"
"n" "" "150.0" "150.0" "150.0" "" ""
"Y (%)" "0" "90.7 (60.6)" "91.0 (60.7)" "91.0 (60.7)" "1.000" ""
"" "1" "59.0 (39.4)" "59.0 (39.3)" "59.0 (39.3)" "" ""
"C1 (%)" "0" "100.0 (66.7)" "100.0 (66.7)" "100.0 (66.7)" "1.000" ""
"" "1" "50.0 (33.3)" "50.0 (33.3)" "50.0 (33.3)" "" ""
Stratified by E
Overall 1 2 3 p test
n 450.0 150.0 150.0 150.0
Y = 1 (%) 177.0 (39.4) 59.0 (39.4) 59.0 (39.3) 59.0 (39.3) 1.000
C1 = 1 (%) 150.0 (33.3) 50.0 (33.3) 50.0 (33.3) 50.0 (33.3) 1.000
Stratified by E
SMD
n
Y = 1 (%) 0.001
C1 = 1 (%) <0.001
Stratified by E
Overall 1 2 3 p test
n 450.0 150.0 150.0 150.0
Y = 1 (%) 177.0 (39.4) 59.0 (39.4) 59.0 (39.3) 59.0 (39.3) 1.000
C1 = 1 (%) 150.0 (33.3) 50.0 (33.3) 50.0 (33.3) 50.0 (33.3) 1.000
Stratified by E
SMD
n
Y = 1 (%) 0.001
C1 = 1 (%) <0.001
Stratified by E:C1
Overall 1:0 2:0 3:0 1:1
n 450.0 100.0 100.0 100.0 50.0
Y = 1 (%) 177.0 (39.4) 22.0 (22.1) 22.0 (22.0) 22.0 (22.0) 37.0 ( 74.0)
C1 = 1 (%) 150.0 (33.3) 0.0 ( 0.0) 0.0 ( 0.0) 0.0 ( 0.0) 50.0 (100.0)
Stratified by E:C1
2:1 3:1 p test SMD
n 50.0 50.0
Y = 1 (%) 37.0 ( 74.0) 37.0 ( 74.0) <0.001 0.731
C1 = 1 (%) 50.0 (100.0) 50.0 (100.0) <0.001 NaN
Stratified by E:C1
Overall 1:0 2:0 3:0 1:1
n 450.0 100.0 100.0 100.0 50.0
Y = 1 (%) 177.0 (39.4) 22.0 (22.1) 22.0 (22.0) 22.0 (22.0) 37.0 ( 74.0)
C1 = 1 (%) 150.0 (33.3) 0.0 ( 0.0) 0.0 ( 0.0) 0.0 ( 0.0) 50.0 (100.0)
Stratified by E:C1
2:1 3:1 p test SMD
n 50.0 50.0
Y = 1 (%) 37.0 ( 74.0) 37.0 ( 74.0) <0.001 0.731
C1 = 1 (%) 50.0 (100.0) 50.0 (100.0) <0.001 NaN
Stratified by E:C1
1:0 2:0 3:0 1:1 2:1
n 100.0 100.0 100.0 50.0 50.0
Y = 1 (%) 22.0 (22.1) 22.0 (22.0) 22.0 (22.0) 37.0 ( 74.0) 37.0 ( 74.0)
C1 = 1 (%) 0.0 ( 0.0) 0.0 ( 0.0) 0.0 ( 0.0) 50.0 (100.0) 50.0 (100.0)
Stratified by E:C1
3:1 p test
n 50.0
Y = 1 (%) 37.0 ( 74.0) <0.001
C1 = 1 (%) 50.0 (100.0) <0.001
Cell Contents
|-------------------------|
| N |
| Chi-square contribution |
| N / Row Total |
| N / Col Total |
| N / Table Total |
|-------------------------|
Total Observations in Table: 449.7292
| E:C1
Y | 1:0 | 2:0 | 3:0 | 1:1 | 2:1 | 3:1 | Row Total |
-------------|-----------|-----------|-----------|-----------|-----------|-----------|-----------|
0 | 77 | 78 | 78 | 13 | 13 | 13 | 272 |
| 4.919 | 4.968 | 4.968 | 9.895 | 9.895 | 9.895 | |
| 0.285 | 0.286 | 0.286 | 0.048 | 0.048 | 0.048 | 0.606 |
| 0.779 | 0.780 | 0.780 | 0.260 | 0.260 | 0.260 | |
| 0.173 | 0.173 | 0.173 | 0.029 | 0.029 | 0.029 | |
-------------|-----------|-----------|-----------|-----------|-----------|-----------|-----------|
1 | 22 | 22 | 22 | 37 | 37 | 37 | 177 |
| 7.580 | 7.655 | 7.655 | 15.246 | 15.246 | 15.246 | |
| 0.124 | 0.124 | 0.124 | 0.209 | 0.209 | 0.209 | 0.394 |
| 0.221 | 0.220 | 0.220 | 0.740 | 0.740 | 0.740 | |
| 0.049 | 0.049 | 0.049 | 0.082 | 0.082 | 0.082 | |
-------------|-----------|-----------|-----------|-----------|-----------|-----------|-----------|
Column Total | 99 | 100 | 100 | 50 | 50 | 50 | 449 |
| 0.222 | 0.222 | 0.222 | 0.111 | 0.111 | 0.111 | |
-------------|-----------|-----------|-----------|-----------|-----------|-----------|-----------|
Cell Contents
|-------------------------|
| N |
| Chi-square contribution |
| N / Row Total |
| N / Col Total |
| N / Table Total |
|-------------------------|
Total Observations in Table: 450.015
| E:C1
C1 | 1:0 | 2:0 | 3:0 | 1:1 | 2:1 | 3:1 | Row Total |
-------------|-----------|-----------|-----------|-----------|-----------|-----------|-----------|
0 | 100 | 100 | 100 | 0 | 0 | 0 | 300 |
| 16.667 | 16.666 | 16.665 | 33.334 | 33.334 | 33.334 | |
