Calculating Likelihoods by Pedigree Paring


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Documentation for package ‘clipp’ version 0.1.0

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dat_large Simulated data on one family with approximately 10,000 members.
dat_small Simulated data on 10 families with approximately 100 members each.
genotype_probabilities Calculate the genotype probabilities of a target person
geno_freq_HWE Calculate genotype frequencies from allele frequencies, assuming Hardy-Weinberg equilibrium
pedigree_loglikelihood Calculate the log-likelihoods of pedigrees
penet_large A penetrance matrix relating the phenotypes in 'dat_large' to three genotypes
penet_small A penetrance matrix relating the phenotypes of 'dat_small' to three genotypes
trans_monogenic The transmission matrix for a common genetic model