Adverse Outcome Pathway Analysis

Documentation for package ‘aop’ version 1.0.0

aop_backdoor	Backdoor Causal Network Analysis for AOPs
aop_cytoscape	aop_cytoscape class
aop_cytoscape-class	aop_cytoscape class
bmr	bmr class
bmr-class	bmr class
bootstrap_metaregression	Perform Bootstrap Metaregression
calculate_confidence_and_median	Calculate the confidence envelope and the median for the bootstrap metaregression concentration response models.
convert_aop_to_graph	Convert AOP to Graph
convert_cytoscape_to_aop	Convert Cytoscape Graph to an AOP
getAOPNodeName	Get Node Name from ID
getAOPNodeName-method	Get Node Name from ID
internal_model_fits	An internal function for calculating interpolation values.
oxybenzone	High Throughput Screening Data (Tox21) for Assessing the Estrogenicity of Oxybenzone
plot_metaregression_confidence_envelope	Plot the metaregression confidence envelope and median results from the bootstrap metaregression models.
plot_metaregression_spaghetti_plot	Make a spaghetti plot for the metaregression results
plot_slope_analysis	Plot the median slope
pod_envelope_analysis	This function calculates the chemical's point of departure.
pod_slope_analysis	This is intended as an internal function to facilitate the identification of the concentration where the asymptote is likely to end based on a slope threshold, so that the mean of the upper confidence limit for the asymptote can be calculated.
slope_pod_analysis	Slope-based POD analysis