Package: HiCblock
Type: Package
Title: Systematic Analysis of Architectural Proteins and Functional
        Elements in Blocking Long-Range Contacts Between Loci
Version: 1.4
Depends: R (>= 3.4.0)
Imports: IRanges, GenomeInfoDb, methods, GenomicRanges, Matrix, glmnet,
        rtracklayer, HiTC, MASS, S4Vectors
Date: 2018-04-18
Author: Raphael Mourad
Maintainer: Raphael Mourad <raphael.mourad@ibcg.biotoul.fr>
Description: Here we propose a model to systematically analyze the roles of architectural proteins and functional elements in blocking long-range contacts between loci. The proposed model does not rely on topologically associating domain (TAD) mapping from Hi-C data. Instead of testing the enrichment or influence of protein binding at TAD borders, the model directly estimates the blocking effect of proteins on long-range contacts between flanking loci, making the model intuitive and biologically meaningful.
License: GPL-2
NeedsCompilation: no
Packaged: 2018-04-18 18:29:41 UTC; mourad
Repository: CRAN
Date/Publication: 2018-04-18 22:46:01 UTC
Built: R 3.4.4; ; 2019-04-25 20:57:51 UTC; windows