| 0.333 | 0.333 | 0.333 | 0.000 | 0.000 | 0.000 | 0.667 |
| 1.000 | 1.000 | 1.000 | 0.000 | 0.000 | 0.000 | |
| 0.222 | 0.222 | 0.222 | 0.000 | 0.000 | 0.000 | |
-------------|-----------|-----------|-----------|-----------|-----------|-----------|-----------|
1 | 0 | 0 | 0 | 50 | 50 | 50 | 150 |
| 33.336 | 33.333 | 33.332 | 66.671 | 66.671 | 66.671 | |
| 0.000 | 0.000 | 0.000 | 0.333 | 0.333 | 0.333 | 0.333 |
| 0.000 | 0.000 | 0.000 | 1.000 | 1.000 | 1.000 | |
| 0.000 | 0.000 | 0.000 | 0.111 | 0.111 | 0.111 | |
-------------|-----------|-----------|-----------|-----------|-----------|-----------|-----------|
Column Total | 100 | 100 | 100 | 50 | 50 | 50 | 450 |
| 0.222 | 0.222 | 0.222 | 0.111 | 0.111 | 0.111 | |
-------------|-----------|-----------|-----------|-----------|-----------|-----------|-----------|
Stratified by E
1 2 3 p test
n 150.01 150.00 150.00
E (mean (SD)) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00) <0.001
C (mean (SD)) 2.13 (0.89) 2.13 (0.89) 2.13 (0.89) 1.000
C2 (mean (SD)) 0.47 (0.50) 0.47 (0.50) 0.47 (0.50) 1.000
Stratified by E
1 2 3 p test
n 150.01 150.00 150.00
E (mean (SD)) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00) <0.001
C (mean (SD)) 2.13 (0.89) 2.13 (0.89) 2.13 (0.89) 1.000
C2 (mean (SD)) 0.47 (0.50) 0.47 (0.50) 0.47 (0.50) 1.000
Stratified by
Overall
n 450.01
E (mean (SD)) 2.00 (0.82)
C (mean (SD)) 2.13 (0.88)
C2 (mean (SD)) 0.47 (0.50)
Stratified by
Overall
n 450.01
E (mean (SD)) 2.00 (0.82)
C (mean (SD)) 2.13 (0.88)
C2 (mean (SD)) 0.47 (0.50)
Stratified by E:C1
1:0 2:0 3:0 1:1 2:1
n 100.01 100.00 100.00 50.00 50.00
E (mean (SD)) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00) 1.00 (0.00) 2.00 (0.00)
C (mean (SD)) 1.60 (0.49) 1.60 (0.49) 1.60 (0.49) 3.20 (0.40) 3.20 (0.40)
C2 (mean (SD)) 0.60 (0.49) 0.60 (0.49) 0.60 (0.49) 0.20 (0.40) 0.20 (0.40)
Stratified by E:C1
3:1 p test
n 50.00
E (mean (SD)) 3.00 (0.00) <0.001
C (mean (SD)) 3.20 (0.40) <0.001
C2 (mean (SD)) 0.20 (0.40) <0.001
Stratified by E:C1
1:0 2:0 3:0 1:1 2:1
n 100.01 100.00 100.00 50.00 50.00
E (mean (SD)) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00) 1.00 (0.00) 2.00 (0.00)
C (mean (SD)) 1.60 (0.49) 1.60 (0.49) 1.60 (0.49) 3.20 (0.40) 3.20 (0.40)
C2 (mean (SD)) 0.60 (0.49) 0.60 (0.49) 0.60 (0.49) 0.20 (0.40) 0.20 (0.40)
Stratified by E:C1
3:1 p test
n 50.00
E (mean (SD)) 3.00 (0.00) <0.001
C (mean (SD)) 3.20 (0.40) <0.001
C2 (mean (SD)) 0.20 (0.40) <0.001
Stratified by E
1 2 3 p test
n 150.012 150.003 150.000
E (mean (SD)) 1.000 (0.000) 2.000 (0.000) 3.000 (0.000) <0.00001
C (mean (SD)) 2.133 (0.885) 2.133 (0.886) 2.133 (0.886) 1.00000
C2 (mean (SD)) 0.467 (0.499) 0.467 (0.500) 0.467 (0.500) 1.00000
Stratified by E
1 2 3 p test
n 150.012 150.003 150.000
E (mean (SD)) 1.000 (0.000) 2.000 (0.000) 3.000 (0.000) <0.00001
C (mean (SD)) 2.133 (0.885) 2.133 (0.886) 2.133 (0.886) 1.00000
C2 (mean (SD)) 0.467 (0.499) 0.467 (0.500) 0.467 (0.500) 1.00000
Stratified by E
1 2 3
n 150.01 150.00 150.00
E (mean (SD)) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00)
C (mean (SD)) 2.13 (0.89) 2.13 (0.89) 2.13 (0.89)
C2 (mean (SD)) 0.47 (0.50) 0.47 (0.50) 0.47 (0.50)
Stratified by E
1 2 3
n 150.01 150.00 150.00
E (mean (SD)) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00)
C (mean (SD)) 2.13 (0.89) 2.13 (0.89) 2.13 (0.89)
C2 (mean (SD)) 0.47 (0.50) 0.47 (0.50) 0.47 (0.50)
Stratified by E
1 2 3 p
n 150.01 150.00 150.00
E (mean (SD)) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00) <0.001
C (median [IQR]) 2.00 [1.00, 3.00] 2.00 [1.00, 3.00] 2.00 [1.00, 3.00] 1.000
