Methods for Family-Based Rare-Variant Genetic Association Tests

Documentation for package ‘RVPedigree’ version 0.0.3

RVPedigree-package	RVPedigree: A package for region-based genetic association tests.
ASKAT.region	Run the ASKAT method on a genomic region defined by a start and a stop base pair coordinate
Estim.H0.ASKAT	Estimation of the variance components under the null model using the ASKAT method
Estim.H0.NormalizedASKAT	Estimation of the variance components under the null model using the normalized ASKAT method
Estim.H0.VCC	Estimate the model parameters under the null model
GetRelMatrix	Estimate relationship matrix based on pedigree or genomic data
Normality.test	Test for normality of the trait/phenotype
NormalizedASKAT.region	Run the normalized ASKAT method on a genomic region defined by a start and a stop base pair coordinate
readMapFile	Read file with information about SNPs chromosome and position, for example from regular PLINK .map OR .bim file
RVPedigree	RVPedigree main function
VCC1.region	Run the VC-C1 method on a genomic region defined by a start and a stop base pair coordinate
VCC2.region	Run the VC-C2 method on a genomic region defined by a start and a stop base pair coordinate
VCC3.region	Run the VC-C3 method on a genomic region defined by a start and a stop base pair coordinate