# Smoothing-splines Mixed-effects Models

## Documentation for package ‘sme’ version 0.8

- DESCRIPTION file.
- User guides, package vignettes and other documentation.

## Help Pages

AICc | The corrected AIC
BICn | An alternative BIC for longitudinal models
getRoughnessMatrix | Extract the roughness matrix used in an SME model fit
inflammatory | Example gene transcript from an experiment on children suffering from an inflammatory condition
MTB | Ten example gene transcripts from an experiment investigating the _in vitro_ transcriptional response to _M.Tuberculosis_
plot.sme | Visualisation of smoothing-splines mixed-effects models
plotSmeDiagnostic | Diagnostic plot of the residuals for a fitted smoothing-splines mixed-effects model
plotSmeModel | Visualisation of a fitted smoothing-splines mixed-effects model
plotSmeRaw | Visualisation of raw data for a smoothing-splines mixed-effects model
sme | Smoothing-splines mixed-effects models
sme.data.frame | Smoothing-splines mixed-effects model fit(s) from a data.frame object
sme.default | Smoothing-splines mixed-effects models
sme.list | Carry out mulitple independent smoothing-splines mixed-effects model fits simultaneously
smeObject | Fitted sme Object