Package: nlmixr
Type: Package
Title: Nonlinear Mixed Effects Models in Population Pharmacokinetics
        and Pharmacodynamics
Depends: R (>= 3.2)
Imports: Rcpp (>= 0.12.3), brew, lattice, parallel, lbfgs, dparser,
        methods, ggplot2, memoise, rex, minqa, Matrix, numDeriv,
        R.utils, n1qn1, PreciseSums, fastGHQuad, crayon, cli,
        RcppArmadillo (>= 0.5.600.2.0), vpc (>= 1.0.0), RxODE(>=
        0.8.0-4), nlme, magrittr, tidyr
Suggests: knitr, rmarkdown, dplyr, data.table, lbfgsb3, testthat,
        madness, devtools, expm, matrixcalc, reshape2, nloptr, ucminf
Version: 1.0.0-7
Authors@R: c(person("Matthew","Fidler",
      role = "aut", email = "matthew.fidler@gmail.com"),      
   person("Yuan", "Xiong", 
      role = "aut", email = "yuan.xiong@gmail.com"),
   person("Rik", "Schoemaker", 
      role = "aut", email = "rik.schoemaker@occams.com"),
   person("Justin", "Wilkins", 
      role = "aut", email = "justin.wilkins@occams.com"),
   person("Mirjam","Trame",
      role = "aut", email = "mirjam.trame@gmail.com"),   
   person("Teun","Post",
      role = "aut", email = "t.post@lapp.nl"),   
   person("Robert","Leary", role = "ctb"),
   person("Wenping", "Wang", 
      role = c("aut", "cre"), email = "wwang8198@gmail.com"),
   person("Hadley","Wickham", role = "ctb"),
   person("Dirk","Eddelbuettel",
      role = "cph", email = "edd@debian.org"),   
   person("David","Ardia",role = "cph"),
   person("Katharine","Mullen",role = "cph")
   )
Description: Fit and compare nonlinear mixed-effects models in differential
    equations with flexible dosing information commonly seen in pharmacokinetics
    and pharmacodynamics (Almquist, Leander, and Jirstrand 2015 
    <doi:10.1007/s10928-015-9409-1>). Differential equation solving is 
    by compiled C code provided in the 'RxODE' package
    (Wang, Hallow, and James 2015 <doi:10.1002/psp4.12052>).
License: GPL (>= 2)
NeedsCompilation: yes
LinkingTo: dparser(>= 0.1.8), Rcpp (>= 0.12.3), RcppEigen (>=
        0.3.3.3.0), StanHeaders, BH
URL: https://github.com/nlmixrdevelopment/nlmixr
LazyData: true
VignetteBuilder: knitr
RoxygenNote: 6.1.0
Packaged: 2018-09-22 12:09:18 UTC; annie
Maintainer: Wenping Wang <wwang8198@gmail.com>
Author: Matthew Fidler [aut],
  Yuan Xiong [aut],
  Rik Schoemaker [aut],
  Justin Wilkins [aut],
  Mirjam Trame [aut],
  Teun Post [aut],
  Robert Leary [ctb],
  Wenping Wang [aut, cre],
  Hadley Wickham [ctb],
  Dirk Eddelbuettel [cph],
  David Ardia [cph],
  Katharine Mullen [cph]
Repository: CRAN
Date/Publication: 2018-09-23 14:00:03 UTC
Built: R 3.4.4; x86_64-w64-mingw32; 2019-04-25 22:21:11 UTC; windows
Archs: i386, x64