C2 (mean (SD)) 0.47 (0.50) 0.47 (0.50) 0.47 (0.50) 1.000
Stratified by E
test
n
E (mean (SD))
C (median [IQR]) nonnorm
C2 (mean (SD))
Stratified by E
1 2 3 p
n 150.01 150.00 150.00
E (mean (SD)) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00) <0.001
C (median [IQR]) 2.00 [1.00, 3.00] 2.00 [1.00, 3.00] 2.00 [1.00, 3.00] 1.000
C2 (mean (SD)) 0.47 (0.50) 0.47 (0.50) 0.47 (0.50) 1.000
Stratified by E
test
n
E (mean (SD))
C (median [IQR]) nonnorm
C2 (mean (SD))
Stratified by E
1 2 3
n 150.01 150.00 150.00
E (mean (SD)) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00)
C (median [range]) 2.00 [1.00, 4.00] 2.00 [1.00, 4.00] 2.00 [1.00, 4.00]
C2 (mean (SD)) 0.47 (0.50) 0.47 (0.50) 0.47 (0.50)
Stratified by E
p test
n
E (mean (SD)) <0.001
C (median [range]) 1.000 nonnorm
C2 (mean (SD)) 1.000
Stratified by E
1 2 3
n 150.01 150.00 150.00
E (mean (SD)) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00)
C (median [range]) 2.00 [1.00, 4.00] 2.00 [1.00, 4.00] 2.00 [1.00, 4.00]
C2 (mean (SD)) 0.47 (0.50) 0.47 (0.50) 0.47 (0.50)
Stratified by E
p test
n
E (mean (SD)) <0.001
C (median [range]) 1.000 nonnorm
C2 (mean (SD)) 1.000
Stratified by E
1 2 3 p test
n 150.01 150.00 150.00
E (mean (SD)) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00) <0.001
C (mean (SD)) 2.13 (0.89) 2.13 (0.89) 2.13 (0.89) 1.000
C2 (mean (SD)) 0.47 (0.50) 0.47 (0.50) 0.47 (0.50) 1.000
Stratified by E
1 2 3 p test
n 150.01 150.00 150.00
E (mean (SD)) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00) <0.001
C (mean (SD)) 2.13 (0.89) 2.13 (0.89) 2.13 (0.89) 1.000
C2 (mean (SD)) 0.47 (0.50) 0.47 (0.50) 0.47 (0.50) 1.000
Stratified by E
1 2 3 p test
n 150.01 150.00 150.00
E 1.00 (0.00) 2.00 (0.00) 3.00 (0.00) <0.001
C 2.13 (0.89) 2.13 (0.89) 2.13 (0.89) 1.000
C2 0.47 (0.50) 0.47 (0.50) 0.47 (0.50) 1.000
Stratified by E
1 2 3 p test
n 150.01 150.00 150.00
E 1.00 (0.00) 2.00 (0.00) 3.00 (0.00) <0.001
C 2.13 (0.89) 2.13 (0.89) 2.13 (0.89) 1.000
C2 0.47 (0.50) 0.47 (0.50) 0.47 (0.50) 1.000
"Stratified by E"
"" "1" "2" "3" "p" "test"
"n" "150.01" "150.00" "150.00" "" ""
"E (mean (SD))" "1.00 (0.00)" "2.00 (0.00)" "3.00 (0.00)" "<0.001" ""
"C (mean (SD))" "2.13 (0.89)" "2.13 (0.89)" "2.13 (0.89)" "1.000" ""
"C2 (mean (SD))" "0.47 (0.50)" "0.47 (0.50)" "0.47 (0.50)" "1.000" ""
"Stratified by E"
"" "1" "2" "3" "p" "test"
"n" "150.01" "150.00" "150.00" "" ""
"E (mean (SD))" "1.00 (0.00)" "2.00 (0.00)" "3.00 (0.00)" "<0.001" ""
"C (mean (SD))" "2.13 (0.89)" "2.13 (0.89)" "2.13 (0.89)" "1.000" ""
"C2 (mean (SD))" "0.47 (0.50)" "0.47 (0.50)" "0.47 (0.50)" "1.000" ""
Stratified by E
Overall 1 2 3 p test
n 450.01 150.01 150.00 150.00
E (mean (SD)) 2.00 (0.82) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00) <0.001
C (mean (SD)) 2.13 (0.88) 2.13 (0.89) 2.13 (0.89) 2.13 (0.89) 1.000
C2 (mean (SD)) 0.47 (0.50) 0.47 (0.50) 0.47 (0.50) 0.47 (0.50) 1.000
Stratified by E
SMD
n
E (mean (SD)) Inf
C (mean (SD)) <0.001
C2 (mean (SD)) <0.001
Stratified by E
Overall 1 2 3 p test
n 450.01 150.01 150.00 150.00
E (mean (SD)) 2.00 (0.82) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00) <0.001
C (mean (SD)) 2.13 (0.88) 2.13 (0.89) 2.13 (0.89) 2.13 (0.89) 1.000
C2 (mean (SD)) 0.47 (0.50) 0.47 (0.50) 0.47 (0.50) 0.47 (0.50) 1.000
Stratified by E
SMD
n
E (mean (SD)) Inf
C (mean (SD)) <0.001
C2 (mean (SD)) <0.001
Stratified by E:C1
Overall 1:0 2:0 3:0 1:1
n 450.01 100.01 100.00 100.00 50.00
E (mean (SD)) 2.00 (0.82) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00) 1.00 (0.00)
