Package: Keyboard
Type: Package
Title: Bayesian Designs for Early Phase Clinical Trials
Version: 0.1.0
Author: Hongying Sun, Li Tang, and Haitao Pan
Maintainer: Hongying Sun <hongyingsun1101@gmail.com>
Imports: Iso
Suggests: epade
Description: We developed a package 'Keyboard' for designing single-agent, drug-combination, or phase I/II dose-finding clinical trials. The 'Keyboard' designs are novel early phase trial designs that can be implemented simply and transparently, similar to the 3+3 design, but yield excellent performance, comparable to those of more-complicated, model-based designs (Yan F, Mandrekar SJ, Yuan Y (2017) <doi:10.1158/1078-0432.CCR-17-0220>, Li DH, Whitmore JB, Guo W, Ji Y. (2017) <doi:10.1158/1078-0432.CCR-16-1125>,  Liu S, Johnson VE (2016) <doi:10.1093/biostatistics/kxv040>, Zhou Y, Lee JJ, Yuan Y (2019) <doi:10.1002/sim.8475>, Pan H, Lin R, Yuan Y (2020) <doi:10.1016/j.cct.2020.105972). The 'Keyboard' package provides tools for designing, conducting, and analyzing single-agent, drug-combination, and phase I/II dose-finding clinical trials.  
Depends: R (>= 3.4.0), Rcpp (>= 0.12.0), methods
License: GPL-2
Encoding: UTF-8
LazyData: true
RoxygenNote: 7.1.0
Repository: CRAN
NeedsCompilation: no
Packaged: 2020-07-06 19:18:34 UTC; hongyingsun
Date/Publication: 2020-07-07 09:00:13 UTC
Built: R 3.6.3; ; 2020-08-05 01:32:42 UTC; windows
