Package: RefFreeEWAS
Version: 2.2
Date: 2018-12-14
Title: EWAS using Reference-Free DNA Methylation Mixture Deconvolution
Author: E. Andres Houseman, Sc.D.
Maintainer: E. Andres Houseman <eahouseman@gmail.com>
Depends: R (>= 3.2.2), quadprog
Description: 
    Reference-free method for conducting EWAS while deconvoluting DNA methylation 
    arising as mixtures of cell types.  The older method 
    (Houseman et al., 2014,<doi:10.1093/bioinformatics/btu029>) is similar to 
    surrogate variable analysis (SVA and ISVA), except that it makes additional use 
    of a biological mixture assumption.
    The newer method (Houseman et al., 2016, <doi:10.1186/s12859-016-1140-4>) is similar 
    to non-negative matrix factorization, with additional constraints 
    and additional utilities.
License: GPL (>= 2)
NeedsCompilation: no
Packaged: 2018-12-14 05:31:13 UTC; EHouseman
Repository: CRAN
Date/Publication: 2018-12-14 06:00:03 UTC
Built: R 4.0.0; ; 2020-04-26 14:25:28 UTC; windows