C (mean (SD)) 2.13 (0.88) 1.60 (0.49) 1.60 (0.49) 1.60 (0.49) 3.20 (0.40)
C2 (mean (SD)) 0.47 (0.50) 0.60 (0.49) 0.60 (0.49) 0.60 (0.49) 0.20 (0.40)
Stratified by E:C1
2:1 3:1 p test SMD
n 50.00 50.00
E (mean (SD)) 2.00 (0.00) 3.00 (0.00) <0.001 Inf
C (mean (SD)) 3.20 (0.40) 3.20 (0.40) <0.001 2.137
C2 (mean (SD)) 0.20 (0.40) 0.20 (0.40) <0.001 0.534
Stratified by E:C1
Overall 1:0 2:0 3:0 1:1
n 450.01 100.01 100.00 100.00 50.00
E (mean (SD)) 2.00 (0.82) 1.00 (0.00) 2.00 (0.00) 3.00 (0.00) 1.00 (0.00)
C (mean (SD)) 2.13 (0.88) 1.60 (0.49) 1.60 (0.49) 1.60 (0.49) 3.20 (0.40)
C2 (mean (SD)) 0.47 (0.50) 0.60 (0.49) 0.60 (0.49) 0.60 (0.49) 0.20 (0.40)
Stratified by E:C1
2:1 3:1 p test SMD
n 50.00 50.00
E (mean (SD)) 2.00 (0.00) 3.00 (0.00) <0.001 Inf
C (mean (SD)) 3.20 (0.40) 3.20 (0.40) <0.001 2.137
C2 (mean (SD)) 0.20 (0.40) 0.20 (0.40) <0.001 0.534
Stratified by RIAGENDR
1 2 p test
n 134944553.92 141591892.00
HI_CHOL (mean (SD)) 0.10 (0.30) 0.12 (0.33) 0.009
Stratified by RIAGENDR
1 2 p test
n 134944553.92 141591892.00
HI_CHOL (mean (SD)) 0.10 (0.30) 0.12 (0.33) 0.009
Stratified by RIAGENDR
1 2 p test
n 134944553.92 141591892.00
HI_CHOL (median [IQR]) 0.00 [0.00, 0.00] 0.00 [0.00, 0.00] 0.009 nonnorm
Stratified by RIAGENDR
1 2 p test
n 134944553.92 141591892.00
HI_CHOL (median [range]) 0.00 [0.00, 1.00] 0.00 [0.00, 1.00] 0.009 nonnorm
Stratified by RIAGENDR
1 2 p test
n 134944553.92 141591892.00
HI_CHOL (mean (SD)) 0.10 (0.30) 0.12 (0.33) 0.0092211
Stratified by RIAGENDR
1 2 p test
n 134944553.92 141591892.00
HI_CHOL (median [IQR]) 0.00 [0.00, 0.00] 0.00 [0.00, 0.00] 0.0092211 nonnorm
Stratified by RIAGENDR
1 2 p test
n 134944553.923 141591891.998
race (%) 0.042
1 21381884.189 (15.845) 20251367.389 ( 14.303)
2 89315751.415 (66.187) 92486945.142 ( 65.319)
3 15045455.461 (11.149) 17967228.319 ( 12.689)
4 9201462.858 ( 6.819) 10886351.148 ( 7.689)
agecat (%) 0.001
(0,19] 29299546.109 (21.712) 28150760.544 ( 19.882)
(19,39] 40497613.070 (30.011) 40640361.534 ( 28.702)
(39,59] 41053579.409 (30.423) 42817044.014 ( 30.240)
(59,Inf] 24093815.335 (17.855) 29983725.904 ( 21.176)
RIAGENDR = 2 (%) 0.000 ( 0.000) 141591891.998 (100.000) <0.001
Stratified by RIAGENDR
1 2 p test
n 134944553.923 141591891.998
race (%) 0.042
1 21381884.189 (15.845) 20251367.389 ( 14.303)
2 89315751.415 (66.187) 92486945.142 ( 65.319)
3 15045455.461 (11.149) 17967228.319 ( 12.689)
4 9201462.858 ( 6.819) 10886351.148 ( 7.689)
agecat (%) 0.001
(0,19] 29299546.109 (21.712) 28150760.544 ( 19.882)
(19,39] 40497613.070 (30.011) 40640361.534 ( 28.702)
(39,59] 41053579.409 (30.423) 42817044.014 ( 30.240)
(59,Inf] 24093815.335 (17.855) 29983725.904 ( 21.176)
RIAGENDR = 2 (%) 0.000 ( 0.000) 141591891.998 (100.000) <0.001
Stratified by RIAGENDR
1 2 p test
n 134944553.9 141591892.0
race (%) 0.0416288
1 21381884.2 (15.8) 20251367.4 ( 14.3)
2 89315751.4 (66.2) 92486945.1 ( 65.3)
3 15045455.5 (11.1) 17967228.3 ( 12.7)
4 9201462.9 ( 6.8) 10886351.1 ( 7.7)
agecat (%) 0.0011757
(0,19] 29299546.1 (21.7) 28150760.5 ( 19.9)
(19,39] 40497613.1 (30.0) 40640361.5 ( 28.7)
(39,59] 41053579.4 (30.4) 42817044.0 ( 30.2)
(59,Inf] 24093815.3 (17.9) 29983725.9 ( 21.2)
RIAGENDR = 2 (%) 0.0 ( 0.0) 141591892.0 (100.0) <0.0000001
Stratified by RIAGENDR
1 2 p
n 134944553.92 141591892.00
HI_CHOL (mean (SD)) 0.10 (0.30) 0.12 (0.33) 0.0092211
race (%) 0.0416288
1 21381884.2 (15.8) 20251367.4 ( 14.3)
2 89315751.4 (66.2) 92486945.1 ( 65.3)
3 15045455.5 (11.1) 17967228.3 ( 12.7)
4 9201462.9 ( 6.8) 10886351.1 ( 7.7)
agecat (%) 0.0011757
