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|                                                 |                  Cox                  |                 Shared                |                 Nested                |                Additive               |Joint standard *(Bivariate: 1 RE + 1 TE)*| Joint cluster *(Bivariate: 1 RE + 1 TE)*|Joint general *(Bivariate: 1 RE + 1 TE)*|Joint nested *(Bivariate: 1 RE + 1 TE)*|Joint longitudinal *(Bivariate:  1 LO + 1 TE)*|Joint trivariate *(Trivariate: 1 LO + 1 RE + 1 TE)*|Joint Multivariate *(Trivariate: 2 RE + 1 TE)*| 
|:------------------------------------------------|:-------------------------------------:|:-------------------------------------:|:-------------------------------------:|:-------------------------------------:|:--------------------------------------:|:--------------------------------------:|:-------------------------------------:|:------------------------------------:|:------------------------------------------:|:-------------------------------------:|:-------------------------------------:|
|  `Available  options `                          |                                       |                                       |                                       |                                       |                                        |                                        |                                       |                                      |                                            |                                       |                                       |                                  
| Gamma distribution                              |                                       | ![](blue_x.png)                       | ![](blue_x.png)                       |                                       |  ![](blue_x.png)                       |  ![](blue_x.png)                       | ![](blue_x.png)                       | ![](blue_x.png)                      |                                            |                                       |                                       |                       
| Log-Normal distribution                         |                                       | ![](blue_x.png)                       |                                       | ![](blue_x.png)                       |  ![](blue_x.png)                       |                                        |                                       |                                      | ![](blue_x.png)                            | ![](blue_x.png)                       | ![](blue_x.png)                       |
| Left-truncation                                 | ![](blue_x.png)                       | ![](blue_x.png)                       | ![](blue_x.png)                       |                                       |                                        |                                        |                                       |                                      |                                            |                                       |                                       |
| Interval Censoring                              | ![](blue_x.png)                       | ![](blue_x.png)                       |                                       |                                       |  ![](orange_x.png)                     |  ![](orange_x.png)                     |                                       |                                      |                                            |                                       |                                       |
| Two strata                                      | ![](blue_x.png)                       | ![](blue_x.png)                       | ![](blue_x.png)                       | ![](blue_x.png)                       |                                        |                                        |                                       |                                      |                                            |                                       |                                       |
| More strata (max=6)                             | ![](blue_x.png)                       | ![](blue_x.png)                       |                                       |                                       |  ![](blue_x.png)                       |                                        |                                       |                                      |                                            |                                       |                                       |
| Time-dependant covariates                       | ![](blue_x.png)                       | ![](blue_x.png)                       |                                       |                                       |  ![](blue_x.png)                       |  ![](blue_x.png)                       |                                       |                                      |                                            |                                       |                                       |
| Calendar timescale                              | ![](blue_x.png)                       | ![](blue_x.png)                       | ![](blue_x.png)                       |                                       |  ![](blue_x.png)                       |                                        |                                       | ![](blue_x.png)                      |                                            | ![](blue_x.png)                       | ![](blue_x.png)                       |    
| Weibull                                         | ![](blue_x.png)                       | ![](blue_x.png)                       | ![](blue_x.png)                       | ![](blue_x.png)                       |  ![](blue_x.png)                       |  ![](blue_x.png)                       |                                       | ![](blue_x.png)                      | ![](blue_x.png)                            | ![](blue_x.png)                       | ![](blue_x.png)                       |
| Piecewise                                       | ![](blue_x.png)                       | ![](blue_x.png)                       | ![](blue_x.png)                       | ![](blue_x.png)                       |  ![](blue_x.png)                       |  ![](blue_x.png)                       |                                       |                                      |                                            |                                       | ![](blue_x.png)                       |
|     `Available output`                          |                                       |                                       |                                       |                                       |                                        |                                        |                                       |                                      |                                            |                                       |                                       |
| Predicted frailties                             |                                       | ![](blue_x.png)                       | ![](blue_x.png)                       | ![](blue_x.png)                       |  ![](blue_x.png)                       |                                        |                                       | ![](blue_x.png)                      | ![](blue_x.png)                            | ![](blue_x.png)                       |                                       |        
| Variances of the frailties                      |                                       | ![](blue_x.png)                       |                                       |                                       |                                        |                                        |                                       |                                      |                                            |                                       |                                       |
| Martingale residuals                            | ![](blue_x.png)                       | ![](blue_x.png)                       | ![](blue_x.png)                       | ![](blue_x.png)                       |  ![](blue_x.png)                       |                                        |                                       | ![](blue_x.png)                      | ![](blue_x.png)                            | ![](blue_x.png)                       |                                       |
|     `Prediction methods `                       |                                       |                                       |                                       |                                       |                                        |                                        |                                       |                                      |                                            |                                       |                                       |                                  
| Marginal prediction of a terminal event         | ![](blue_x.png)                       | ![](blue_x.png)                       |                                       |                                       |  ![](blue_x.png)                       |                                        |                                       | ![](blue_x.png)                      | ![](blue_x.png)                            | ![](blue_x.png)                       |                                       |                                       
| Conditional prediction of a terminal event      | ![](blue_x.png)                       | ![](blue_x.png)                       |                                       |                                       |                                        |                                        |                                       |                                      |                                            |                                       |                                       |                                       
| Marginal prediction of a new recurrent event    | 			                          | ![](blue_x.png)                       |                                       |                                       |  ![](blue_x.png)                       |                                        |                                       |                                      | 			                                | 		                                |                                       |                                       
| Conditional prediction of a new recurrent event | 			                          | ![](blue_x.png)                       |                                       |                                       |                                        |                                        |                                       |                                      | 			                                | 		                                |                                       |                                       
|     `Model evaluation `                         |                                       |                                       |                                       |                                       |                                        |                                        |                                       |                                      |                                            |                                       |                                       |                                  
| Cmeasures                                       | ![](blue_x.png)                       |                                       |                                       |                                       |                                        |                                        |                                       |                                      |                                            |                                       |                                       |
| Epoce                                           |                                       |                                       |                                       |                                       |  ![](blue_x.png)                       |                                        |                                       |                                      | ![](blue_x.png)                            | ![](blue_x.png)                       |                                       |

Table 1: Package characteristics. Blue cross is for option available for a given type of model in the package on CRAN, orange cross is for option included in the package but not on CRAN yet. Empty cells mean that an option is not available for a given type of model (either not coded yet or simply not applicable). RE = Recurrent Event ; TE = Terminal Event ; LO = Longitudinal Outcome







