Study Planning and Adaptation of Sample Size

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Documentation for package ‘spass’ version 1.0

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bssr.1subgroup Blinded Sample Size Recalculation for a One Subgroup Design
bssr.gee.1subgroup Blinded Sample Size Recalculation for longitudinal data in a One Subgroup Design
bssr.nb.inar1 Blinded Sample Size Reestimation for Longitudinal Count Data using the NB-INAR(1) Model
estimcov Estimation of variance, intra-subject-correlation and dropout
fit.nb.inar1 Fitting Longitudinal Data with Negative Binomial Marginal Distribution and Autoregressive Correlation Structure of Order One: NB-INAR(1)
gen_cov_cor Generation of covariance- or correlation-matrices
n.1subgroup Sample Size Calculation for a One Subgroup Design
n.gee.1subgroup Sample Size estimation for longitudinal GEE Models when testing 1 coefficient
n.nb.inar1 Sample Size Calculation for Comparing Two Groups when observing Longitudinal Count Data with marginal Negative Binomial Distribution and Autoregressive Correlation Structure of Order One: NB-INAR(1)
r.1subgroup Generate dataset of normal distributed observations in a one subgroup design
r.gee.1subgroup Generate a dataset of normally distributed repeated measures in a one subgroup setting
rnbinom.inar1 Generate Time Series with Negative Binomial Distribution and Autoregressive Correlation Structure of Order One: NB-INAR(1)
sandwich Estimate the Robust covariance estimator for GEE (weigthed GEE if missing occures) of Regressor parameters
sandwich2 Generate Time Series with Negative Binomial Distribution and Autoregressive Correlation Structure of Order One: NB-INAR(1)
sim.bssr.1subgroup Simulation of a One Subgroup Design with Internal Pilot Study
sim.bssr.gee.1subgroup Simulation of a longitudinal One Subgroup Design with Internal Pilot Study
summary.bssrest Summarizing Blinded Sample Size Reestimation
summary.ssest Summarizing Initial Sample Size Estimates