(0,19] 29299546.1 (21.7) 28150760.5 ( 19.9)
(19,39] 40497613.1 (30.0) 40640361.5 ( 28.7)
(39,59] 41053579.4 (30.4) 42817044.0 ( 30.2)
(59,Inf] 24093815.3 (17.9) 29983725.9 ( 21.2)
RIAGENDR = 2 (%) 0.0 ( 0.0) 141591892.0 (100.0) <0.0000001
Stratified by RIAGENDR
test
n
HI_CHOL (mean (SD))
race (%)
1
2
3
4
agecat (%)
(0,19]
(19,39]
(39,59]
(59,Inf]
RIAGENDR = 2 (%)
Stratified by RIAGENDR
1 2 p
n 134944553.92 141591892.00
HI_CHOL (mean (SD)) 0.10 (0.30) 0.12 (0.33) 0.0092211
race (%) 0.0416288
1 21381884.2 (15.8) 20251367.4 ( 14.3)
2 89315751.4 (66.2) 92486945.1 ( 65.3)
3 15045455.5 (11.1) 17967228.3 ( 12.7)
4 9201462.9 ( 6.8) 10886351.1 ( 7.7)
agecat (%) 0.0011757
(0,19] 29299546.1 (21.7) 28150760.5 ( 19.9)
(19,39] 40497613.1 (30.0) 40640361.5 ( 28.7)
(39,59] 41053579.4 (30.4) 42817044.0 ( 30.2)
(59,Inf] 24093815.3 (17.9) 29983725.9 ( 21.2)
RIAGENDR = 2 (%) 0.0 ( 0.0) 141591892.0 (100.0) <0.0000001
Stratified by RIAGENDR
test
n
HI_CHOL (mean (SD))
race (%)
1
2
3
4
agecat (%)
(0,19]
(19,39]
(39,59]
(59,Inf]
RIAGENDR = 2 (%)
Stratified by RIAGENDR
1 2
n 134944553.92 141591892.00
HI_CHOL (median [IQR]) 0.00 [0.00, 0.00] 0.00 [0.00, 0.00]
race (%)
1 21381884.2 (15.8) 20251367.4 ( 14.3)
2 89315751.4 (66.2) 92486945.1 ( 65.3)
3 15045455.5 (11.1) 17967228.3 ( 12.7)
4 9201462.9 ( 6.8) 10886351.1 ( 7.7)
agecat (%)
(0,19] 29299546.1 (21.7) 28150760.5 ( 19.9)
(19,39] 40497613.1 (30.0) 40640361.5 ( 28.7)
(39,59] 41053579.4 (30.4) 42817044.0 ( 30.2)
(59,Inf] 24093815.3 (17.9) 29983725.9 ( 21.2)
RIAGENDR = 2 (%) 0.0 ( 0.0) 141591892.0 (100.0)
Stratified by RIAGENDR
p test
n
HI_CHOL (median [IQR]) 0.0092211 nonnorm
race (%) 0.0416288
1
2
3
4
agecat (%) 0.0011757
(0,19]
(19,39]
(39,59]
(59,Inf]
RIAGENDR = 2 (%) <0.0000001
Stratified by RIAGENDR
1 2 p
n 134944553.92 141591892.00
HI_CHOL (mean (SD)) 0.10 (0.30) 0.12 (0.33) 0.009
race (%) 0.042
1 21381884.189 (15.845) 20251367.389 ( 14.303)
2 89315751.415 (66.187) 92486945.142 ( 65.319)
3 15045455.461 (11.149) 17967228.319 ( 12.689)
4 9201462.858 ( 6.819) 10886351.148 ( 7.689)
agecat (%) 0.001
(0,19] 29299546.109 (21.712) 28150760.544 ( 19.882)
(19,39] 40497613.070 (30.011) 40640361.534 ( 28.702)
(39,59] 41053579.409 (30.423) 42817044.014 ( 30.240)
(59,Inf] 24093815.335 (17.855) 29983725.904 ( 21.176)
RIAGENDR = 2 (%) 0.000 ( 0.000) 141591891.998 (100.000) <0.001
Stratified by RIAGENDR
test
n
HI_CHOL (mean (SD))
race (%)
1
2
3
4
agecat (%)
(0,19]
(19,39]
(39,59]
(59,Inf]
RIAGENDR = 2 (%)
Stratified by RIAGENDR
1 2
n 134944553.92 141591892.00
HI_CHOL (median [IQR]) 0.00 [0.00, 0.00] 0.00 [0.00, 0.00]
race (%)
1 21381884.2 (15.8) 20251367.4 ( 14.3)
2 89315751.4 (66.2) 92486945.1 ( 65.3)
3 15045455.5 (11.1) 17967228.3 ( 12.7)
4 9201462.9 ( 6.8) 10886351.1 ( 7.7)
agecat (%)
(0,19] 29299546.1 (21.7) 28150760.5 ( 19.9)
(19,39] 40497613.1 (30.0) 40640361.5 ( 28.7)
(39,59] 41053579.4 (30.4) 42817044.0 ( 30.2)
(59,Inf] 24093815.3 (17.9) 29983725.9 ( 21.2)
RIAGENDR = 2 (%) 0.0 ( 0.0) 141591892.0 (100.0)
Stratified by RIAGENDR
p test
n
HI_CHOL (median [IQR]) 0.0092211 nonnorm
race (%) 0.0416288
1
2
3
4
agecat (%) 0.0011757
(0,19]
(19,39]
(39,59]
(59,Inf]
RIAGENDR = 2 (%) <0.0000001
### Summary of continuous variables ###
: Overall
n miss p.miss mean sd median p25 p75 min max
E 450 0 0 2.0 0.8 2 1 3 1 3
C 450 0 0 2.1 0.9 2 1 3 1 4
C2 450 0 0 0.5 0.5 0 0 1 0 1
=======================================================================================
### Summary of categorical variables ###
: Overall
var n miss p.miss level freq percent cum.percent
Y 450.0 0.3 0.1 0 272.7 60.6 60.6
