Penalized Likelihood Estimation and Dynamic Prediction under the Joint Frailty-Copula Models Between Tumour Progression and Death for Meta-Analysis

Documentation for package ‘joint.Cox’ version 2.14

joint.Cox-package	Penalized Likelihood Estimation and Dynamic Prediction under the Joint Frailty-Copula Models Between Tumour Progression and Death for Meta-Analysis
dataOvarian	Meta-analytic data of ovarian cancer patients combining 4 independent studies.
dataOvarian1	Data on time-to-recurrence and 158 gene expressions for 912 ovarian cancer patients from 4 independent studies.
dataOvarian2	Data on time-to-death and 128 gene expressions for 912 ovarian cancer patients from 4 independent studies.
F.KM	Prediction of death using the Kaplan-Meier estimator
F.prediction	Dynamic prediction of death
F.window	Prediction of death
F.windows	Prediction of death
I.spline	I-Spline function
joint.Cox	Penalized Likelihood Estimation and Dynamic Prediction under the Joint Frailty-Copula Models Between Tumour Progression and Death for Meta-Analysis
jointCox.indep.reg	Penalized Likelihood Estimation under the Joint Cox Models Between Tumour Progression and Death for Meta-Analysis
jointCox.reg	Penalized Likelihood Estimation under the Joint Cox Models Between Tumour Progression and Death for Meta-Analysis
M.spline	M-Spline function
splineCox.reg	Likelihood cross-validation (LCV) for the Cox model with penalized splines