# Methods for Family-Based Rare-Variant Genetic Association Tests

## Documentation for package ‘RVPedigree’ version 0.0.3

- DESCRIPTION file.
- User guides, package vignettes and other documentation.

## Help Pages

RVPedigree-package | RVPedigree: A package for region-based genetic association tests.
ASKAT.region | Run the ASKAT method on a genomic region defined by a start and a stop base pair coordinate
Estim.H0.ASKAT | Estimation of the variance components under the null model using the ASKAT method
Estim.H0.NormalizedASKAT | Estimation of the variance components under the null model using the normalized ASKAT method
Estim.H0.VCC | Estimate the model parameters under the null model
GetRelMatrix | Estimate relationship matrix based on pedigree or genomic data
Normality.test | Test for normality of the trait/phenotype
NormalizedASKAT.region | Run the normalized ASKAT method on a genomic region defined by a start and a stop base pair coordinate
readMapFile | Read file with information about SNPs chromosome and position, for example from regular PLINK .map OR .bim file
RVPedigree | RVPedigree main function
VCC1.region | Run the VC-C1 method on a genomic region defined by a start and a stop base pair coordinate
VCC2.region | Run the VC-C2 method on a genomic region defined by a start and a stop base pair coordinate
VCC3.region | Run the VC-C3 method on a genomic region defined by a start and a stop base pair coordinate