1 177.0 39.4 100.0
C1 450.0 0.0 0.0 0 300.0 66.7 66.7
1 150.0 33.3 100.0
### Summary of continuous variables ###
: Overall
n miss p.miss mean sd median p25 p75 min max
E 450 0 0 2.0 0.8 2 1 3 1 3
C 450 0 0 2.1 0.9 2 1 3 1 4
C2 450 0 0 0.5 0.5 0 0 1 0 1
=======================================================================================
### Summary of categorical variables ###
: Overall
var n miss p.miss level freq percent cum.percent
Y 450.0 0.0 0.0 0 272.7 60.6 60.6
1 177.0 39.3 99.9
<NA> 0.3 0.1 100.0
C1 450.0 0.0 0.0 0 300.0 66.7 66.7
1 150.0 33.3 100.0
### Summary of continuous variables ###
E: 1
n miss p.miss mean sd median p25 p75 min max
E 150 0 0 1.0 0.0 1 1 1 1 1
C 150 0 0 2.1 0.9 2 1 3 1 4
C2 150 0 0 0.5 0.5 0 0 1 0 1
------------------------------------------------------------
E: 2
n miss p.miss mean sd median p25 p75 min max
E 150 0 0 2.0 0.0 2 2 2 2 2
C 150 0 0 2.1 0.9 2 1 3 1 4
C2 150 0 0 0.5 0.5 0 0 1 0 1
------------------------------------------------------------
E: 3
n miss p.miss mean sd median p25 p75 min max
E 150 0 0 3.0 0.0 3 3 3 3 3
C 150 0 0 2.1 0.9 2 1 3 1 4
C2 150 0 0 0.5 0.5 0 0 1 0 1
p-values
pNormal pNonNormal
E 0.0000000 0.0000000
C 0.9999992 0.9999991
C2 0.9999993 0.9999993
Standardize mean differences
average 1 vs 2 1 vs 3 2 vs 3
E Inf Inf Inf Inf
C 6.823456e-05 9.934218e-05 1.023522e-04 3.009264e-06
C2 6.404022e-05 9.606505e-05 7.471632e-05 2.133930e-05
=======================================================================================
### Summary of categorical variables ###
E: 1
var n miss p.miss level freq percent cum.percent
Y 150.0 0.3 0.2 0 90.7 60.6 60.6
1 59.0 39.4 100.0
C1 150.0 0.0 0.0 0 100.0 66.7 66.7
1 50.0 33.3 100.0
------------------------------------------------------------
E: 2
var n miss p.miss level freq percent cum.percent
Y 150.0 0.0 0.0 0 91.0 60.7 60.7
1 59.0 39.3 100.0
C1 150.0 0.0 0.0 0 100.0 66.7 66.7
1 50.0 33.3 100.0
------------------------------------------------------------
E: 3
var n miss p.miss level freq percent cum.percent
Y 150.0 0.0 0.0 0 91.0 60.7 60.7
1 59.0 39.3 100.0
C1 150.0 0.0 0.0 0 100.0 66.7 66.7
1 50.0 33.3 100.0
p-values
pApprox pExact
Y 0.9998243 NA
C1 0.9999998 NA
Standardize mean differences
average 1 vs 2 1 vs 3 2 vs 3
Y 9.949589e-04 1.492438e-03 1.488617e-03 3.821227e-06
C1 3.770972e-05 4.242269e-05 5.656458e-05 1.414189e-05
### Summary of continuous variables ###
E:C1: 1:0
n miss p.miss mean sd median p25 p75 min max
E 100 0 0 1.0 0.0 1 1 1 1 1
C 100 0 0 1.6 0.5 2 1 2 1 2
C2 100 0 0 0.6 0.5 1 0 1 0 1
------------------------------------------------------------
E:C1: 2:0
n miss p.miss mean sd median p25 p75 min max
E 100 0 0 2.0 2e-16 2 2 2 2 2
C 100 0 0 1.6 5e-01 2 1 2 1 2
C2 100 0 0 0.6 5e-01 1 0 1 0 1
------------------------------------------------------------
E:C1: 3:0
n miss p.miss mean sd median p25 p75 min max
E 100 0 0 3.0 0.0 3 3 3 3 3
C 100 0 0 1.6 0.5 2 1 2 1 2
C2 100 0 0 0.6 0.5 1 0 1 0 1
------------------------------------------------------------
E:C1: 1:1
n miss p.miss mean sd median p25 p75 min max
E 50 0 0 1.0 0.0 1 1 1 1 1
C 50 0 0 3.2 0.4 3 3 3 3 4
C2 50 0 0 0.2 0.4 0 0 0 0 1
------------------------------------------------------------
E:C1: 2:1
n miss p.miss mean sd median p25 p75 min max
E 50 0 0 2.0 0.0 2 2 2 2 2
C 50 0 0 3.2 0.4 3 3 3 3 4
C2 50 0 0 0.2 0.4 0 0 0 0 1
------------------------------------------------------------
E:C1: 3:1
n miss p.miss mean sd median p25 p75 min max
E 50 0 0 3.0 0.0 3 3 3 3 3
C 50 0 0 3.2 0.4 3 3 3 3 4
