# In-depth Characterization and Analysis of Mutational Signatures ('ICAMS')

## Documentation for package ‘ICAMS’ version 2.1.2

- DESCRIPTION file.

## Help Pages

all.abundance | K-mer abundances.
AnnotateDBSVCF | Add sequence context and transcript information to an in-memory DBS VCF.
AnnotateIDVCF | Add sequence context to an in-memory ID (insertion/deletion) VCF, and confirm that they match the given reference genome.
AnnotateSBSVCF | Add sequence context and transcript information to an in-memory SBS VCF.
as.catalog | Create a catalog from a 'matrix', 'data.frame', or 'vector'.
Canonicalize1Del | Given a deletion and its sequence context, categorize it.
catalog.row.order | Standard order of row names in a catalog.
catalog.row.order.sp | Standard order of row names in a catalog.
CatalogRowOrder | Standard order of row names in a catalog.
Collapse144CatalogTo78 | "Collapse" a catalog.
Collapse1536CatalogTo96 | "Collapse" a catalog.
Collapse192CatalogTo96 | "Collapse" a catalog.
CollapseCatalog | "Collapse" a catalog.
FindDelMH | Return the length of microhomology at a deletion.
FindMaxRepeatDel | Return the number of repeat units in which a deletion is embedded.
gene.expression.data.HepG2 | Example gene expression data from two cell lines.
gene.expression.data.MCF10A | Example gene expression data from two cell lines.
GeneExpressionData | Example gene expression data from two cell lines.
GetMutectVAF | Extract the VAFs (variant allele frequencies) and read depth information from a VCF file.
GetStrelkaVAF | Extract the VAFs (variant allele frequencies) and read depth information from a VCF file.
GetVAF | Extract the VAFs (variant allele frequencies) and read depth information from a VCF file.
ICAMS | ICAMS: In-depth Characterization and Analysis of Mutational Signatures
MutectVCFFilesToCatalog | Create SBS, DBS and Indel catalogs from Mutect VCF files
MutectVCFFilesToCatalogAndPlotToPdf | Create SBS, DBS and Indel catalogs from Mutect VCF files and plot them to PDF
MutectVCFFilesToZipFile | Create a zip file which contains catalogs and plot PDFs from Mutect VCF files
PlotCatalog | Plot *one* spectrum or signature.
PlotCatalogToPdf | Plot catalog to a PDF file.
PlotTransBiasGeneExp | Plot transcription strand bias with respect to gene expression values.
PlotTransBiasGeneExpToPdf | Plot transcription strand bias with respect to gene expression values to a PDF file.
ReadAndSplitMutectVCFs | Read and split Mutect VCF files.
ReadAndSplitStrelkaSBSVCFs | Read and split Strelka SBS VCF files.
ReadCatalog | Read catalog.
ReadStrelkaIDVCFs | Read Strelka ID (small insertion and deletion) VCF files.
revc | Reverse complement every string in 'string.vec'.
StrelkaIDVCFFilesToCatalog | Create ID (small insertion and deletion) catalog from Strelka ID VCF files
StrelkaIDVCFFilesToCatalogAndPlotToPdf | Create ID (small insertion and deletion) catalog from Strelka ID VCF files and plot them to PDF
StrelkaIDVCFFilesToZipFile | Create a zip file which contains ID (small insertion and deletion) catalog and plot PDF from Strelka ID VCF files
StrelkaSBSVCFFilesToCatalog | Create SBS and DBS catalogs from Strelka SBS VCF files.
StrelkaSBSVCFFilesToCatalogAndPlotToPdf | Create SBS and DBS catalogs from Strelka SBS VCF files and plot them to PDF
StrelkaSBSVCFFilesToZipFile | Create a zip file which contains catalogs and plot PDFs from Strelka SBS VCF files
trans.ranges.GRCh37 | Transcript ranges data
trans.ranges.GRCh38 | Transcript ranges data
trans.ranges.GRCm38 | Transcript ranges data
TranscriptRanges | Transcript ranges data
TransformCatalog | Transform between counts and density spectrum catalogs and counts and density signature catalogs.
VCFsToDBSCatalogs | Create DBS catalogs from VCFs
VCFsToIDCatalogs | Create ID (small insertion and deletion) catalog from ID VCFs
VCFsToSBSCatalogs | Create SBS catalogs from SBS VCFs
WriteCatalog | Write a catalog