Package: LEANR
Type: Package
Title: Finds "Local Subnetworks" Within an Interaction Network which
        Show Enrichment for Differentially Expressed Genes
Version: 1.4.9
Date: 2016-11-11
Author: Frederik Gwinner
Maintainer: Frederik Gwinner <frederik.gwinner@gmail.com>
Description: Implements the method described in "Network-based analysis of omics data: The LEAN method" [Gwinner Boulday (2016) <DOI:10.1093/bioinformatics/btw676>]
 Given a protein interaction network and a list of p-values describing a measure of interest (as e.g. differential gene expression) this method
 computes an enrichment p-value for the protein neighborhood of each gene and compares it to a background distribution of randomly drawn p-values.
 The resulting scores are corrected for multiple testing and significant hits are returned in tabular format.
License: GPL-3
Packaged: 2016-11-11 23:37:29 UTC; fgwinner
Depends: R (>= 2.14), igraph(>= 0.7.1), foreach(>= 1.4.2)
Suggests: knitr, doMC, rmarkdown, ROCR, testthat
VignetteBuilder: knitr
NeedsCompilation: no
Repository: CRAN
Date/Publication: 2016-11-12 15:47:01
Built: R 4.1.0; ; 2020-08-03 08:26:59 UTC; windows