C2 50 0 0 0.2 0.4 0 0 0 0 1
p-values
pNormal pNonNormal
E 0.000000e+00 0.00000e+00
C 2.518377e-307 0.00000e+00
C2 1.950910e-37 1.95091e-37
Standardize mean differences
average 1 vs 2 1 vs 3 1 vs 4 1 vs 5 1 vs 6
E Inf 6.350292e+15 Inf 0.0000000 Inf Inf
C 2.1373647 1.710913e-04 0.000146495 3.5608223 3.5673100 3.5708236
C2 0.5343248 1.710913e-04 0.000146495 0.8900053 0.8916269 0.8925051
2 vs 3 2 vs 4 2 vs 5 2 vs 6 3 vs 4 3 vs 5
E 6.350292e+15 6.350292e+15 1.4100480 6.350292e+15 Inf Inf
C 2.439672e-05 3.556921e+00 3.5633882 3.566891e+00 3.5525326 3.5589756
C2 2.439672e-05 8.892636e-01 0.8908805 8.917561e-01 0.8881331 0.8897439
3 vs 6 4 vs 5 4 vs 6 5 vs 6
E 0.0000000 Inf Inf Inf
C 3.5624649 0 0 0
C2 0.8906162 0 0 0
=======================================================================================
### Summary of categorical variables ###
E:C1: 1:0
var n miss p.miss level freq percent cum.percent
Y 100.0 0.3 0.3 0 77.7 77.9 77.9
1 22.0 22.1 100.0
C1 100.0 0.0 0.0 0 100.0 100.0 100.0
1 0.0 0.0 100.0
------------------------------------------------------------
E:C1: 2:0
var n miss p.miss level freq percent cum.percent
Y 100.0 0.0 0.0 0 78.0 78.0 78.0
1 22.0 22.0 100.0
C1 100.0 0.0 0.0 0 100.0 100.0 100.0
1 0.0 0.0 100.0
------------------------------------------------------------
E:C1: 3:0
var n miss p.miss level freq percent cum.percent
Y 100.0 0.0 0.0 0 78.0 78.0 78.0
1 22.0 22.0 100.0
C1 100.0 0.0 0.0 0 100.0 100.0 100.0
1 0.0 0.0 100.0
------------------------------------------------------------
E:C1: 1:1
var n miss p.miss level freq percent cum.percent
Y 50.0 0.0 0.0 0 13.0 26.0 26.0
1 37.0 74.0 100.0
C1 50.0 0.0 0.0 0 0.0 0.0 0.0
1 50.0 100.0 100.0
------------------------------------------------------------
E:C1: 2:1
var n miss p.miss level freq percent cum.percent
Y 50.0 0.0 0.0 0 13.0 26.0 26.0
1 37.0 74.0 100.0
C1 50.0 0.0 0.0 0 0.0 0.0 0.0
1 50.0 100.0 100.0
------------------------------------------------------------
E:C1: 3:1
var n miss p.miss level freq percent cum.percent
Y 50.0 0.0 0.0 0 13.0 26.0 26.0
1 37.0 74.0 100.0
C1 50.0 0.0 0.0 0 0.0 0.0 0.0
1 50.0 100.0 100.0
p-values
pApprox pExact
Y 4.540885e-31 NA
C1 4.640660e-128 NA
Standardize mean differences
average 1 vs 2 1 vs 3 1 vs 4 1 vs 5 1 vs 6 2 vs 3
Y 0.7311319 0.001480611 0.001486405 1.216879 1.216879 1.216879 5.793469e-06
C1 NaN 0.000000000 0.000000000 NaN NaN NaN 0.000000e+00
2 vs 4 2 vs 5 2 vs 6 3 vs 4 3 vs 5 3 vs 6 4 vs 5 4 vs 6 5 vs 6
Y 1.218891 1.218891 1.218891 1.218899 1.218899 1.218899 0 0 0
C1 NaN NaN NaN NaN NaN NaN 0 0 0
### Summary of continuous variables ###
E:C1: 1:0
n miss p.miss mean sd median p25 p75 min max
E 100 0 0 1 0.0 1 1 1 1 1
C 100 0 0 2 0.5 2 1 2 1 2
------------------------------------------------------------
E:C1: 2:0
n miss p.miss mean sd median p25 p75 min max
E 100 0 0 2 2e-16 2 2 2 2 2
C 100 0 0 2 5e-01 2 1 2 1 2
------------------------------------------------------------
E:C1: 3:0
n miss p.miss mean sd median p25 p75 min max
E 100 0 0 3 0.0 3 3 3 3 3
C 100 0 0 2 0.5 2 1 2 1 2
------------------------------------------------------------
E:C1: 1:1
n miss p.miss mean sd median p25 p75 min max
E 50 0 0 1 0.0 1 1 1 1 1
C 50 0 0 3 0.4 3 3 3 3 4
------------------------------------------------------------
E:C1: 2:1
n miss p.miss mean sd median p25 p75 min max
E 50 0 0 2 0.0 2 2 2 2 2
C 50 0 0 3 0.4 3 3 3 3 4
------------------------------------------------------------
E:C1: 3:1
n miss p.miss mean sd median p25 p75 min max
E 50 0 0 3 0.0 3 3 3 3 3
C 50 0 0 3 0.4 3 3 3 3 4
p-values
