Blissindependence       Bliss Independence Model
CPBootstrap             Estimate CP matrix with bootstrap
GetStartGuess           Estimate initial values for dose-response curve
                        fit
L4                      4-parameter logistic dose-response function
bootstrapData           Data generating function used for constructing
                        null distribution of meanR and maxR statistics
boxcox.transformation   Apply two-parameter Box-Cox transformation
coef.MarginalFit        Coefficients from marginal model estimation
constructFormula        Construct a model formula from parameter
                        constraint matrix
contour.ResponseSurface
                        Method for plotting of contours based on maxR
                        statistics
df.residual.MarginalFit
                        Residual degrees of freedom in marginal model
                        estimation
directAntivirals        Partial data with combination experiments of
                        direct-acting antivirals
directAntivirals_ALL    Full data with combination experiments of
                        direct-acting antivirals
fitMarginals            Fit two 4-parameter log-logistic functions for
                        a synergy experiment
fitSurface              Fit response surface model and compute meanR
                        and maxR statistics
fitted.MarginalFit      Compute fitted values from monotherapy
                        estimation
fitted.ResponseSurface
                        Predicted values of the response surface
                        according to the given null model
generalizedLoewe        Compute combined predicted response from drug
                        doses according to standard or generalized
                        Loewe model.
generateData            Generate data from parameters of marginal
                        monotherapy model
get.abs_tval            Return absolute t-value, used in optimization
                        call in 'optim.boxcox'
get.summ.data           Summarize data by factor
getTransformations      Return a list with transformation functions
harbronLoewe            Alternative Loewe generalization
hsa                     Highest Single Agent model
initialMarginal         Estimate initial values for fitting marginal
                        dose-response curves
isobologram             Isobologram of the response surface predicted
                        by the null model
marginalNLS             Fit two 4-parameter log-logistic functions with
                        non-linear least squares
marginalOptim           Fit two 4-parameter log-logistic functions with
                        common baseline
maxR                    Compute maxR statistic for each off-axis dose
                        combination
meanR                   Compute meanR statistic for the estimated model
optim.boxcox            Find optimal Box-Cox transformation parameters
outsidePoints           List non-additive points
plot.MarginalFit        Plot monotherapy curve estimates
plot.ResponseSurface    Method for plotting response surface objects
plot.maxR               Plot of maxR object
plot.meanR              Plot bootstrapped cumulative distribution
                        function of meanR null distribution
plotResponseSurface     Plot response surface
predict.MarginalFit     Predict values on the dose-response curve
predictOffAxis          Compute off-axis predictions
print.summary.MarginalFit
                        Print method for summary of 'MarginalFit'
                        object
print.summary.ResponseSurface
                        Print method for the summary function of
                        'ResponseSurface' object
print.summary.maxR      Print summary of maxR object
print.summary.meanR     Print summary of meanR object
residuals.MarginalFit   Residuals from marginal model estimation
runBIGL                 Run the BIGL application for demonstrating
                        response surfaces
simulateNull            Simulate data from a given null model and
                        monotherapy coefficients
summary.MarginalFit     Summary of 'MarginalFit' object
summary.ResponseSurface
                        Summary of 'ResponseSurface' object
summary.maxR            Summary of maxR object
summary.meanR           Summary of meanR object
vcov.MarginalFit        Estimate of coefficient variance-covariance
                        matrix
