Package: joineRML
Type: Package
Title: Joint Modelling of Multivariate Longitudinal Data and
        Time-to-Event Outcomes
Version: 0.2.0
Authors@R: c(
    person("Graeme L.", "Hickey", email = "graeme.hickey@liverpool.ac.uk", 
        role = c("cre", "aut")),
    person("Pete", "Philipson", email = "pete.philipson@northumbria.ac.uk", 
        role = "aut"),
    person("Andrea", "Jorgensen", email = "aljorgen@liverpool.ac.uk", 
        role = "aut"),
    person("Ruwanthi", "Kolamunnage-Dona", email = "kdrr@liverpool.ac.uk", 
        role = "aut"),
    person("Paula", "Williamson", email = "p.r.williamson@liverpool.ac.uk",
        role = "ctb"),
    person("Dimitris", "Rizopoulos", email = "d.rizopoulos@erasmusmc.nl",
        role = c("ctb", "dtc"),
        comment = "data/renal.rda, R/hessian.R, R/vcov.R")
    )
Maintainer: Graeme L. Hickey <graeme.hickey@liverpool.ac.uk>
Date: 2017-03-25
Description: Fits the joint model proposed by Henderson and colleagues (2000) 
    <doi:10.1093/biostatistics/1.4.465>, but extended to the case of multiple 
    continuous longitudinal measures. The time-to-event data is modelled using a 
    Cox proportional hazards regression model with time-varying covariates. The 
    multiple longitudinal outcomes are modelled using a multivariate version of the 
    Laird and Ware linear mixed model. The association is captured by a multivariate
    latent Gaussian process. The model is estimated using a Monte Carlo Expectation 
    Maximization algorithm. This project is funded by the Medical Research Council 
    (Grant number MR/M013227/1).
License: GPL-3 | file LICENSE
URL: https://github.com/graemeleehickey/joineRML/
BugReports: https://github.com/graemeleehickey/joineRML/issues
LazyData: true
Depends: R (>= 3.1.1), nlme, survival
Imports: ggplot2, graphics, lme4 (>= 1.1-8), MASS, Matrix, Rcpp (>=
        0.12.7), stats, utils
LinkingTo: Rcpp, RcppArmadillo
RoxygenNote: 6.0.1
Suggests: JM, joineR, knitr, rmarkdown, R.rsp, testthat
VignetteBuilder: knitr, R.rsp
NeedsCompilation: yes
Packaged: 2017-03-27 08:51:59 UTC; graemeleehickey
Author: Graeme L. Hickey [cre, aut],
  Pete Philipson [aut],
  Andrea Jorgensen [aut],
  Ruwanthi Kolamunnage-Dona [aut],
  Paula Williamson [ctb],
  Dimitris Rizopoulos [ctb, dtc] (data/renal.rda, R/hessian.R, R/vcov.R)
Repository: CRAN
Date/Publication: 2017-03-27 14:04:09 UTC
Built: R 3.2.5; x86_64-w64-mingw32; 2017-04-20 08:25:04 UTC; windows
Archs: i386, x64