pNormal pNonNormal
E 0.000000e+00 0
C 2.518377e-307 0
Standardize mean differences
average 1 vs 2 1 vs 3 1 vs 4 1 vs 5 1 vs 6 2 vs 3
E Inf 6.350292e+15 Inf 0.000000 Inf Inf 6.350292e+15
C 2.137365 1.710913e-04 0.000146495 3.560822 3.56731 3.570824 2.439672e-05
2 vs 4 2 vs 5 2 vs 6 3 vs 4 3 vs 5 3 vs 6 4 vs 5 4 vs 6
E 6.350292e+15 1.410048 6.350292e+15 Inf Inf 0.000000 Inf Inf
C 3.556921e+00 3.563388 3.566891e+00 3.552533 3.558976 3.562465 0 0
5 vs 6
E Inf
C 0
### Summary of categorical variables ###
E:C1: 1:0
var n miss p.miss level freq percent cum.percent
Y 100.0 0.3 0.3 0 77.7 77.9 77.9
1 22.0 22.1 100.0
C1 100.0 0.0 0.0 0 100.0 100.0 100.0
1 0.0 0.0 100.0
------------------------------------------------------------
E:C1: 2:0
var n miss p.miss level freq percent cum.percent
Y 100.0 0.0 0.0 0 78.0 78.0 78.0
1 22.0 22.0 100.0
C1 100.0 0.0 0.0 0 100.0 100.0 100.0
1 0.0 0.0 100.0
------------------------------------------------------------
E:C1: 3:0
var n miss p.miss level freq percent cum.percent
Y 100.0 0.0 0.0 0 78.0 78.0 78.0
1 22.0 22.0 100.0
C1 100.0 0.0 0.0 0 100.0 100.0 100.0
1 0.0 0.0 100.0
------------------------------------------------------------
E:C1: 1:1
var n miss p.miss level freq percent cum.percent
Y 50.0 0.0 0.0 0 13.0 26.0 26.0
1 37.0 74.0 100.0
C1 50.0 0.0 0.0 0 0.0 0.0 0.0
1 50.0 100.0 100.0
------------------------------------------------------------
E:C1: 2:1
var n miss p.miss level freq percent cum.percent
Y 50.0 0.0 0.0 0 13.0 26.0 26.0
1 37.0 74.0 100.0
C1 50.0 0.0 0.0 0 0.0 0.0 0.0
1 50.0 100.0 100.0
------------------------------------------------------------
E:C1: 3:1
var n miss p.miss level freq percent cum.percent
Y 50.0 0.0 0.0 0 13.0 26.0 26.0
1 37.0 74.0 100.0
C1 50.0 0.0 0.0 0 0.0 0.0 0.0
1 50.0 100.0 100.0
p-values
pApprox pExact
Y 4.540885e-31 NA
C1 4.640660e-128 NA
Standardize mean differences
average 1 vs 2 1 vs 3 1 vs 4 1 vs 5 1 vs 6 2 vs 3
Y 0.7311319 0.001480611 0.001486405 1.216879 1.216879 1.216879 5.793469e-06
C1 NaN 0.000000000 0.000000000 NaN NaN NaN 0.000000e+00
2 vs 4 2 vs 5 2 vs 6 3 vs 4 3 vs 5 3 vs 6 4 vs 5 4 vs 6 5 vs 6
Y 1.218891 1.218891 1.218891 1.218899 1.218899 1.218899 0 0 0
C1 NaN NaN NaN NaN NaN NaN 0 0 0
Stratified by ESA
1 2 3 p test
n 2.00 2.00 2.00
alive (mean (SD)) 24.50 (0.71) 39.50 (13.44) 75.00 (7.07) 0.098
ambulance = 2 (%) 50.0 50.0 50.0 1.000
== testthat results ===========================================================
[ OK: 542 | SKIPPED: 0 | WARNINGS: 135 | FAILED: 17 ]
1. Failure: ModuleFormatPValues: alignes output vertically (@test-modules-print.R#343)
2. Failure: ModuleConvertNormal: returns a column of numeric mean and a formatted column of character (SD) (@test-modules-print.R#447)
3. Failure: ModuleConvertNormal: returns a column of numeric mean and a formatted column of character (SD) (@test-modules-print.R#451)
4. Failure: ModuleConvertNormal: returns a column of numeric mean and a formatted column of character (SD) (@test-modules-print.R#455)
5. Failure: ModuleConvertNormal: returns a column of numeric mean and a formatted column of character (SD) (@test-modules-print.R#459)
6. Failure: ModuleConvertNormal: respects formatOptions (@test-modules-print.R#466)
7. Failure: ModuleConvertNormal: respects formatOptions (@test-modules-print.R#471)
8. Failure: ModuleConvertNormal: respects formatOptions (@test-modules-print.R#476)
9. Failure: ModuleConvertNormal: respects formatOptions (@test-modules-print.R#481)
1. ...
Error: testthat unit tests failed
Execution halted
Flavor: r-oldrel-windows-ix86+x86_64